Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR378C
Length:
480
Number of sequences:
5887
Description:
YLR378C SEC61 SGDID:S000004370, Chr XII from 877178-875736, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32915    480   SC61A_YEAST Protein transport protein SEC61 O...4800     962     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005784; C:Sec61 translocon complex; IDA:SGD.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IDA:SGD.::GO:0015197; F:peptide transporter activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005048; F:signal sequence binding; IDA:SGD.
GO:0031204; P:posttranslational protein targeting to membrane, translocation; IDA:SGD.::GO:0030970; P:retrograde protein transport, ER to cytosol; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IDA:SGD.
2Q6FRY3    479   SC61A_CANGA Protein transport protein SEC61 s...4780     856     86     95GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
3Q6CPY9    480   SC61A_KLULA Protein transport protein SEC61 s...4790     818     83     92GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
4Q752H7    480   SC61A_ASHGO Protein transport protein SEC61 s...4790     813     82     92GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
5Q96TW8    479   SC61A_HANAN Protein transport protein SEC61 s...4780     743     74     87GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
6Q9P8E3    479   SC61A_CANAL Protein transport protein SEC61 s...4780     676     68     82GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:CGD.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
7P78979    471   SC61A_YARLI Protein transport protein SEC61 s...4660     674     70     84GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
8Q6BN08    479   SC61A_DEBHA Protein transport protein SEC61 s...4780     673     69     84GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
9Q870W0    476   SC61A_NEUCR Protein transport protein SEC61 s...4660     624     64     80GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
10Q54XK2    475   SC61A_DICDI Protein transport protein Sec61 s...4620     550     56     73GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; ISS:UniProtKB.
GO:0031204; P:posttranslational protein targeting to membrane, translocation; ISS:UniProtKB.
11Q8AY31    476   SC61A_BOVVA Protein transport protein Sec61 s...4630     531     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
12Q90ZM2    476   S61A1_DANRE Protein transport protein Sec61 s...4630     530     57     75GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0021986; P:habenula development; IMP:ZFIN.
13Q98SN8    476   S61A2_ONCMY Protein transport protein Sec61 s...4630     530     58     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
14Q90YL4    476   S61A2_DANRE Protein transport protein Sec61 s...4630     530     57     75GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
15Q7T278    476   SC61A_HARAN Protein transport protein Sec61 s...4630     529     57     75GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
16Q7T277    476   SC61A_DISMA Protein transport protein Sec61 s...4630     529     57     75GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
17Q8AY36    476   SC61A_PAGBO Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
18Q8AY35    476   SC61A_NOTAN Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
19Q8AY32    476   SC61A_GADOC Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
20P61621    476   S61A1_RAT Protein transport protein Sec61 sub...4630     528     57     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0019718; C:rough microsome; IDA:RGD.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0034341; P:response to interferon-gamma; IEP:RGD.
21Q5R5L5    476   S61A1_PONAB Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
22P61620    476   S61A1_MOUSE Protein transport protein Sec61 s...4630     528     57     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.::GO:0043022; F:ribosome binding; IDA:MGI.
23P61619    476   S61A1_HUMAN Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
24Q98SN9    476   S61A1_ONCMY Protein transport protein Sec61 s...4630     528     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
25P38377    476   S61A1_CANFA Protein transport protein Sec61 s...4630     526     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; IDA:UniProtKB.
26P79088    479   SC61A_SCHPO Protein transport protein sec61 s...4720     525     58     74GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005784; C:Sec61 translocon complex; ISS:PomBase.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.::GO:0043022; F:ribosome binding; NAS:PomBase.
GO:0006620; P:posttranslational protein targeting to membrane; ISS:PomBase.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; ISS:PomBase.
27Q8AY33    476   SC61A_BORSA Protein transport protein Sec61 s...4630     525     57     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
28Q9JLR1    476   S61A2_MOUSE Protein transport protein Sec61 s...4620     525     56     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.::GO:0043022; F:ribosome binding; IDA:MGI.
29Q9H9S3    476   S61A2_HUMAN Protein transport protein Sec61 s...4620     525     56     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
30Q2KHX4    476   S61A2_BOVIN Protein transport protein Sec61 s...4620     525     56     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
31Q5EA68    476   S61A1_BOVIN Protein transport protein Sec61 s...4630     525     56     74GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
records
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