Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR337C
Length:
817
Number of sequences:
5887
Description:
YLR337C VRP1 SGDID:S000004329, Chr XII from 805106-802653, Genome Release 64-1-1, reverse complement, Verified ORF, "Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P37370    817   VRP1_YEAST Verprolin OS=Saccharomyces cerevis...8170     1513     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0003779; F:actin binding; IPI:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0007015; P:actin filament organization; IPI:SGD.::GO:0007121; P:bipolar cellular bud site selection; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.
2P0C7L0    485   WIPF3_MOUSE WAS/WASL-interacting protein fami...780.000005     53.5     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
3Q9Z0G8    485   WIPF3_RAT WAS/WASL-interacting protein family...860.000006     53.1     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IMP:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
4Q9P6R1    309   VRP1_SCHPO Verprolin OS=Schizosaccharomyces p...430.082     39.7     42     60GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0035840; C:old growing cell tip; IDA:PomBase.
GO:0003779; F:actin binding; ISS:PomBase.
GO:0000147; P:actin cortical patch assembly; IGI:PomBase.::GO:0045010; P:actin nucleation; IGI:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0051127; P:positive regulation of actin nucleation; IDA:PomBase.
5Q1LUA6    3028   TRIO_DANRE Triple functional domain protein O...1830.0002     48.5     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
6Q8K1I7    493   WIPF1_MOUSE WAS/WASL-interacting protein fami...330.0007     46.6     67     76GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030048; P:actin filament-based movement; IDA:MGI.
7O75962    3097   TRIO_HUMAN Triple functional domain protein O...1742.2     35.8     28     38GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
8Q6IN36    487   WIPF1_RAT WAS/WASL-interacting protein family...330.0008     46.6     67     76GO:0005884; C:actin filament; IDA:RGD.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IMP:RGD.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:RGD.
9Q55DU1    90   ACTOB_DICDI Actobindin-B/C OS=Dictyostelium d...240.39     35.4     63     75
GO:0003779; F:actin binding; ISS:dictyBase.
10A6NGB9    483   WIPF3_HUMAN WAS/WASL-interacting protein fami...1190.004     43.9     32     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
11O15602    85   ACTO_ENTHI Actobindin homolog OS=Entamoeba hi...270.15     36.6     63     85
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
12Q8R1S4    759   MTSS1_MOUSE Metastasis suppressor protein 1 O...270.25     38.5     67     78GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005102; F:receptor binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030041; P:actin filament polymerization; IDA:MGI.::GO:0071498; P:cellular response to fluid shear stress; IDA:UniProtKB.::GO:2001013; P:epithelial cell proliferation involved in renal tubule morphogenesis; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0072102; P:glomerulus morphogenesis; IMP:UniProtKB.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:UniProtKB.::GO:0072160; P:nephron tubule epithelial cell differentiation; IMP:UniProtKB.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
13O43312    755   MTSS1_HUMAN Metastasis suppressor protein 1 O...270.26     38.5     67     78GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0030139; C:endocytic vesicle; TAS:UniProtKB.::GO:0001726; C:ruffle; NAS:UniProtKB.
GO:0003785; F:actin monomer binding; IDA:UniProtKB.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0071498; P:cellular response to fluid shear stress; ISS:UniProtKB.::GO:2001013; P:epithelial cell proliferation involved in renal tubule morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0072102; P:glomerulus morphogenesis; ISS:UniProtKB.::GO:0030035; P:microspike assembly; NAS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0072160; P:nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:UniProtKB.
14Q8TF74    440   WIPF2_HUMAN WAS/WASL-interacting protein fami...1540.36     37.7     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
15Q9QW30    2471   NOTC2_RAT Neurogenic locus notch homolog prot...1220.71     37.4     25     38GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; TAS:RGD.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0001709; P:cell fate determination; IDA:RGD.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0050793; P:regulation of developmental process; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16A6R7X5    1481   PAN1_AJECN Actin cytoskeleton-regulatory comp...330.76     37.4     55     64GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
17Q4WG58    1467   PAN1_ASPFU Actin cytoskeleton-regulatory comp...321.3     36.6     50     66GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
18B0YC95    1467   PAN1_ASPFC Actin cytoskeleton-regulatory comp...321.3     36.6     50     66GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
19Q71LX6    3302   XIRP2_RAT Xin actin-binding repeat-containing...1541.3     36.6     22     43GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
20Q10172    1794   PAN1_SCHPO Actin cytoskeleton-regulatory comp...393.5     35     46     62GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.
21P50795    520   VL2_HPV21 Minor capsid protein L2 OS=Human pa...1203.6     34.7     31     45GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
22Q07008    2531   NOTC1_RAT Neurogenic locus notch homolog prot...3084.5     34.7     20     34GO:0001669; C:acrosomal vesicle; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0048708; P:astrocyte differentiation; IDA:RGD.::GO:0021515; P:cell differentiation in spinal cord; IEP:RGD.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.::GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0045603; P:positive regulation of endothelial cell differentiation; IMP:RGD.::GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:RGD.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; ISS:UniProtKB.::GO:0007221; P:positive regulation of transcription of Notch receptor target; IMP:RGD.::GO:0031960; P:response to corticosteroid stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q6PEV3    440   WIPF2_MOUSE WAS/WASL-interacting protein fami...2156.7     33.9     28     35GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
24Q1DQC1    1485   PAN1_COCIM Actin cytoskeleton-regulatory comp...336.8     33.9     48     58GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
25A2AAJ9    8891   OBSCN_MOUSE Obscurin OS=Mus musculus (Mouse)....1839.9     33.5     27     37GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
26Q2UDY8    1473   PAN1_ASPOR Actin cytoskeleton-regulatory comp...328.7     33.9     50     63GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
27Q673G8    837   DACT2_DANRE Dapper homolog 2 OS=Danio rerio (...2039     33.5     27     35GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:ZFIN.
GO:0048332; P:mesoderm morphogenesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IMP:ZFIN.
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