UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR359W

Length:

482

Number of sequences:

5887

Description:

YLR359W ADE13 SGDID:S000004351, Chr XII from 844282-845730, Genome Release 64-1-1, Verified ORF, "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P74384	431	PUR8_SYNY3 Adenylosuccinate lyase OS=Synechoc...	434	4e-38	148	27	49
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
32	Q9X0I0	431	PUR8_THEMA Adenylosuccinate lyase OS=Thermoto...	451	2e-37	147	26	47
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
33	Q9RSE6	435	PUR8_DEIRA Adenylosuccinate lyase OS=LMG 4051...	385	2e-37	146	28	46
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
34	P56468	440	PUR8_HELPY Adenylosuccinate lyase OS=pylori)....	386	1e-32	132	26	48
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
35	Q9ZKA2	440	PUR8_HELPJ Adenylosuccinate lyase OS=Helicoba...	386	5e-31	127	26	47
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
36	O42889	447	YBN5_SCHPO Uncharacterized protein C8E4.05c O...	461	2e-20	97.4	25	43	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0003824; F:catalytic activity; IEA:InterPro.
									GO:0033554; P:cellular response to stress; IEP:PomBase.
37	Q59092	451	PCAB_ACIAD 3-carboxy-cis,cis-muconate cyclois...	368	1e-17	88.6	26	44
									GO:0047472; F:3-carboxy-cis,cis-muconate cycloisomerase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0019619; P:protocatechuate catabolic process; IEA:InterPro.
38	Q89AM3	460	PUR8_BUCBP Adenylosuccinate lyase OS=Buchnera...	344	0.0000000007	64.7	24	42
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
39	P57351	456	PUR8_BUCAI Adenylosuccinate lyase OS=(Acyrtho...	369	0.000000002	63.2	23	43
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
40	O31385	451	PCAB_BRAJA 3-carboxy-cis,cis-muconate cyclois...	366	0.000000003	62.8	23	40
									GO:0047472; F:3-carboxy-cis,cis-muconate cycloisomerase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0019619; P:protocatechuate catabolic process; IEA:InterPro.
41	P32427	422	PCAB_PSEPU 3-carboxy-cis,cis-muconate cyclois...	235	0.000000009	60.8	28	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0047472; F:3-carboxy-cis,cis-muconate cycloisomerase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0019619; P:protocatechuate catabolic process; IEA:InterPro.
42	Q54J34	466	PUR8_DICDI Adenylosuccinate lyase OS=Dictyost...	291	0.00000002	60.5	23	41
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; ISS:dictyBase.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
43	Q8K9Q7	456	PUR8_BUCAP Adenylosuccinate lyase OS=Buchnera...	348	0.00000003	59.3	24	41
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
44	P44797	456	PUR8_HAEIN Adenylosuccinate lyase OS=Haemophi...	234	0.00000004	59.3	25	43
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
45	Q8Y551	455	FUMC_LISMO Fumarate hydratase class II OS=Lis...	279	0.0000002	57	28	43	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
46	P0AB89	456	PUR8_ECOLI Adenylosuccinate lyase OS=Escheric...	346	0.0000002	57	23	40
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IDA:EcoCyc.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
47	P0AB90	456	PUR8_ECOL6 Adenylosuccinate lyase OS=Escheric...	346	0.0000002	57	23	40
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
48	Q71XE0	455	FUMC_LISMF Fumarate hydratase class II OS=Lis...	279	0.0000006	55.5	29	43	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
49	Q929E8	455	FUMC_LISIN Fumarate hydratase class II OS=Lis...	278	0.000001	54.3	26	43	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
50	Q7VKC9	464	FUMC_HAEDU Fumarate hydratase class II OS=Hae...	328	0.000003	53.1	24	44	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
51	Q8FQP8	473	FUMC_COREF Fumarate hydratase class II OS=111...	248	0.000008	51.6	28	41	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
52	Q7SX99	509	FUMH_DANRE Fumarate hydratase, mitochondrial ...	252	0.00001	51.2	24	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
53	Q8Z6R6	467	FUMC_SALTI Fumarate hydratase class II OS=Sal...	188	0.00001	51.2	29	44	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
54	Q9I0K9	456	PUR8_PSEAE Adenylosuccinate lyase OS=12228). ...	267	0.00001	51.2	23	41
									GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:EC.::GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IEA:EC.
									GO:0006188; P:IMP biosynthetic process; IEA:InterPro.
55	Q8ZPL7	467	FUMC_SALTY Fumarate hydratase class II OS=Sal...	188	0.00001	51.2	29	44	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
56	A6KYN9	446	ARLY_BACV8 Argininosuccinate lyase OS=Bactero...	155	0.00001	50.8	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004056; F:argininosuccinate lyase activity; IEA:EC.
									GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
57	P07343	462	FUMC_BACSU Fumarate hydratase class II OS=Bac...	331	0.00001	50.8	24	43	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
58	Q7N4H8	464	FUMC_PHOLL Fumarate hydratase class II OS=Pho...	195	0.00002	50.8	29	43	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
59	Q9CMK1	464	FUMC_PASMU Fumarate hydratase class II OS=Pas...	337	0.00003	50.1	24	41	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
60	Q83ML8	467	FUMC_SHIFL Fumarate hydratase class II OS=Shi...	189	0.00008	48.5	27	44	GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
61	O17214	501	FUMH_CAEEL Probable fumarate hydratase, mitoc...	253	0.00008	48.9	27	43	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
									GO:0004333; F:fumarate hydratase activity; IEA:EC.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006106; P:fumarate metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.

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