Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR323C
Length:
259
Number of sequences:
5887
Description:
YLR323C CWC24 SGDID:S000004315, Chr XII from 778952-778173, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q3MV19    556   TRF6A_XENLA TNF receptor-associated factor 6-...400.77     34.7     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
272Q80XJ2    565   RN168_MOUSE E3 ubiquitin-protein ligase RNF16...360.81     34.7     33     44GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
273Q28DL4    558   TRAF6_XENTR TNF receptor-associated factor 6 ...400.82     34.7     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
274Q9DCN7    395   RNFT1_MOUSE RING finger and transmembrane dom...380.83     34.7     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
275O88846    194   RNF4_RAT E3 ubiquitin-protein ligase RNF4 OS=...490.84     33.9     31     39GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:RGD.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:RGD.::GO:0031491; F:nucleosome binding; IDA:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:RGD.::GO:0032184; F:SUMO polymer binding; IPI:UniProtKB.::GO:0017025; F:TBP-class protein binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
276Q9QZS2    194   RNF4_MOUSE E3 ubiquitin-protein ligase RNF4 O...490.84     33.9     31     39GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
277B6CJY4    522   TRAF6_CERAT TNF receptor-associated factor 6 ...400.84     34.7     35     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
278Q920M2    352   RNF39_RAT RING finger protein 39 OS=Rattus no...270.85     34.3     44     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048168; P:regulation of neuronal synaptic plasticity; NAS:RGD.
279Q9Y4K3    522   TRAF6_HUMAN TNF receptor-associated factor 6 ...400.85     34.7     35     55GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
280B6CJY5    522   TRAF6_MACMU TNF receptor-associated factor 6 ...400.86     34.7     35     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
281B2RYR0    564   RN168_RAT E3 ubiquitin-protein ligase RNF168 ...360.89     34.7     33     44GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
282P15918    1043   RAG1_HUMAN V(D)J recombination-activating pro...390.89     34.7     38     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
283Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...270.92     34.3     41     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
284P43254    675   COP1_ARATH E3 ubiquitin-protein ligase COP1 O...380.93     34.7     32     47GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000152; C:nuclear ubiquitin ligase complex; TAS:TAIR.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046283; P:anthocyanin metabolic process; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0009649; P:entrainment of circadian clock; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IGI:TAIR.::GO:0048573; P:photoperiodism, flowering; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009641; P:shade avoidance; IMP:TAIR.::GO:0009647; P:skotomorphogenesis; TAS:TAIR.
285Q5C8U1    494   TRIM5_SAGLB Tripartite motif-containing prote...330.93     34.3     36     55GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
286Q5D7I6    551   TRIM5_ALOSA Tripartite motif-containing prote...460.93     34.3     30     48GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
287Q54S31    374   PEX10_DICDI Peroxisome biogenesis factor 10 O...390.93     34.3     38     46GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
288Q6L5G1    343   C3H39_ORYSJ Zinc finger CCCH domain-containin...320.93     34.3     34     63
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
289Q1ACD5    494   TRIM5_SAGOE Tripartite motif-containing prote...330.96     34.3     36     55GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
290Q5D7H8    494   TRIM5_CALDO Tripartite motif-containing prote...330.96     34.3     36     55GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
291Q9BVG3    475   TRI62_HUMAN Tripartite motif-containing prote...270.96     34.3     41     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
292Q7YR33    465   TRI15_PANTR Tripartite motif-containing prote...570.98     34.3     28     39GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
293Q5ACX1    1084   RAD5_CANAL DNA repair protein RAD5 OS=Candida...440.99     34.7     41     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
294Q86UV6    250   TRI74_HUMAN Tripartite motif-containing prote...531     33.9     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
295Q5NAV3    466   C3H5_ORYSJ Zinc finger CCCH domain-containing...231     34.3     52     74GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
296Q28GL3    416   RNFT1_XENTR RING finger and transmembrane dom...381     34.3     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
297Q86UV7    250   TRI73_HUMAN Tripartite motif-containing prote...531     33.9     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
298Q5D7I5    494   TRIM5_CEBPY Tripartite motif-containing prote...331     34.3     36     55GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
299Q8IYW5    571   RN168_HUMAN E3 ubiquitin-protein ligase RNF16...361.1     34.3     33     47GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
300Q09463    235   RNF5_CAEEL RING finger protein 5 OS=Caenorhab...541.1     33.9     30     46GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase.
301Q13191    982   CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B ...521.1     34.3     33     42
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