rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q06143 | 298 | DIC1_YEAST Mitochondrial dicarboxylate transp... | 298 | 0 | 619 | 100 | 100 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005310; F:dicarboxylic acid transmembrane transporter activity; IDA:SGD. | | | | | | | | | | GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW. | 2 | Q6FTN2 | 295 | DIC1_CANGA Mitochondrial dicarboxylate transp... | 291 | 1e-160 | 456 | 74 | 85 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW. | 3 | Q9UBX3 | 287 | DIC_HUMAN Mitochondrial dicarboxylate carrier... | 275 | 8e-58 | 193 | 40 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005310; F:dicarboxylic acid transmembrane transporter activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0006811; P:ion transport; TAS:Reactome.::GO:0006839; P:mitochondrial transport; IEA:InterPro.::GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome. | 4 | Q9QZD8 | 287 | DIC_MOUSE Mitochondrial dicarboxylate carrier... | 277 | 3e-57 | 191 | 39 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 5 | Q54PY7 | 318 | M2OM_DICDI Probable mitochondrial 2-oxoglutar... | 278 | 8e-55 | 186 | 41 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005310; F:dicarboxylic acid transmembrane transporter activity; ISS:dictyBase. | | | | | | | | | | | 6 | Q9CR62 | 314 | M2OM_MOUSE Mitochondrial 2-oxoglutarate/malat... | 290 | 3e-51 | 177 | 39 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | | 7 | Q02978 | 314 | M2OM_HUMAN Mitochondrial 2-oxoglutarate/malat... | 290 | 8e-51 | 176 | 39 | 55 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005743; C:mitochondrial inner membrane; TAS:Reactome. | | | | | | | | | | GO:0015367; F:oxoglutarate:malate antiporter activity; TAS:Reactome. | | | | | | | | | | GO:0006094; P:gluconeogenesis; TAS:Reactome. | 8 | P22292 | 314 | M2OM_BOVIN Mitochondrial 2-oxoglutarate/malat... | 290 | 3e-50 | 174 | 38 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; ISS:AgBase. | | | | | | | | | | | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 9 | P97700 | 314 | M2OM_RAT Mitochondrial 2-oxoglutarate/malate ... | 290 | 9e-48 | 167 | 38 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; IMP:RGD. | | | | | | | | | | | 10 | P04633 | 307 | UCP1_RAT Mitochondrial brown fat uncoupling p... | 284 | 5e-41 | 150 | 33 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; TAS:RGD. | | | | | | | | | | GO:0017077; F:oxidative phosphorylation uncoupler activity; IDA:RGD. | | | | | | | | | | GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0006091; P:generation of precursor metabolites and energy; TAS:RGD.::GO:0006839; P:mitochondrial transport; IDA:RGD.::GO:0044253; P:positive regulation of multicellular organismal metabolic process; TAS:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD. | 11 | Q9ER18 | 307 | UCP1_PHOSU Mitochondrial brown fat uncoupling... | 284 | 3e-40 | 148 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 12 | P56501 | 308 | UCP3_MOUSE Mitochondrial uncoupling protein 3... | 196 | 0.001 | 43.5 | 23 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017077; F:oxidative phosphorylation uncoupler activity; IMP:MGI. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IMP:MGI.::GO:0006839; P:mitochondrial transport; IEA:InterPro.::GO:0000303; P:response to superoxide; IMP:MGI. | 13 | P25874 | 307 | UCP1_HUMAN Mitochondrial brown fat uncoupling... | 281 | 4e-40 | 147 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0050873; P:brown fat cell differentiation; ISS:HGNC.::GO:0022904; P:respiratory electron transport chain; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 14 | P12242 | 307 | UCP1_MOUSE Mitochondrial brown fat uncoupling... | 284 | 4e-40 | 147 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017077; F:oxidative phosphorylation uncoupler activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0050873; P:brown fat cell differentiation; IEP:HGNC.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 15 | P56499 | 308 | UCP3_RAT Mitochondrial uncoupling protein 3 O... | 196 | 0.002 | 42.4 | 23 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015078; F:hydrogen ion transmembrane transporter activity; TAS:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0006839; P:mitochondrial transport; IEA:InterPro.::GO:0014823; P:response to activity; IEP:RGD.::GO:0009409; P:response to cold; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IDA:HGNC.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0000303; P:response to superoxide; IDA:RGD. | 16 | O97562 | 309 | UCP2_PIG Mitochondrial uncoupling protein 2 O... | 205 | 0.00001 | 49.7 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 17 | A0PC02 | 306 | UCP1_OCHDA Mitochondrial brown fat uncoupling... | 181 | 0.006 | 41.2 | 23 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 18 | B0G143 | 294 | UCPB_DICDI Mitochondrial substrate carrier fa... | 289 | 5e-39 | 144 | 30 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 19 | Q9N2J1 | 309 | UCP2_CANFA Mitochondrial uncoupling protein 2... | 205 | 0.00003 | 48.1 | 27 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 20 | P04575 | 307 | UCP1_MESAU Mitochondrial brown fat uncoupling... | 284 | 6e-39 | 144 | 32 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 21 | P56500 | 309 | UCP2_RAT Mitochondrial uncoupling protein 2 O... | 205 | 0.000001 | 52.4 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0006839; P:mitochondrial transport; IDA:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0000303; P:response to superoxide; IDA:RGD. | 22 | Q9N2I9 | 311 | UCP3_CANFA Mitochondrial uncoupling protein 3... | 189 | 0.00006 | 47.4 | 25 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 23 | Q9W725 | 310 | UCP2_CYPCA Mitochondrial uncoupling protein 2... | 188 | 0.0007 | 44.3 | 24 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 24 | P70406 | 309 | UCP2_MOUSE Mitochondrial uncoupling protein 2... | 205 | 0.000001 | 52.4 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 25 | Q9W720 | 310 | UCP2_DANRE Mitochondrial uncoupling protein 2... | 188 | 0.00004 | 47.8 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 26 | Q8K404 | 307 | UCP1_DICGR Mitochondrial brown fat uncoupling... | 127 | 0.023 | 39.3 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 27 | P14271 | 306 | UCP1_RABIT Mitochondrial brown fat uncoupling... | 281 | 3e-38 | 142 | 31 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 28 | O77792 | 311 | UCP3_BOVIN Mitochondrial uncoupling protein 3... | 86 | 0.025 | 39.3 | 26 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 29 | Q3SZI5 | 309 | UCP2_BOVIN Mitochondrial uncoupling protein 2... | 205 | 0.000009 | 50.1 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 30 | O97649 | 308 | UCP3_PIG Mitochondrial uncoupling protein 3 O... | 85 | 0.15 | 37 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro. | 31 | P55916 | 312 | UCP3_HUMAN Mitochondrial uncoupling protein 3... | 295 | 9e-38 | 141 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0006839; P:mitochondrial transport; IEA:InterPro.::GO:0022904; P:respiratory electron transport chain; TAS:Reactome.::GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc. |