Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR323C
Length:
259
Number of sequences:
5887
Description:
YLR323C CWC24 SGDID:S000004315, Chr XII from 778952-778173, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...402.4     33.1     30     50GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
392Q6PC78    194   RN185_DANRE E3 ubiquitin-protein ligase RNF18...272.4     32.3     41     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
393Q9HBD1    1191   RC3H2_HUMAN RING finger and CCCH-type zinc fi...422.5     33.1     31     60GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
394Q9BUZ4    470   TRAF4_HUMAN TNF receptor-associated factor 4 ...342.5     33.1     38     59GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0090073; P:positive regulation of protein homodimerization activity; IDA:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; TAS:ProtInc.
395Q5XIK5    352   RN146_RAT E3 ubiquitin-protein ligase RNF146 ...422.5     32.7     31     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
396Q7TPK1    774   UHRF1_RAT E3 ubiquitin-protein ligase UHRF1 O...632.5     33.1     30     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
397Q9CZW6    359   RN146_MOUSE E3 ubiquitin-protein ligase RNF14...422.6     32.7     31     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
398Q99942    180   RNF5_HUMAN E3 ubiquitin-protein ligase RNF5 O...262.6     32.3     42     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
399Q5D7I3    495   TRIM5_ERYPA Tripartite motif-containing prote...312.6     33.1     39     52GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
400Q61382    470   TRAF4_MOUSE TNF receptor-associated factor 4 ...342.7     33.1     38     59GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007585; P:respiratory gaseous exchange; IMP:MGI.::GO:0030323; P:respiratory tube development; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
401Q5FWH2    727   UNKL_MOUSE Putative E3 ubiquitin-protein liga...312.7     33.1     42     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
402Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...402.7     33.1     30     50GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
403Q7ZYZ7    261   PCGF1_DANRE Polycomb group RING finger protei...782.8     32.7     26     46GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
404Q60803    567   TRAF3_MOUSE TNF receptor-associated factor 3 ...432.8     33.1     37     51GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0050688; P:regulation of defense response to virus; IMP:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
405Q5T8P6    1007   RBM26_HUMAN RNA-binding protein 26 OS=Homo sa...232.9     33.1     48     61
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
406Q6NZN0    1012   RBM26_MOUSE RNA-binding protein 26 OS=Mus mus...233     33.1     48     61
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
407P15533    496   TR30A_MOUSE Tripartite motif-containing prote...353     32.7     37     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032715; P:negative regulation of interleukin-6 production; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
408Q5D7I0    494   TRIM5_SAISC Tripartite motif-containing prote...323.1     32.7     34     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
409Q2T9I5    1059   RBM26_XENLA RNA-binding protein 26 OS=Xenopus...233.1     33.1     48     61
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
410Q5BN31    494   TRIM5_SAIBB Tripartite motif-containing prote...323.2     32.7     34     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
411Q5F3B2    244   RN166_CHICK RING finger protein 166 OS=Gallus...673.2     32.3     31     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
412Q9QXP6    481   MKRN1_MOUSE E3 ubiquitin-protein ligase makor...233.2     32.7     61     74
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
413Q1ZXR0    502   Y8444_DICDI TNF receptor-associated factor fa...493.3     32.7     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
414P17431    338   TISB_RAT Zinc finger protein 36, C3H1 type-li...295     32     31     66GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017091; F:AU-rich element binding; IMP:RGD.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
415P23950    338   TISB_MOUSE Zinc finger protein 36, C3H1 type-...294.9     32     31     66GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:MGI.::GO:0006417; P:regulation of translation; IMP:MGI.::GO:0033077; P:T cell differentiation in thymus; IGI:BHF-UCL.::GO:0001570; P:vasculogenesis; IMP:MGI.
416Q9UHC7    482   MKRN1_HUMAN E3 ubiquitin-protein ligase makor...233.3     32.7     61     74
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
417Q5RBG2    492   TRI35_PONAB Tripartite motif-containing prote...403.3     32.7     28     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
418Q6NRE7    764   CBLBB_XENLA E3 ubiquitin-protein ligase CBL-B...523.4     32.7     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.
419Q9UPQ4    493   TRI35_HUMAN Tripartite motif-containing prote...403.4     32.7     28     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
420A6NLI5    447   TR64C_HUMAN Putative tripartite motif-contain...433.6     32.7     30     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
421Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...443.7     32.7     27     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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