Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR386W
Length:
880
Number of sequences:
5887
Description:
YLR386W VAC14 SGDID:S000004378, Chr XII from 893628-896270, Genome Release 64-1-1, Verified ORF, "Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06708    880   VAC14_YEAST Vacuole morphology and inheritanc...8800     1803     100     100GO:0000306; C:extrinsic to vacuolar membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0070772; C:PAS complex; IDA:SGD.
GO:0030674; F:protein binding, bridging; IDA:SGD.
GO:0006661; P:phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0033674; P:positive regulation of kinase activity; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
2P87145    811   VAC14_SCHPO Protein VAC14 homolog OS=Schizosa...7605e-147     461     36     56GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.
GO:0046488; P:phosphatidylinositol metabolic process; NAS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0000011; P:vacuole inheritance; ISS:PomBase.
3Q5ZIW5    780   VAC14_CHICK Protein VAC14 homolog OS=Gallus g...7962e-105     350     31     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
4Q68F38    782   VAC14_XENLA Protein VAC14 homolog OS=Xenopus ...8643e-95     322     28     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
5Q80WQ2    782   VAC14_MOUSE Protein VAC14 homolog OS=Mus musc...5222e-53     202     28     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.
6Q66L58    771   VAC14_DANRE Protein VAC14 homolog OS=Danio re...3597e-51     195     34     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
7Q80W92    783   VAC14_RAT Protein VAC14 homolog OS=Rattus nor...5232e-53     202     28     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
8Q08AM6    782   VAC14_HUMAN Protein VAC14 homolog OS=Homo sap...5194e-52     199     28     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004872; F:receptor activity; NAS:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:UniProtKB.
9A2VE70    783   VAC14_BOVIN Protein VAC14 homolog OS=Bos taur...5236e-52     198     28     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
10Q9UT08    590   2AAA_SCHPO Protein phosphatase PP2A regulator...1870.78     37     25     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0000159; C:protein phosphatase type 2A complex; ISS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0019888; F:protein phosphatase regulator activity; NAS:PomBase.
GO:0030952; P:establishment or maintenance of cytoskeleton polarity; IMP:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:PomBase.::GO:0006470; P:protein dephosphorylation; ISS:PomBase.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
11P31383    635   2AAA_YEAST Protein phosphatase PP2A regulator...1945.2     34.3     23     44GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000159; C:protein phosphatase type 2A complex; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005488; F:binding; IEA:InterPro.
GO:0007015; P:actin filament organization; TAS:SGD.::GO:0007117; P:budding cell bud growth; TAS:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:SGD.::GO:0006470; P:protein dephosphorylation; TAS:SGD.::GO:0006417; P:regulation of translation; IMP:SGD.
12Q8C0Y0    875   PP4R4_MOUSE Serine/threonine-protein phosphat...1599.8     33.5     26     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
records
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