Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR397C
Length:
780
Number of sequences:
5887
Description:
YLR397C AFG2 SGDID:S000004389, Chr XII from 914892-912550, Genome Release 64-1-1, reverse complement, Verified ORF, "ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; may be involved in degradation of aberrant mRNAs"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q505J9    361   ATAD1_RAT ATPase family AAA domain-containing...2431e-34     140     34     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007612; P:learning; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.
512A2ZVG7    784   FTSH9_ORYSJ ATP-dependent zinc metalloproteas...2309e-29     126     34     50GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
513Q7ZZ25    380   ATD1A_DANRE ATPase family AAA domain-containi...2325e-36     144     34     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.
514O88967    715   YMEL1_MOUSE ATP-dependent zinc metalloproteas...2261e-32     138     35     54GO:0016020; C:membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
515B3DV46    636   FTSH1_METI4 ATP-dependent zinc metalloproteas...2185e-32     135     36     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
516C5J6A7    754   FTSH_MYCCR ATP-dependent zinc metalloprotease...2081e-30     132     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
517B1W303    588   ARC_STRGG Proteasome-associated ATPase OS=Str...2047e-38     153     38     59GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
518Q05AS3    603   SPAST_XENTR Spastin OS=Xenopus tropicalis (We...2312e-34     142     36     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
519Q96TA2    773   YMEL1_HUMAN ATP-dependent zinc metalloproteas...2263e-32     138     35     54GO:0016020; C:membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
520Q9RJ58    588   ARC_STRCO Proteasome-associated ATPase OS=Str...2042e-37     152     38     59GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
521Q9SD67    802   FTSH7_ARATH ATP-dependent zinc metalloproteas...2683e-38     156     36     54GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
522Q3JEE4    639   FTSH_NITOC ATP-dependent zinc metalloprotease...2764e-36     148     36     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
523P54351    752   NSF2_DROME Vesicle-fusing ATPase 2 OS=Drosoph...2155e-34     143     41     58GO:0005737; C:cytoplasm; NAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.
524Q9FGM0    806   FTSHB_ARATH ATP-dependent zinc metalloproteas...2322e-29     129     36     50GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; ISS:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; TAS:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.
525Q6H6R9    822   FTSH7_ORYSJ ATP-dependent zinc metalloproteas...2362e-36     150     39     55GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
526A9BJK3    645   FTSH3_PETMO ATP-dependent zinc metalloproteas...2557e-38     154     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
527Q6NW58    570   SPAST_DANRE Spastin OS=Danio rerio (Zebrafish...2261e-32     137     37     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0048676; P:axon extension involved in development; IMP:ZFIN.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:ZFIN.::GO:0031122; P:cytoplasmic microtubule organization; IMP:ZFIN.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:ZFIN.::GO:0045773; P:positive regulation of axon extension; IMP:ZFIN.::GO:0031117; P:positive regulation of microtubule depolymerization; IMP:ZFIN.::GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
528Q9VQN8    523   FIGL1_DROME Fidgetin-like protein 1 OS=Drosop...2992e-37     151     32     54GO:0005813; C:centrosome; IDA:FlyBase.::GO:0005694; C:chromosome; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; IMP:FlyBase.
GO:0051013; P:microtubule severing; IMP:FlyBase.::GO:0036078; P:minus-end specific microtubule depolymerization; IMP:FlyBase.::GO:0000091; P:mitotic anaphase A; IMP:FlyBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:FlyBase.
529Q925S8    715   YMEL1_RAT ATP-dependent zinc metalloprotease ...2263e-32     137     35     54GO:0016020; C:membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
530D3FA80    691   FTSH2_CONWI ATP-dependent zinc metalloproteas...2572e-35     147     35     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
531D2NT89    608   ARC_ROTMD AAA ATPase forming ring-shaped comp...1992e-35     146     36     59GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
532A8QFF6    454   SPAST_BRUMA Probable spastin homolog Bm1_5336...2893e-38     152     34     55GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
533Q88Z31    745   FTSH_LACPL ATP-dependent zinc metalloprotease...1945e-35     146     42     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
534C6VKW6    745   FTSH_LACPJ ATP-dependent zinc metalloprotease...1945e-35     146     42     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
535O67077    634   FTSH_AQUAE ATP-dependent zinc metalloprotease...1955e-35     145     37     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
536A9GRC9    619   FTSH1_SORC5 ATP-dependent zinc metalloproteas...2301e-37     152     39     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
537D5D8E3    619   FTSH_SULMD ATP-dependent zinc metalloprotease...2346e-33     138     32     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
538P52917    437   VPS4_YEAST Vacuolar protein sorting-associate...2322e-36     147     36     59GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.
GO:0070676; P:intralumenal vesicle formation; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0051260; P:protein homooligomerization; IDA:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
539B3PNH3    744   FTSH_MYCA5 ATP-dependent zinc metalloprotease...2082e-33     141     36     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
540B0B970    913   FTSH_CHLT2 ATP-dependent zinc metalloprotease...2173e-35     147     38     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
541Q793F9    437   VPS4A_RAT Vacuolar protein sorting-associated...2329e-37     148     34     59GO:0005769; C:early endosome; IDA:RGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016197; P:endosome transport; IC:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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