Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR318W
Length:
884
Number of sequences:
5887
Description:
YLR318W EST2 SGDID:S000004310, Chr XII from 766542-769196, Genome Release 64-1-1, Verified ORF, "Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06163    884   TERT_YEAST Telomerase reverse transcriptase O...8840     1813     100     100GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0000333; C:telomerase catalytic core complex; IPI:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0042162; F:telomeric DNA binding; IDA:SGD.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; TAS:SGD.
GO:0001302; P:replicative cell aging; IGI:SGD.::GO:0007004; P:telomere maintenance via telomerase; IDA:SGD.
2O13339    988   TERT_SCHPO Telomerase reverse transcriptase O...5043e-29     129     25     47GO:0000781; C:chromosome, telomeric region; IC:PomBase.::GO:0000228; C:nuclear chromosome; IC:PomBase.::GO:0000333; C:telomerase catalytic core complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IPI:PomBase.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IMP:PomBase.
GO:0007004; P:telomere maintenance via telomerase; IMP:PomBase.
3O14746    1132   TERT_HUMAN Telomerase reverse transcriptase O...7149e-25     115     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000783; C:nuclear telomere cap complex; IC:BHF-UCL.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005697; C:telomerase holoenzyme complex; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0042162; F:telomeric DNA binding; TAS:ProtInc.::GO:0070034; F:telomeric RNA binding; IDA:BHF-UCL.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; TAS:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0022616; P:DNA strand elongation; IDA:BHF-UCL.::GO:0090399; P:replicative senescence; IMP:BHF-UCL.::GO:0032203; P:telomere formation via telomerase; IDA:BHF-UCL.::GO:0007004; P:telomere maintenance via telomerase; IMP:BHF-UCL.
4Q27ID4    1125   TERT_BOVIN Telomerase reverse transcriptase O...6236e-24     112     21     40GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
5Q6A548    1123   TERT_CANFA Telomerase reverse transcriptase O...7231e-22     108     22     41GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
6Q673L6    1125   TERT_RAT Telomerase reverse transcriptase OS=...6278e-19     95.9     22     41GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; TAS:RGD.
7O70372    1122   TERT_MOUSE Telomerase reverse transcriptase O...6172e-17     90.9     22     41GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
8Q8LKW0    1259   TERT_ORYSJ Telomerase reverse transcriptase O...6810.00000000000008     79.7     20     40GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
9O76332    1132   TERT_OXYTR Telomerase reverse transcriptase O...8140.0000000000008     76.3     21     39GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
10Q9SPU7    1123   TERT_ARATH Telomerase reverse transcriptase O...4960.00000000008     69.7     22     40GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0050000; P:chromosome localization; IMP:TAIR.::GO:0007000; P:nucleolus organization; IMP:TAIR.::GO:0007004; P:telomere maintenance via telomerase; IMP:TAIR.
11O00939    1031   TERT_EUPAE Telomerase reverse transcriptase O...3830.0000002     58.9     22     44GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
12O77448    1117   TERT_TETTH Telomerase reverse transcriptase O...2060.004     45.1     21     45GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
13P19593    608   RDPO_SCEOB Probable reverse transcriptase OS=...1312.7     35.4     27     43GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
14B2IC04    85   Y1628_BEII9 UPF0386 protein Bind_1628 OS=8712...544.7     32     33     61
records
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