UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR377C

Length:

348

Number of sequences:

5887

Description:

YLR377C FBP1 SGDID:S000004369, Chr XII from 874792-873746, Genome Release 64-1-1, reverse complement, Verified ORF, "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P09201	348	F16P_YEAST Fructose-1,6-bisphosphatase OS=Sac...	348	0	721	100	100	GO:0005829; C:cytosol; IDA:SGD.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006094; P:gluconeogenesis; IMP:SGD.::GO:0072593; P:reactive oxygen species metabolic process; IMP:SGD.
2	Q05079	355	F16P_KLULA Fructose-1,6-bisphosphatase OS=126...	348	0	551	76	86
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
3	P09202	347	F16P_SCHPO Fructose-1,6-bisphosphatase OS=Sch...	350	1e-147	427	60	78	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0044262; P:cellular carbohydrate metabolic process; NAS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.
4	Q0JHF8	339	F16P2_ORYSJ Fructose-1,6-bisphosphatase, cyto...	329	7e-119	353	53	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
5	A2WXB2	339	F16P2_ORYSI Fructose-1,6-bisphosphatase, cyto...	329	7e-119	353	53	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
6	Q9SDL8	344	F16P2_ORYCO Fructose-1,6-bisphosphatase, cyto...	329	2e-118	353	53	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
7	Q43139	343	F16P2_SACHY Fructose-1,6-bisphosphatase, cyto...	324	9e-117	348	52	73	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
8	Q9MA79	341	F16P2_ARATH Fructose-1,6-bisphosphatase, cyto...	323	4e-116	347	54	71	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IDA:TAIR.::GO:0015979; P:photosynthesis; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009750; P:response to fructose stimulus; IMP:TAIR.::GO:0005983; P:starch catabolic process; IMP:TAIR.::GO:0005986; P:sucrose biosynthetic process; IMP:TAIR.
9	P46267	339	F16P2_BRANA Fructose-1,6-bisphosphatase, cyto...	322	6e-114	341	52	70	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
10	P14766	341	F16P2_SPIOL Fructose-1,6-bisphosphatase, cyto...	322	6e-114	341	51	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
11	Q9XF47	341	F16P2_MUSAC Fructose-1,6-bisphosphatase, cyto...	328	1e-113	340	51	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
12	Q42649	341	F16P2_BETVU Fructose-1,6-bisphosphatase, cyto...	322	1e-113	340	52	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
13	P46276	340	F16P2_SOLTU Fructose-1,6-bisphosphatase, cyto...	324	3e-112	337	51	70	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
14	Q8RW99	341	F16P2_PEA Fructose-1,6-bisphosphatase, cytoso...	322	6e-111	333	50	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
15	P00637	338	F16P1_RABIT Fructose-1,6-bisphosphatase 1 OS=...	328	1e-102	312	49	69	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
16	Q3SZB7	338	F16P1_BOVIN Fructose-1,6-bisphosphatase 1 OS=...	329	3e-101	309	47	70	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
17	P00636	338	F16P1_PIG Fructose-1,6-bisphosphatase 1 OS=Su...	329	4e-101	308	48	69	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
18	Q051E1	342	F16PA_LEPBL Fructose-1,6-bisphosphatase class...	332	7e-100	305	48	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
19	Q04T19	342	F16PA_LEPBJ Fructose-1,6-bisphosphatase class...	332	7e-100	305	48	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
20	B3QWF5	349	F16PA_CHLT3 Fructose-1,6-bisphosphatase class...	322	2e-99	305	48	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-KW.
21	P09199	337	F16P1_SHEEP Fructose-1,6-bisphosphatase 1 OS=...	328	2e-99	304	47	70	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
22	Q8F421	342	F16PA_LEPIN Fructose-1,6-bisphosphatase class...	332	3e-99	303	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
23	Q72RN8	342	F16PA_LEPIC Fructose-1,6-bisphosphatase class...	332	3e-99	303	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
24	B0SQL1	343	F16PA_LEPBP Fructose-1,6-bisphosphatase class...	336	5e-99	303	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
25	B0SHG0	343	F16PA_LEPBA Fructose-1,6-bisphosphatase class...	336	5e-99	303	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
26	Q9Z1N1	339	F16P2_RAT Fructose-1,6-bisphosphatase isozyme...	334	6e-98	300	45	67
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006094; P:gluconeogenesis; IDA:RGD.
27	P70695	339	F16P2_MOUSE Fructose-1,6-bisphosphatase isozy...	334	1e-97	299	45	67
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
28	P19112	363	F16P1_RAT Fructose-1,6-bisphosphatase 1 OS=Ra...	334	2e-97	300	46	68	GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:RGD.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; IDA:RGD.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; IDA:RGD.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
29	Q9QXD6	338	F16P1_MOUSE Fructose-1,6-bisphosphatase 1 OS=...	329	2e-96	296	46	69	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; ISS:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
									GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; ISS:UniProtKB.::GO:0006094; P:gluconeogenesis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
30	Q2S8D3	336	F16PA_HAHCH Fructose-1,6-bisphosphatase class...	334	4e-96	295	45	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
31	P09467	338	F16P1_HUMAN Fructose-1,6-bisphosphatase 1 OS=...	327	6e-96	295	48	69	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0016208; F:AMP binding; IDA:UniProtKB.::GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IMP:UniProtKB.::GO:0048029; F:monosaccharide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; IDA:UniProtKB.::GO:0006002; P:fructose 6-phosphate metabolic process; IDA:UniProtKB.::GO:0006094; P:gluconeogenesis; IMP:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; IDA:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0006111; P:regulation of gluconeogenesis; IMP:UniProtKB.

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