rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q5DU57 | 656 | SPT13_MOUSE Spermatogenesis-associated protei... | 261 | 0.0004 | 48.5 | 22 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 92 | Q54EH3 | 1031 | Y1510_DICDI GTPase-activating protein DDB_G02... | 115 | 0.0004 | 48.5 | 23 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 93 | O54874 | 1732 | MRCKA_RAT Serine/threonine-protein kinase MRC... | 149 | 0.0004 | 48.9 | 21 | 45 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IDA:UniProtKB. | 94 | Q6DT37 | 1551 | MRCKG_HUMAN Serine/threonine-protein kinase M... | 178 | 0.0004 | 48.5 | 25 | 39 | GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 95 | Q9H8V3 | 914 | ECT2_HUMAN Protein ECT2 OS=Homo sapiens (Huma... | 201 | 0.0005 | 48.5 | 27 | 42 | GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IMP:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0070830; P:tight junction assembly; IMP:UniProtKB. | 96 | P49025 | 2055 | CTRO_MOUSE Citron Rho-interacting kinase OS=M... | 133 | 0.0005 | 48.5 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0048699; P:generation of neurons; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; IDA:UniProtKB. | 97 | P91621 | 2072 | SIF1_DROME Protein still life, isoform SIF ty... | 231 | 0.0006 | 48.1 | 23 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase. | 98 | Q3UU96 | 1719 | MRCKA_MOUSE Serine/threonine-protein kinase M... | 149 | 0.0006 | 48.1 | 21 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.::GO:0007097; P:nuclear migration; IMP:MGI. | 99 | Q8TCU6 | 1659 | PREX1_HUMAN Phosphatidylinositol 3,4,5-trisph... | 269 | 0.0008 | 47.8 | 23 | 45 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0005886; C:plasma membrane; TAS:UniProtKB. | | | | | | | | | | GO:0019899; F:enzyme binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; TAS:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042119; P:neutrophil activation; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006801; P:superoxide metabolic process; TAS:UniProtKB. | 100 | Q63406 | 1149 | MCF2L_RAT Guanine nucleotide exchange factor ... | 209 | 0.0008 | 47.8 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 101 | Q54C71 | 1125 | KXCB_DICDI Kinase and exchange factor for Rac... | 303 | 0.001 | 47.4 | 20 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 102 | P91620 | 2061 | SIF2_DROME Protein still life, isoforms C/SIF... | 231 | 0.001 | 47.8 | 23 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase. | 103 | Q64096 | 1149 | MCF2L_MOUSE Guanine nucleotide exchange facto... | 208 | 0.001 | 47 | 25 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 104 | A1IGU4 | 676 | ARH37_MOUSE Rho guanine nucleotide exchange f... | 216 | 0.002 | 45.8 | 24 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 105 | Q80UW5 | 1551 | MRCKG_MOUSE Serine/threonine-protein kinase M... | 176 | 0.003 | 46.2 | 24 | 40 | GO:0031252; C:cell leading edge; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 106 | Q5VT25 | 1732 | MRCKA_HUMAN Serine/threonine-protein kinase M... | 129 | 0.003 | 46.2 | 21 | 44 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 107 | A1L390 | 1219 | PKHG3_HUMAN Pleckstrin homology domain-contai... | 176 | 0.003 | 45.8 | 26 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 108 | Q6ZPF3 | 1715 | TIAM2_MOUSE T-lymphoma invasion and metastasi... | 205 | 0.003 | 45.8 | 20 | 45 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 109 | Q4VAC9 | 1341 | PKHG3_MOUSE Pleckstrin homology domain-contai... | 274 | 0.004 | 45.8 | 24 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 110 | Q8IVF5 | 1701 | TIAM2_HUMAN T-lymphoma invasion and metastasi... | 205 | 0.004 | 45.4 | 20 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 111 | Q8R0J1 | 787 | PKHG6_MOUSE Pleckstrin homology domain-contai... | 215 | 0.005 | 45.1 | 22 | 44 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 112 | Q5RDK0 | 564 | ARHG9_PONAB Rho guanine nucleotide exchange f... | 267 | 0.006 | 44.7 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 113 | O15068 | 1137 | MCF2L_HUMAN Guanine nucleotide exchange facto... | 191 | 0.008 | 44.7 | 24 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 114 | Q54B37 | 1155 | GXCJ_DICDI RhoGEF domain-containing protein g... | 278 | 0.01 | 44.3 | 23 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 115 | P40995 | 872 | SCD1_SCHPO Rho guanine nucleotide exchange fa... | 200 | 0.012 | 43.9 | 23 | 49 | GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0043332; C:mating projection tip; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005819; C:spindle; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:PomBase. | | | | | | | | | | GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032955; P:regulation of barrier septum assembly; IGI:PomBase.::GO:0043088; P:regulation of Cdc42 GTPase activity; TAS:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0030100; P:regulation of endocytosis; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0032887; P:regulation of spindle elongation; IMP:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase. | 116 | Q58DL7 | 561 | ARHG9_BOVIN Rho guanine nucleotide exchange f... | 267 | 0.014 | 43.5 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 117 | Q55E26 | 1198 | GXCB_DICDI Rac guanine nucleotide exchange fa... | 272 | 0.025 | 42.7 | 22 | 44 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005770; C:late endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0051764; P:actin crosslink formation; IDA:dictyBase.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 118 | Q9QX73 | 493 | ARHG9_RAT Rho guanine nucleotide exchange fac... | 195 | 0.028 | 42.4 | 23 | 46 | GO:0005938; C:cell cortex; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043113; P:receptor clustering; IDA:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 119 | Q3UTH8 | 516 | ARHG9_MOUSE Rho guanine nucleotide exchange f... | 267 | 0.029 | 42.4 | 22 | 43 | GO:0005938; C:cell cortex; TAS:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI. | 120 | O43307 | 516 | ARHG9_HUMAN Rho guanine nucleotide exchange f... | 267 | 0.033 | 42 | 22 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0034220; P:ion transmembrane transport; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 121 | P52734 | 960 | FGD1_MOUSE FYVE, RhoGEF and PH domain-contain... | 129 | 0.08 | 41.2 | 25 | 43 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IDA:UniProtKB. |