Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR389C
Length:
1027
Number of sequences:
5887
Description:
YLR389C STE23 SGDID:S000004381, Chr XII from 902660-899577, Genome Release 64-1-1, reverse complement, Verified ORF, "Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; expressed in both haploids and diploids; member of the insulin-degrading enzyme family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06010    1027   STE23_YEAST A-factor-processing enzyme OS=Sac...10270     2123     100     100GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.
GO:0004222; F:metalloendopeptidase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007323; P:peptide pheromone maturation; IGI:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
2P35559    1019   IDE_RAT Insulin-degrading enzyme OS=Rattus no...9600     715     39     60GO:0009986; C:cell surface; IDA:RGD.::GO:0031597; C:cytosolic proteasome complex; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005782; C:peroxisomal matrix; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IPI:RGD.::GO:0031626; F:beta-endorphin binding; IMP:RGD.::GO:0043559; F:insulin binding; IMP:RGD.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0042447; P:hormone catabolic process; IDA:RGD.::GO:0045861; P:negative regulation of proteolysis; IDA:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:RGD.
3P14735    1019   IDE_HUMAN Insulin-degrading enzyme OS=Homo sa...9650     714     39     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
4Q24K02    1019   IDE_BOVIN Insulin-degrading enzyme OS=Bos tau...9650     714     38     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
5Q9JHR7    1019   IDE_MOUSE Insulin-degrading enzyme OS=Mus mus...9600     710     39     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6O14077    969   MU138_SCHPO Putative zinc protease mug138 OS=...9560     659     39     59GO:0005829; C:cytosol; IDA:PomBase.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase.
7P22817    990   IDE_DROME Insulin-degrading enzyme OS=Drosoph...9550     659     36     57
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8O22941    970   PXM16_ARATH Zinc-metallopeptidase, peroxisoma...9760     595     35     54GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9Q5R4H6    1152   NRDC_PONAB Nardilysin OS=Pongo abelii (Sumatr...8793e-120     403     31     50
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10O43847    1150   NRDC_HUMAN Nardilysin OS=Homo sapiens (Human)...8794e-120     402     30     50GO:0009986; C:cell surface; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.
GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007528; P:neuromuscular junction development; TAS:ProtInc.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL.
11Q8BHG1    1161   NRDC_MOUSE Nardilysin OS=Mus musculus (Mouse)...8825e-120     402     30     50GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12P47245    1161   NRDC_RAT Nardilysin OS=Rattus norvegicus (Rat...8781e-118     399     30     50
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13Q8ZMB5    962   PTRA_SALTY Protease 3 OS=Salmonella typhimuri...9411e-100     344     27     47GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14Q10040    856   YQA4_CAEEL Putative zinc protease C28F5.4 OS=...4402e-30     133     23     47
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15Q8CVS2    962   PTRA_ECOL6 Protease 3 OS=Escherichia coli O6:...9403e-100     343     27     47GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16P05458    962   PTRA_ECOLI Protease 3 OS=Escherichia coli (st...9401e-99     342     27     47GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IDA:EcoCyc.
17Q83QC3    962   PTRA_SHIFL Protease 3 OS=Shigella flexneri. G...9403e-99     340     27     47GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
18Q8X6M8    962   PTRA_ECO57 Protease 3 OS=Escherichia coli O15...9406e-99     340     27     46GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19Q8Z418    962   PTRA_SALTI Protease 3 OS=Salmonella typhi. GN...9415e-98     337     27     46GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20Q54JQ2    962   IDE_DICDI Insulin-degrading enzyme homolog OS...9239e-85     300     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21P42789    596   SDP_EIMBO Sporozoite developmental protein OS...5591e-61     225     28     48
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
22P40851    1208   AXL1_YEAST Putative protease AXL1 OS=Saccharo...1663.1     35.4     28     42GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.
GO:0004222; F:metalloendopeptidase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007120; P:axial cellular bud site selection; IMP:SGD.::GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
23Q9I2D2    775   PQQF_PSEAE Coenzyme PQQ synthesis protein F O...2022e-23     110     34     49
GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW.
24Q88A79    779   PQQF_PSESM Coenzyme PQQ synthesis protein F O...2593e-22     107     29     46
GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW.
25Q88QV3    766   PQQF_PSEPK Coenzyme PQQ synthesis protein F O...460.08     40.4     41     52
GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW.
26P55174    829   PQQF_PSEFL Coenzyme PQQ synthesis protein F O...710.47     38.1     30     44
GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW.
27P27508    761   PQQF_KLEPN Coenzyme PQQ synthesis protein F O...2074e-20     100     29     51
GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW.
28P55679    512   Y4WA_RHISN Uncharacterized zinc protease y4wA...2590.0000000000004     76.6     24     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29P31828    931   PQQL_ECOLI Probable zinc protease pqqL OS=Esc...2220.00000004     61.2     26     45
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30Q92IX7    412   Y293_RICCN Uncharacterized zinc protease RC02...2080.00000004     60.5     26     42
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31O31766    428   YMFH_BACSU Uncharacterized zinc protease ymfH...2870.0000004     57.4     24     42
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 78 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::