Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR323C
Length:
259
Number of sequences:
5887
Description:
YLR323C CWC24 SGDID:S000004315, Chr XII from 778952-778173, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...443.7     32.7     27     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
422A6NGJ6    449   TRI64_HUMAN Tripartite motif-containing prote...433.7     32.3     30     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
423Q8WU17    664   RN139_HUMAN E3 ubiquitin-protein ligase RNF13...443.7     32.7     27     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0070613; P:regulation of protein processing; IDA:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
424Q5C8T6    493   TRIM5_GORGO Tripartite motif-containing prote...443.8     32.3     30     48GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
425A5WW08    637   CHFR_DANRE E3 ubiquitin-protein ligase CHFR O...563.8     32.7     29     50GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
426A6NI03    449   TR64B_HUMAN Putative tripartite motif-contain...433.8     32.3     30     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
427Q12933    501   TRAF2_HUMAN TNF receptor-associated factor 2 ...443.8     32.3     30     45GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.
GO:0005174; F:CD40 receptor binding; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; NAS:ProtInc.::GO:0046625; F:sphingolipid binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0043623; P:cellular protein complex assembly; ISS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070207; P:protein homotrimerization; IPI:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
428Q7Z4K8    759   TRI46_HUMAN Tripartite motif-containing prote...393.8     32.7     36     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
429Q9LQM3    384   C3H12_ARATH Zinc finger CCCH domain-containin...413.9     32.3     34     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
430Q7TNM2    759   TRI46_MOUSE Tripartite motif-containing prote...393.9     32.7     36     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
431O48772    453   C3H26_ARATH Zinc finger CCCH domain-containin...425.6     32     29     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:TAIR.::GO:0004518; F:nuclease activity; TAS:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
432Q8RXD6    878   BRE1A_ARATH E3 ubiquitin-protein ligase BRE1-...294.1     32.7     41     48GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0033523; P:histone H2B ubiquitination; IMP:TAIR.::GO:0010390; P:histone monoubiquitination; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0010162; P:seed dormancy process; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
433Q6GQL0    918   CBLBA_XENLA E3 ubiquitin-protein ligase CBL-B...524.1     32.7     31     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.
434A4IIN5    333   TISD_XENTR Zinc finger protein 36, C3H1 type-...294.1     32.3     28     69GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
435Q6AZZ1    485   TRI68_HUMAN E3 ubiquitin-protein ligase TRIM6...454.2     32.3     29     44GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
436Q91829    1045   RAG1_XENLA V(D)J recombination-activating pro...764.2     32.3     30     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
437Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...444.3     32.3     27     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
438Q07352    338   TISB_HUMAN Zinc finger protein 36, C3H1 type-...294.7     32     31     66GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010467; P:gene expression; TAS:Reactome.::GO:0043488; P:regulation of mRNA stability; IDA:MGI.
439Q9D0C1    305   RN115_MOUSE E3 ubiquitin-protein ligase RNF11...714.3     32     31     45GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
440Q0JP11    167   C3H3_ORYSJ Zinc finger CCCH domain-containing...214.4     31.6     48     76
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
441Q554L2    831   Y4613_DICDI Probable inactive serine/threonin...854.5     32.3     32     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
442Q5NCC9    485   TRI58_MOUSE Tripartite motif-containing prote...284.6     32.3     32     64GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
443Q94AD9    404   C3H3_ARATH Zinc finger CCCH domain-containing...277.4     31.6     48     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
444P15919    1040   RAG1_MOUSE V(D)J recombination-activating pro...394.7     32.3     36     51GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004519; F:endonuclease activity; IMP:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:MGI.::GO:0070244; P:negative regulation of thymocyte apoptotic process; IMP:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; IMP:UniProtKB.::GO:0033151; P:V(D)J recombination; IMP:UniProtKB.
445Q9BZY9    425   TRI31_HUMAN E3 ubiquitin-protein ligase TRIM3...384.7     32.3     32     47GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
446Q9DD48    423   MKRN2_SERQU Probable E3 ubiquitin-protein lig...1104.7     32     24     41
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
447Q9FKD5    276   SINL9_ARATH Putative E3 ubiquitin-protein lig...594.8     32     37     47GO:0005634; C:nucleus; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
448P14373    513   TRI27_HUMAN Zinc finger protein RFP OS=Homo s...274.9     32.3     33     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0031965; C:nuclear membrane; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.::GO:0002820; P:negative regulation of adaptive immune response; IMP:UniProtKB.::GO:0090281; P:negative regulation of calcium ion import; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:MGI.::GO:1900041; P:negative regulation of interleukin-2 secretion; IMP:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
449B3DK16    234   PCF5A_DANRE Polycomb group RING finger protei...445.1     31.6     32     50GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
450P34088    1042   RAG1_RABIT V(D)J recombination-activating pro...415.1     32.3     34     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
451Q8GXX7    397   C3H33_ARATH Zinc finger CCCH domain-containin...605.6     32     30     45GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:TAIR.::GO:0048027; F:mRNA 5'-UTR binding; IPI:TAIR.::GO:0004518; F:nuclease activity; TAS:TAIR.::GO:0010313; F:phytochrome binding; IPI:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0017148; P:negative regulation of translation; IMP:TAIR.
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