rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q06409 | 1932 | YL422_YEAST DOCK-like protein YLR422W OS=Sacc... | 1932 | 0 | 3995 | 100 | 100 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | | 2 | Q8CIQ7 | 2027 | DOCK3_MOUSE Dedicator of cytokinesis protein ... | 636 | 1e-34 | 149 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 3 | Q8IZD9 | 2030 | DOCK3_HUMAN Dedicator of cytokinesis protein ... | 636 | 1e-34 | 149 | 24 | 44 | GO:0005737; C:cytoplasm; IDA:HPA. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q8N1I0 | 1966 | DOCK4_HUMAN Dedicator of cytokinesis protein ... | 411 | 1e-30 | 136 | 27 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0032420; C:stereocilium; ISS:HGNC. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; IPI:HGNC.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0048365; F:Rac GTPase binding; IDA:HGNC.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060326; P:cell chemotaxis; IMP:UniProtKB. | 5 | P59764 | 1978 | DOCK4_MOUSE Dedicator of cytokinesis protein ... | 411 | 2e-30 | 135 | 26 | 47 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0032420; C:stereocilium; IDA:HGNC. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060326; P:cell chemotaxis; ISS:UniProtKB. | 6 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 470 | 9e-29 | 130 | 26 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 7 | B2RY04 | 1868 | DOCK5_MOUSE Dedicator of cytokinesis protein ... | 446 | 8e-27 | 124 | 26 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | | 8 | Q8C3J5 | 1828 | DOCK2_MOUSE Dedicator of cytokinesis protein ... | 437 | 5e-25 | 118 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IMP:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0042608; F:T cell receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0046633; P:alpha-beta T cell proliferation; IMP:MGI.::GO:0006935; P:chemotaxis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0001768; P:establishment of T cell polarity; IMP:MGI.::GO:0001771; P:immunological synapse formation; IMP:MGI.::GO:0001766; P:membrane raft polarization; IMP:MGI.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI. | 9 | Q92608 | 1830 | DOCK2_HUMAN Dedicator of cytokinesis protein ... | 438 | 2e-23 | 113 | 24 | 46 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 10 | Q14185 | 1865 | DOCK1_HUMAN Dedicator of cytokinesis protein ... | 449 | 2e-22 | 109 | 23 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.::GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 11 | Q8BUR4 | 1865 | DOCK1_MOUSE Dedicator of cytokinesis protein ... | 449 | 3e-22 | 109 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 12 | Q8BIK4 | 2055 | DOCK9_MOUSE Dedicator of cytokinesis protein ... | 348 | 0.000000004 | 65.9 | 22 | 41 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 13 | Q9BZ29 | 2069 | DOCK9_HUMAN Dedicator of cytokinesis protein ... | 348 | 0.00000001 | 63.9 | 22 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 14 | Q96BY6 | 2186 | DOC10_HUMAN Dedicator of cytokinesis protein ... | 332 | 0.00000008 | 61.6 | 23 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 15 | Q96N67 | 2140 | DOCK7_HUMAN Dedicator of cytokinesis protein ... | 367 | 0.0000003 | 60.1 | 25 | 41 | GO:0030424; C:axon; TAS:BHF-UCL.::GO:0045178; C:basal part of cell; TAS:BHF-UCL.::GO:0030426; C:growth cone; TAS:BHF-UCL. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IDA:BHF-UCL.::GO:0007409; P:axonogenesis; IMP:BHF-UCL.::GO:0045200; P:establishment of neuroblast polarity; IMP:BHF-UCL.::GO:0000226; P:microtubule cytoskeleton organization; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL. | 16 | Q8R1A4 | 2130 | DOCK7_MOUSE Dedicator of cytokinesis protein ... | 367 | 0.0000006 | 58.5 | 25 | 41 | GO:0030424; C:axon; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043473; P:pigmentation; IMP:MGI. | 17 | Q8VDR9 | 2080 | DOCK6_MOUSE Dedicator of cytokinesis protein ... | 245 | 0.0000009 | 58.2 | 27 | 44 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q96HP0 | 2047 | DOCK6_HUMAN Dedicator of cytokinesis protein ... | 284 | 0.000005 | 55.5 | 26 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 19 | Q8BZN6 | 2150 | DOC10_MOUSE Dedicator of cytokinesis protein ... | 299 | 0.000005 | 55.5 | 22 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 20 | Q8NF50 | 2099 | DOCK8_HUMAN Dedicator of cytokinesis protein ... | 366 | 0.00001 | 54.7 | 24 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 21 | Q5JSL3 | 2073 | DOC11_HUMAN Dedicator of cytokinesis protein ... | 296 | 0.00001 | 54.7 | 22 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 22 | A2AF47 | 2073 | DOC11_MOUSE Dedicator of cytokinesis protein ... | 337 | 0.00001 | 54.3 | 21 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | | 23 | Q8C147 | 2100 | DOCK8_MOUSE Dedicator of cytokinesis protein ... | 342 | 0.00002 | 53.5 | 24 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q63603 | 720 | DOCK9_RAT Dedicator of cytokinesis protein 9 ... | 288 | 0.0007 | 48.1 | 21 | 40 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | Q9LKX9 | 867 | RBR1_MAIZE Retinoblastoma-related protein 1 O... | 107 | 0.028 | 43.1 | 33 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q8H0J6 | 866 | RBR2_MAIZE Retinoblastoma-related protein 2 O... | 107 | 0.27 | 40 | 32 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q296J6 | 279 | RRP15_DROPS RRP15-like protein OS=Drosophila ... | 40 | 0.73 | 37.7 | 45 | 58 | | | | | | | | | | | | | | | | | | | | | | 28 | Q64EW6 | 222 | SPC25_DROMA Kinetochore protein Spc25 OS=Dros... | 115 | 2.3 | 35.8 | 27 | 45 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0031262; C:Ndc80 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051311; P:meiotic metaphase plate congression; ISS:UniProtKB.::GO:0000212; P:meiotic spindle organization; ISS:UniProtKB.::GO:0007080; P:mitotic metaphase plate congression; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB. | 29 | A5UNK6 | 655 | UVRB_METS3 UvrABC system protein B OS=Methano... | 88 | 2.6 | 36.6 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 30 | C0QUE7 | 238 | PUR7_PERMH Phosphoribosylaminoimidazole-succi... | 70 | 5.7 | 34.7 | 29 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004639; F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; IEA:EC. | | | | | | | | | | GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. |