Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR398C
Length:
1287
Number of sequences:
5887
Description:
YLR398C SKI2 SGDID:S000004390, Chr XII from 919019-915156, Genome Release 64-1-1, reverse complement, Verified ORF, "Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q8N3C0    2202   ASCC3_HUMAN Activating signal cointegrator 1 ...1900.00001     53.5     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62E9PZJ8    2198   ASCC3_MOUSE Activating signal cointegrator 1 ...1900.000004     55.5     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63F1NTD6    2211   ASCC3_CHICK Activating signal cointegrator 1 ...1900.000009     54.3     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64Q8TDG4    1101   HELQ_HUMAN Helicase POLQ-like OS=Homo sapiens...1630.000000004     65.1     32     50GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
65P30015    1538   LHR_ECOLI Probable ATP-dependent helicase lhr...2560.0000007     57.8     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
66Q914M3    601   Y007_SIFVH Putative helicase 7 OS=(SIFV). GN=...930.0006     47.8     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
67O74727    737   SUV3_SACDO ATP-dependent RNA helicase SUV3, m...1100.000002     56.2     28     49GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
68P32580    737   SUV3_YEAST ATP-dependent RNA helicase SUV3, m...750.000003     55.5     36     57GO:0045025; C:mitochondrial degradosome; IDA:SGD.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:SGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000372; P:Group I intron splicing; IGI:SGD.::GO:0006264; P:mitochondrial DNA replication; IMP:SGD.::GO:0000957; P:mitochondrial RNA catabolic process; IMP:SGD.
69Q0UMB6    878   DBP10_PHANO ATP-dependent RNA helicase DBP10 ...1740.0002     50.1     29     45GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
70Q9FT70    1150   RQL4B_ARATH ATP-dependent DNA helicase Q-like...2340.0005     48.1     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
71Q57742    841   HELX_METJA Uncharacterized ATP-dependent heli...2140.0005     48.1     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
72A4IG62    763   SUV3_DANRE ATP-dependent RNA helicase SUPV3L1...960.002     46.2     38     54GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
73P50830    749   YPRA_BACSU Uncharacterized ATP-dependent heli...2210.003     45.8     21     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
74Q295E6    762   SUV3_DROPS ATP-dependent RNA helicase SUV3 ho...920.003     45.8     39     52GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.
75Q9VN03    763   SUV3_DROME ATP-dependent RNA helicase SUV3 ho...920.003     45.4     39     52GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.
76O94445    647   SUV3_SCHPO ATP-dependent RNA helicase suv3, m...760.005     45.1     34     54GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:PomBase.
77Q8IYB8    786   SUV3_HUMAN ATP-dependent RNA helicase SUPV3L1...960.005     45.1     40     52GO:0045025; C:mitochondrial degradosome; IDA:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.::GO:0003677; F:DNA binding; IMP:UniProtKB.::GO:0003678; F:DNA helicase activity; IMP:UniProtKB.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0070827; P:chromatin maintenance; IMP:UniProtKB.::GO:0006310; P:DNA recombination; IMP:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; IMP:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; IMP:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; IMP:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; IDA:UniProtKB.
78Q9FT73    705   RQL2_ARATH ATP-dependent DNA helicase Q-like ...1000.006     44.7     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006310; P:DNA recombination; IC:TAIR.::GO:0006281; P:DNA repair; IC:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.
79Q8TDD1    881   DDX54_HUMAN ATP-dependent RNA helicase DDX54 ...1730.009     44.3     27     43GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0030520; P:intracellular estrogen receptor signaling pathway; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q6BQ61    477   RRP3_DEBHA ATP-dependent rRNA helicase RRP3 O...1650.011     43.5     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
81A1D405    472   RRP3_NEOFI ATP-dependent rRNA helicase rrp3 O...2960.012     43.5     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
82Q80YD1    779   SUV3_MOUSE ATP-dependent RNA helicase SUPV3L1...560.012     43.5     46     59GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
83O27830    862   HELX_METTH Uncharacterized ATP-dependent heli...1540.013     43.5     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
84Q5EBA1    776   SUV3_RAT ATP-dependent RNA helicase SUPV3L1, ...560.013     43.5     46     59GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
85Q8L840    1188   RQL4A_ARATH ATP-dependent DNA helicase Q-like...1800.014     43.5     28     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0071215; P:cellular response to abscisic acid stimulus; IEP:UniProtKB.::GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0051276; P:chromosome organization; IMP:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:TAIR.
86P95949    875   HELX_SULSO Uncharacterized ATP-dependent heli...2210.015     43.5     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
87Q5ACK7    613   DRS1_CANAL ATP-dependent RNA helicase DRS1 OS...1800.016     43.1     23     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
88Q5ZJT0    794   SUV3_CHICK ATP-dependent RNA helicase SUPV3L1...980.016     43.1     38     53GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
89O49289    845   RH29_ARATH Putative DEAD-box ATP-dependent RN...1720.018     43.1     26     45GO:0005634; C:nucleus; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
90A3LZT3    931   DBP10_PICST ATP-dependent RNA helicase DBP10 ...1450.024     42.7     24     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
91A7EML8    482   RRP3_SCLS1 ATP-dependent rRNA helicase rrp3 O...1660.028     42.4     23     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
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