UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR424W

Length:

708

Number of sequences:

5887

Description:

YLR424W SPP382 SGDID:S000004416, Chr XII from 973395-975521, Genome Release 64-1-1, Verified ORF, "Essential protein that forms a dimer with Ntr2p; also forms a trimer, with Ntr2p and Prp43p, that is involved in spliceosome disassembly; found also in a multisubunit complex with the splicing factor Clf1p; suppressor of prp38-1 mutation"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q9UTK6	797	YKR3_SCHPO G-patch domain-containing protein ...	56	0.00004	50.8	43	57	GO:0005816; C:spindle pole body; IDA:PomBase.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:PomBase.
									GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0000390; P:spliceosomal complex disassembly; ISS:PomBase.
32	Q7PYU6	543	ZGPAT_ANOGA Zinc finger CCCH-type with G patc...	38	0.00007	49.7	47	66	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33	Q17CQ8	512	ZGPAT_AEDAE Zinc finger CCCH-type with G patc...	37	0.0003	47.8	51	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34	A4IGK4	838	RBM5_XENTR RNA-binding protein 5 OS=Xenopus t...	50	0.0003	47.8	46	60	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
35	A0JMV4	833	RBM5A_XENLA RNA-binding protein 5-A OS=Xenopu...	42	0.0004	47.4	52	64	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
36	Q6DDU9	749	RBM5B_XENLA RNA-binding protein 5-B OS=Xenopu...	41	0.0005	47.4	54	66	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
37	Q9NAA5	927	MTR1_CAEEL Cap-specific mRNA (nucleoside-2'-O...	74	0.0006	47	34	57
									GO:0004483; F:mRNA (nucleoside-2'-O-)-methyltransferase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006370; P:mRNA capping; ISS:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.
38	Q9NW75	528	GPTC2_HUMAN G patch domain-containing protein...	42	0.0007	46.2	48	67
									GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
39	B2GV05	815	RBM5_RAT RNA-binding protein 5 OS=Rattus norv...	42	0.001	46.2	52	64	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
40	Q91YE7	815	RBM5_MOUSE RNA-binding protein 5 OS=Mus muscu...	42	0.001	46.2	52	64	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
41	Q1RMU5	815	RBM5_BOVIN RNA-binding protein 5 OS=Bos tauru...	42	0.001	46.2	52	64	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
42	P52756	815	RBM5_HUMAN RNA-binding protein 5 OS=Homo sapi...	42	0.001	46.2	52	64	GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005681; C:spliceosomal complex; TAS:UniProtKB.
									GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003729; F:mRNA binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
43	Q7TQC7	527	GPTC2_MOUSE G patch domain-containing protein...	42	0.002	45.4	48	64
									GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
44	Q99KG3	930	RBM10_MOUSE RNA-binding protein 10 OS=Mus mus...	46	0.002	45.4	43	67	GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
45	P98175	930	RBM10_HUMAN RNA-binding protein 10 OS=Homo sa...	46	0.002	45.1	43	67	GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
46	P70501	852	RBM10_RAT RNA-binding protein 10 OS=Rattus no...	46	0.002	45.1	43	67	GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
47	Q8N5A5	531	ZGPAT_HUMAN Zinc finger CCCH-type with G patc...	89	0.012	42.4	29	49	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48	Q28H71	514	ZGPAT_XENTR Zinc finger CCCH-type with G patc...	33	0.021	41.6	55	70	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49	Q9SK49	497	C3H22_ARATH Zinc finger CCCH domain-containin...	37	0.023	41.6	49	62
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
50	P63123	156	VPK7_HUMAN HERV-K_1q23.3 provirus ancestral P...	31	0.026	39.7	48	71
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
51	Q7SXW2	504	ZGPAT_DANRE Zinc finger CCCH-type with G patc...	37	0.033	41.2	54	62	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52	P63131	156	VPK12_HUMAN HERV-K_1q22 provirus ancestral Pr...	28	0.042	38.9	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
53	P10265	156	VPK10_HUMAN HERV-K_5q33.3 provirus ancestral ...	28	0.042	38.9	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54	P63119	156	VPK1_HUMAN HERV-K_12q14.1 provirus ancestral ...	28	0.043	38.9	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
55	Q5PPF5	507	ZGPAT_RAT Zinc finger CCCH-type with G patch ...	71	0.044	40.8	34	51	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56	P63121	156	VPK5_HUMAN HERV-K_19p13.11 provirus ancestral...	28	0.047	38.9	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
57	P63124	156	VPK9_HUMAN HERV-K_5q13.3 provirus ancestral P...	28	0.049	38.9	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
58	Q9Y6I0	156	VPK2_HUMAN HERV-K_7p22.1 provirus ancestral P...	43	0.051	38.9	40	63
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
59	P63125	156	VPK17_HUMAN HERV-K_11q22.1 provirus ancestral...	28	0.053	38.5	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
60	Q5U4Z3	524	ZGPAT_XENLA Zinc finger CCCH-type with G patc...	33	0.053	40.4	55	67	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61	P63120	156	VPK3_HUMAN HERV-K_19q12 provirus ancestral Pr...	28	0.067	38.5	50	75
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.

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