Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR323C
Length:
259
Number of sequences:
5887
Description:
YLR323C CWC24 SGDID:S000004315, Chr XII from 778952-778173, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q8L829    552   ARI5_ARATH Probable E3 ubiquitin-protein liga...610.47     35.4     34     49
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
242Q96F44    468   TRI11_HUMAN E3 ubiquitin-protein ligase TRIM1...380.47     35.4     32     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
243Q12899    539   TRI26_HUMAN Tripartite motif-containing prote...240.48     35.4     46     67
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
244P62603    542   TRI26_RAT Tripartite motif-containing protein...240.48     35.4     46     67GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
245B1H278    467   TRI11_RAT E3 ubiquitin-protein ligase TRIM11 ...470.48     35.4     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
246Q681I0    465   ORTHL_ARATH E3 ubiquitin-protein ligase ORTHR...410.49     35.4     39     51GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; ISS:UniProtKB.
247Q7TPM3    477   TRI17_MOUSE E3 ubiquitin-protein ligase TRIM1...250.5     35     44     64GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
248P22682    913   CBL_MOUSE E3 ubiquitin-protein ligase CBL OS=...520.51     35.4     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
249Q1ACD6    494   TRIM5_HYLSY Tripartite motif-containing prote...660.51     35     27     44GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
250E7FAP1    630   RN169_DANRE E3 ubiquitin-protein ligase RNF16...470.51     35.4     34     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
251Q1ACD7    494   TRIM5_NOMLE Tripartite motif-containing prote...660.52     35     27     44GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
252Q99PN3    545   TRI26_MOUSE Tripartite motif-containing prote...240.53     35     46     67GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
253P22681    906   CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=...520.53     35.4     31     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC.
254Q94131    335   PIE1_CAEEL Pharynx and intestine in excess pr...410.53     35     24     56GO:0005813; C:centrosome; IDA:WormBase.::GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0043186; C:P granule; IDA:WormBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0001704; P:formation of primary germ layer; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
255Q9WV59    477   TRI17_RAT E3 ubiquitin-protein ligase TRIM17 ...250.54     35     44     64GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
256Q99PQ2    467   TRI11_MOUSE E3 ubiquitin-protein ligase TRIM1...380.55     35     32     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050768; P:negative regulation of neurogenesis; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
257A3BUD2    605   C3H57_ORYSJ Putative zinc finger CCCH domain-...280.55     35     39     71
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
258Q5ZDJ6    462   C3H8_ORYSJ Zinc finger CCCH domain-containing...540.58     35     33     50
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
259A6NDI0    452   TR49B_HUMAN Putative tripartite motif-contain...450.58     35     38     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
260P40072    274   SLX8_YEAST E3 ubiquitin-protein ligase comple...370.61     34.7     30     54GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD.
261Q6R567    252   RMA1_CAPAN E3 ubiquitin-protein ligase RMA1H1...290.64     34.7     41     55GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009723; P:response to ethylene stimulus; IEP:UniProtKB.::GO:0006970; P:response to osmotic stress; IEP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.
262Q3ZCC3    542   TRAF6_BOVIN TNF receptor-associated factor 6 ...400.65     35     35     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
263Q2YEM8    494   TRIM5_BUNHO Tripartite motif-containing prote...660.65     35     27     44GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
264Q3UWA4    246   TRI40_MOUSE Tripartite motif-containing prote...450.66     34.7     33     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
265P70196    530   TRAF6_MOUSE TNF receptor-associated factor 6 ...400.66     35     35     55GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0004871; F:signal transducer activity; TAS:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.::GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0048468; P:cell development; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IMP:MGI.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0051023; P:regulation of immunoglobulin secretion; IDA:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI.
266B5DF45    530   TRAF6_RAT TNF receptor-associated factor 6 OS...400.69     34.7     35     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
267A7XUJ6    541   TRAF6_PIG TNF receptor-associated factor 6 OS...400.74     34.7     35     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
268Q86KL1    1080   BRE1_DICDI Probable E3 ubiquitin-protein liga...430.74     35     28     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
269P78317    190   RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 O...490.75     33.9     31     39GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.::GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
270A2ZVY5    333   C3H9_ORYSJ Zinc finger CCCH domain-containing...310.77     34.7     35     65
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
271Q3MV19    556   TRF6A_XENLA TNF receptor-associated factor 6-...400.77     34.7     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
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