Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR359W
Length:
482
Number of sequences:
5887
Description:
YLR359W ADE13 SGDID:S000004351, Chr XII from 844282-845730, Genome Release 64-1-1, Verified ORF, "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q05911    482   PUR8_YEAST Adenylosuccinate lyase OS=Saccharo...4820     999     100     100
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IMP:SGD.
GO:0006189; P:'de novo' IMP biosynthetic process; IMP:SGD.
2O60105    482   PUR8_SCHPO Adenylosuccinate lyase OS=Schizosa...4820     721     71     83GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; ISS:PomBase.
GO:0006189; P:'de novo' IMP biosynthetic process; ISS:PomBase.
3P21265    485   PUR8_CHICK Adenylosuccinate lyase OS=Gallus g...4680     637     66     79GO:0005829; C:cytosol; TAS:Reactome.
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0006189; P:'de novo' IMP biosynthetic process; TAS:Reactome.::GO:0006167; P:AMP biosynthetic process; TAS:Reactome.::GO:0006144; P:purine base metabolic process; TAS:Reactome.
4P54822    484   PUR8_MOUSE Adenylosuccinate lyase OS=Mus musc...4650     632     65     80GO:0005739; C:mitochondrion; IDA:MGI.
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
5P30566    484   PUR8_HUMAN Adenylosuccinate lyase OS=Homo sap...4700     629     64     79GO:0005829; C:cytosol; TAS:Reactome.
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IDA:UniProtKB.
GO:0006167; P:AMP biosynthetic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0006144; P:purine base metabolic process; TAS:Reactome.
6Q8HXY5    484   PUR8_MACFA Adenylosuccinate lyase OS=Macaca f...4700     627     64     79
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
7A3KN12    490   PUR8_BOVIN Adenylosuccinate lyase OS=Bos taur...4710     620     63     79
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
8Q60Q90    478   PUR8_CAEBR Adenylosuccinate lyase OS=Caenorha...4852e-126     383     43     61
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
9Q21774    478   PUR8_CAEEL Adenylosuccinate lyase OS=Caenorha...4877e-126     382     43     61
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006997; P:nucleus organization; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
10Q9UZ99    450   PUR8_PYRAB Adenylosuccinate lyase OS=Pyrococc...4522e-55     197     31     51
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
11O58582    450   PUR8_PYRHO Adenylosuccinate lyase OS=NBRC 100...4545e-52     187     30     50
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
12O28041    444   PUR8_ARCFU Adenylosuccinate lyase OS=9628 / N...3901e-47     176     33     53
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
13Q58339    462   PUR8_METJA Adenylosuccinate lyase OS=JCM 1004...4552e-46     172     29     49
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
14O27580    449   PUR8_METTH Adenylosuccinate lyase OS=thermoau...4565e-46     171     27     49
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
15P12047    431   PUR8_BACSU Adenylosuccinate lyase OS=Bacillus...3969e-46     170     30     51
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IDA:MGI.
GO:0006167; P:AMP biosynthetic process; IDA:MGI.
16Q49YV3    431   PUR8_STAS1 Adenylosuccinate lyase OS=DSM 2022...4287e-44     165     29     49
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
17Q7A0G9    431   PUR8_STAAW Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
18Q6G825    431   PUR8_STAAS Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
19Q6GFE9    431   PUR8_STAAR Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
20Q7A4Q3    431   PUR8_STAAN Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
21Q99SX9    431   PUR8_STAAM Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
22Q5HEL4    431   PUR8_STAAC Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
23Q2YU66    431   PUR8_STAAB Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
24Q2G2S0    431   PUR8_STAA8 Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
25Q2FFI7    431   PUR8_STAA3 Adenylosuccinate lyase OS=Staphylo...4343e-43     163     29     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
26O66856    437   PUR8_AQUAE Adenylosuccinate lyase OS=Aquifex ...3963e-42     160     29     49
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
27Q8CRT6    431   PUR8_STAES Adenylosuccinate lyase OS=Staphylo...4287e-42     159     28     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
28Q5HN26    431   PUR8_STAEQ Adenylosuccinate lyase OS=Staphylo...4287e-42     159     28     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
29Q4L7M3    431   PUR8_STAHJ Adenylosuccinate lyase OS=Staphylo...3907e-41     156     28     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
30P72478    432   PUR8_STRMU Adenylosuccinate lyase OS=Streptoc...3977e-39     150     28     48
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
31P74384    431   PUR8_SYNY3 Adenylosuccinate lyase OS=Synechoc...4344e-38     148     27     49
GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
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