Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List


UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR347C
Length:
861
Number of sequences:
5887
Description:
YLR347C KAP95 SGDID:S000004339, Chr XII from 826413-823828, Genome Release 64-1-1, reverse complement, Verified ORF, "Karyopherin beta, forms a complex with Srp1p/Kap60p; interacts with nucleoporins to mediate nuclear import of NLS-containing cargo proteins via the nuclear pore complex; regulates PC biosynthesis; GDP-to-GTP exchange factor for Gsp1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06142    861   IMB1_YEAST Importin subunit beta-1 OS=Sacchar...8610     1769     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0051292; P:nuclear pore complex assembly; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD.
2O13864    863   IMB1_SCHPO Importin subunit beta-1 OS=Schizos...8580     614     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0051301; P:cell division; IMP:PomBase.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
3O18388    884   IMB_DROME Importin subunit beta OS=Drosophila...8882e-151     474     33     54GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
4P70168    876   IMB1_MOUSE Importin subunit beta-1 OS=Mus mus...8794e-149     468     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI.
GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI.
5Q14974    876   IMB1_HUMAN Importin subunit beta-1 OS=Homo sa...8799e-148     464     34     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome.
6P52296    875   IMB1_RAT Importin subunit beta-1 OS=Rattus no...8798e-144     454     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
7O60100    1067   IMB4_SCHPO Probable importin subunit beta-4 O...6670.00000000002     72     21     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
8Q54EW3    1067   IPO5_DICDI Probable importin-5 homolog OS=Dic...2150.79     37.4     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
9O14089    910   IMB2_SCHPO Importin subunit beta-2 OS=Schizos...1240.35     38.1     27     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; NAS:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
10Q55CQ7    931   TNPO_DICDI Transportin OS=Dictyostelium disco...4720.000006     53.9     22     40GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase.
GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; ISS:dictyBase.
11O74476    1095   IMB3_SCHPO Importin subunit beta-3 OS=Schizos...1580.0002     49.3     23     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
12P38217    918   IMB2_YEAST Importin subunit beta-2 OS=Sacchar...1280.00006     50.4     23     48GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.
GO:0008139; F:nuclear localization sequence binding; IPI:SGD.
GO:0007049; P:cell cycle; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; IDA:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD.
13P42345    2549   MTOR_HUMAN Serine/threonine-protein kinase mT...3810.02     42.4     20     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB.
GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.
14Q91YE6    1041   IPO9_MOUSE Importin-9 OS=Mus musculus (Mouse)...1300.058     40.8     25     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; ISS:UniProtKB.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
15Q96P70    1041   IPO9_HUMAN Importin-9 OS=Homo sapiens (Human)...1300.059     40.8     25     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008565; F:protein transporter activity; IDA:UniProtKB.
GO:0006606; P:protein import into nucleus; NAS:UniProtKB.
16Q8VI75    1082   IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)...2910.19     39.3     19     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
17Q9ZPY7    972   XPO2_ARATH Exportin-2 OS=Arabidopsis thaliana...1300.26     38.9     29     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
18Q8TEX9    1081   IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)...2910.56     37.7     19     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
19P42346    2549   MTOR_RAT Serine/threonine-protein kinase mTOR...3890.68     37.4     20     37GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD.
20Q9JLN9    2549   MTOR_MOUSE Serine/threonine-protein kinase mT...3810.89     37     20     37GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB.
GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI.
21Q9SLX0    534   IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryz...590.9     37     34     49GO:0005634; C:nucleus; IEA:InterPro.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
22Q54WR2    2667   GCN1L_DICDI Translational activator gcn1 OS=D...4351     37     22     41
GO:0005488; F:binding; IEA:InterPro.
GO:0006448; P:regulation of translational elongation; ISS:dictyBase.
23O04294    531   IMA2_ARATH Importin subunit alpha-2 OS=Arabid...971.7     35.8     30     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006952; P:defense response; IMP:TAIR.::GO:0006606; P:protein import into nucleus; IEA:InterPro.
24Q86C65    2380   TOR_DICDI Target of rapamycin OS=Dictyosteliu...1022.2     35.8     27     40GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
25Q8BIV3    1105   RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc...4503     35.4     20     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
26P30154    601   2AAB_HUMAN Serine/threonine-protein phosphata...1184     34.7     24     45
GO:0005488; F:binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
27P32337    1089   IMB3_YEAST Importin subunit beta-3 OS=Sacchar...1924.5     34.7     25     45GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD.
GO:0006406; P:mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD.
28Q71VM4    526   IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryz...1144.8     34.3     25     40GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006606; P:protein import into nucleus; IEA:InterPro.
29Q7TNP2    601   2AAB_MOUSE Serine/threonine-protein phosphata...1184.9     34.3     24     45
GO:0005515; F:protein binding; IPI:IntAct.
30Q5DU56    1064   NLRC3_MOUSE Protein NLRC3 OS=Mus musculus (Mo...995.3     34.7     27     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042110; P:T cell activation; ISS:UniProtKB.
31Q4QQT4    601   2AAB_RAT Serine/threonine-protein phosphatase...1186.2     34.3     24     45
GO:0005488; F:binding; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 33 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::