rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q06142 | 861 | IMB1_YEAST Importin subunit beta-1 OS=Sacchar... | 861 | 0 | 1769 | 100 | 100 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:SGD. | | | | | | | | | | GO:0051292; P:nuclear pore complex assembly; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD. | 2 | O13864 | 863 | IMB1_SCHPO Importin subunit beta-1 OS=Schizos... | 858 | 0 | 614 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IMP:PomBase.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 3 | O18388 | 884 | IMB_DROME Importin subunit beta OS=Drosophila... | 888 | 2e-151 | 474 | 33 | 54 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 4 | P70168 | 876 | IMB1_MOUSE Importin subunit beta-1 OS=Mus mus... | 879 | 4e-149 | 468 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0008565; F:protein transporter activity; IDA:MGI. | | | | | | | | | | GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI. | 5 | Q14974 | 876 | IMB1_HUMAN Importin subunit beta-1 OS=Homo sa... | 879 | 9e-148 | 464 | 34 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome. | 6 | P52296 | 875 | IMB1_RAT Importin subunit beta-1 OS=Rattus no... | 879 | 8e-144 | 454 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 7 | O60100 | 1067 | IMB4_SCHPO Probable importin subunit beta-4 O... | 667 | 0.00000000002 | 72 | 21 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 8 | Q54EW3 | 1067 | IPO5_DICDI Probable importin-5 homolog OS=Dic... | 215 | 0.79 | 37.4 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 9 | O14089 | 910 | IMB2_SCHPO Importin subunit beta-2 OS=Schizos... | 124 | 0.35 | 38.1 | 27 | 48 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; NAS:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 10 | Q55CQ7 | 931 | TNPO_DICDI Transportin OS=Dictyostelium disco... | 472 | 0.000006 | 53.9 | 22 | 40 | GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; ISS:dictyBase. | 11 | O74476 | 1095 | IMB3_SCHPO Importin subunit beta-3 OS=Schizos... | 158 | 0.0002 | 49.3 | 23 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 12 | P38217 | 918 | IMB2_YEAST Importin subunit beta-2 OS=Sacchar... | 128 | 0.00006 | 50.4 | 23 | 48 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IPI:SGD. | | | | | | | | | | GO:0007049; P:cell cycle; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; IDA:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD. | 13 | P42345 | 2549 | MTOR_HUMAN Serine/threonine-protein kinase mT... | 381 | 0.02 | 42.4 | 20 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB. | 14 | Q91YE6 | 1041 | IPO9_MOUSE Importin-9 OS=Mus musculus (Mouse)... | 130 | 0.058 | 40.8 | 25 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 15 | Q96P70 | 1041 | IPO9_HUMAN Importin-9 OS=Homo sapiens (Human)... | 130 | 0.059 | 40.8 | 25 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008565; F:protein transporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0006606; P:protein import into nucleus; NAS:UniProtKB. | 16 | Q8VI75 | 1082 | IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)... | 291 | 0.19 | 39.3 | 19 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 17 | Q9ZPY7 | 972 | XPO2_ARATH Exportin-2 OS=Arabidopsis thaliana... | 130 | 0.26 | 38.9 | 29 | 46 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 18 | Q8TEX9 | 1081 | IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)... | 291 | 0.56 | 37.7 | 19 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 19 | P42346 | 2549 | MTOR_RAT Serine/threonine-protein kinase mTOR... | 389 | 0.68 | 37.4 | 20 | 37 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD. | 20 | Q9JLN9 | 2549 | MTOR_MOUSE Serine/threonine-protein kinase mT... | 381 | 0.89 | 37 | 20 | 37 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI. | 21 | Q9SLX0 | 534 | IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryz... | 59 | 0.9 | 37 | 34 | 49 | GO:0005634; C:nucleus; IEA:InterPro.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IEA:InterPro. | 22 | Q54WR2 | 2667 | GCN1L_DICDI Translational activator gcn1 OS=D... | 435 | 1 | 37 | 22 | 41 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006448; P:regulation of translational elongation; ISS:dictyBase. | 23 | O04294 | 531 | IMA2_ARATH Importin subunit alpha-2 OS=Arabid... | 97 | 1.7 | 35.8 | 30 | 46 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IMP:TAIR.::GO:0006606; P:protein import into nucleus; IEA:InterPro. | 24 | Q86C65 | 2380 | TOR_DICDI Target of rapamycin OS=Dictyosteliu... | 102 | 2.2 | 35.8 | 27 | 40 | GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 25 | Q8BIV3 | 1105 | RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc... | 450 | 3 | 35.4 | 20 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 26 | P30154 | 601 | 2AAB_HUMAN Serine/threonine-protein phosphata... | 118 | 4 | 34.7 | 24 | 45 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB. | 27 | P32337 | 1089 | IMB3_YEAST Importin subunit beta-3 OS=Sacchar... | 192 | 4.5 | 34.7 | 25 | 45 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD. | | | | | | | | | | GO:0006406; P:mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD. | 28 | Q71VM4 | 526 | IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryz... | 114 | 4.8 | 34.3 | 25 | 40 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006606; P:protein import into nucleus; IEA:InterPro. | 29 | Q7TNP2 | 601 | 2AAB_MOUSE Serine/threonine-protein phosphata... | 118 | 4.9 | 34.3 | 24 | 45 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 30 | Q5DU56 | 1064 | NLRC3_MOUSE Protein NLRC3 OS=Mus musculus (Mo... | 99 | 5.3 | 34.7 | 27 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042110; P:T cell activation; ISS:UniProtKB. | 31 | Q4QQT4 | 601 | 2AAB_RAT Serine/threonine-protein phosphatase... | 118 | 6.2 | 34.3 | 24 | 45 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | |