rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q9R1A8 | 733 | RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2... | 40 | 2.4 | 33.1 | 30 | 50 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 392 | Q6PC78 | 194 | RN185_DANRE E3 ubiquitin-protein ligase RNF18... | 27 | 2.4 | 32.3 | 41 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 393 | Q9HBD1 | 1191 | RC3H2_HUMAN RING finger and CCCH-type zinc fi... | 42 | 2.5 | 33.1 | 31 | 60 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 394 | Q9BUZ4 | 470 | TRAF4_HUMAN TNF receptor-associated factor 4 ... | 34 | 2.5 | 33.1 | 38 | 59 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0090073; P:positive regulation of protein homodimerization activity; IDA:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; TAS:ProtInc. | 395 | Q5XIK5 | 352 | RN146_RAT E3 ubiquitin-protein ligase RNF146 ... | 42 | 2.5 | 32.7 | 31 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 396 | Q7TPK1 | 774 | UHRF1_RAT E3 ubiquitin-protein ligase UHRF1 O... | 63 | 2.5 | 33.1 | 30 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 397 | Q9CZW6 | 359 | RN146_MOUSE E3 ubiquitin-protein ligase RNF14... | 42 | 2.6 | 32.7 | 31 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 398 | Q99942 | 180 | RNF5_HUMAN E3 ubiquitin-protein ligase RNF5 O... | 26 | 2.6 | 32.3 | 42 | 62 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB. | 399 | Q5D7I3 | 495 | TRIM5_ERYPA Tripartite motif-containing prote... | 31 | 2.6 | 33.1 | 39 | 52 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 400 | Q61382 | 470 | TRAF4_MOUSE TNF receptor-associated factor 4 ... | 34 | 2.7 | 33.1 | 38 | 59 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007585; P:respiratory gaseous exchange; IMP:MGI.::GO:0030323; P:respiratory tube development; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 401 | Q5FWH2 | 727 | UNKL_MOUSE Putative E3 ubiquitin-protein liga... | 31 | 2.7 | 33.1 | 42 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 402 | Q8NHY2 | 731 | RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2... | 40 | 2.7 | 33.1 | 30 | 50 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome. | 403 | Q7ZYZ7 | 261 | PCGF1_DANRE Polycomb group RING finger protei... | 78 | 2.8 | 32.7 | 26 | 46 | GO:0031519; C:PcG protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 404 | Q60803 | 567 | TRAF3_MOUSE TNF receptor-associated factor 3 ... | 43 | 2.8 | 33.1 | 37 | 51 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0050688; P:regulation of defense response to virus; IMP:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB. | 405 | Q5T8P6 | 1007 | RBM26_HUMAN RNA-binding protein 26 OS=Homo sa... | 23 | 2.9 | 33.1 | 48 | 61 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 406 | Q6NZN0 | 1012 | RBM26_MOUSE RNA-binding protein 26 OS=Mus mus... | 23 | 3 | 33.1 | 48 | 61 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 407 | P15533 | 496 | TR30A_MOUSE Tripartite motif-containing prote... | 35 | 3 | 32.7 | 37 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032715; P:negative regulation of interleukin-6 production; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 408 | Q5D7I0 | 494 | TRIM5_SAISC Tripartite motif-containing prote... | 32 | 3.1 | 32.7 | 34 | 53 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 409 | Q2T9I5 | 1059 | RBM26_XENLA RNA-binding protein 26 OS=Xenopus... | 23 | 3.1 | 33.1 | 48 | 61 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 410 | Q5BN31 | 494 | TRIM5_SAIBB Tripartite motif-containing prote... | 32 | 3.2 | 32.7 | 34 | 53 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 411 | Q5F3B2 | 244 | RN166_CHICK RING finger protein 166 OS=Gallus... | 67 | 3.2 | 32.3 | 31 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 412 | Q9QXP6 | 481 | MKRN1_MOUSE E3 ubiquitin-protein ligase makor... | 23 | 3.2 | 32.7 | 61 | 74 | | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 413 | Q1ZXR0 | 502 | Y8444_DICDI TNF receptor-associated factor fa... | 49 | 3.3 | 32.7 | 31 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. | 414 | P17431 | 338 | TISB_RAT Zinc finger protein 36, C3H1 type-li... | 29 | 5 | 32 | 31 | 66 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017091; F:AU-rich element binding; IMP:RGD.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 415 | P23950 | 338 | TISB_MOUSE Zinc finger protein 36, C3H1 type-... | 29 | 4.9 | 32 | 31 | 66 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:MGI.::GO:0006417; P:regulation of translation; IMP:MGI.::GO:0033077; P:T cell differentiation in thymus; IGI:BHF-UCL.::GO:0001570; P:vasculogenesis; IMP:MGI. | 416 | Q9UHC7 | 482 | MKRN1_HUMAN E3 ubiquitin-protein ligase makor... | 23 | 3.3 | 32.7 | 61 | 74 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 417 | Q5RBG2 | 492 | TRI35_PONAB Tripartite motif-containing prote... | 40 | 3.3 | 32.7 | 28 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 418 | Q6NRE7 | 764 | CBLBB_XENLA E3 ubiquitin-protein ligase CBL-B... | 52 | 3.4 | 32.7 | 31 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro. | 419 | Q9UPQ4 | 493 | TRI35_HUMAN Tripartite motif-containing prote... | 40 | 3.4 | 32.7 | 28 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB. | 420 | A6NLI5 | 447 | TR64C_HUMAN Putative tripartite motif-contain... | 43 | 3.6 | 32.7 | 30 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 421 | Q5RBT7 | 664 | RN139_PONAB E3 ubiquitin-protein ligase RNF13... | 44 | 3.7 | 32.7 | 27 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |