rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P37032 | 891 | ACON_LEGPH Aconitate hydratase OS=ATCC 33152 ... | 831 | 4e-57 | 213 | 29 | 42 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 32 | Q63270 | 889 | ACOC_RAT Cytoplasmic aconitate hydratase OS=R... | 815 | 3e-56 | 211 | 30 | 43 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005792; C:microsome; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048027; F:mRNA 5'-UTR binding; IDA:RGD. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IDA:RGD.::GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0006417; P:regulation of translation; TAS:RGD.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 33 | Q8CPC2 | 901 | ACON_STAES Aconitate hydratase OS=Staphylococ... | 826 | 8e-56 | 209 | 27 | 43 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 34 | Q5HPJ0 | 901 | ACON_STAEQ Aconitate hydratase OS=Staphylococ... | 826 | 8e-56 | 209 | 27 | 43 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 35 | Q8FTA8 | 937 | ACON_COREF Aconitate hydratase OS=11189 / NBR... | 864 | 2e-55 | 209 | 27 | 42 | | | | | | | | | | | GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 36 | Q90875 | 889 | ACOC_CHICK Cytoplasmic aconitate hydratase OS... | 814 | 8e-55 | 206 | 29 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 37 | Q42669 | 764 | ACOC_CUCMC Aconitate hydratase OS=Cucumis mel... | 768 | 1e-54 | 205 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW. | 38 | Q2A1K3 | 937 | ACON_FRATH Aconitate hydratase OS=Francisella... | 815 | 3e-54 | 205 | 28 | 43 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 39 | Q54X73 | 894 | ACOC_DICDI Probable cytoplasmic aconitate hyd... | 759 | 5e-54 | 204 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 40 | Q23500 | 887 | ACOC_CAEEL Probable cytoplasmic aconitate hyd... | 824 | 6e-54 | 204 | 27 | 42 | GO:0005829; C:cytosol; IDA:WormBase. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 41 | Q62751 | 963 | IREB2_RAT Iron-responsive element-binding pro... | 830 | 1e-53 | 204 | 27 | 43 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.::GO:0030350; F:iron-responsive element binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 42 | Q811J3 | 963 | IREB2_MOUSE Iron-responsive element-binding p... | 826 | 6e-53 | 201 | 27 | 42 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030371; F:translation repressor activity; TAS:MGI. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IDA:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0050892; P:intestinal absorption; IGI:MGI.::GO:0030316; P:osteoclast differentiation; IEP:DFLAT.::GO:0009791; P:post-embryonic development; IGI:MGI.::GO:0006782; P:protoporphyrinogen IX biosynthetic process; IMP:MGI. | 43 | B3VKQ2 | 964 | IREB2_PIG Iron-responsive element-binding pro... | 835 | 1e-52 | 201 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008152; P:metabolic process; IEA:InterPro. | 44 | Q8NQ98 | 939 | ACON_CORGL Aconitate hydratase OS=LMG 3730 / ... | 861 | 2e-52 | 200 | 27 | 42 | | | | | | | | | | | GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 45 | Q59938 | 888 | ACON_STRMU Aconitate hydratase OS=Streptococc... | 759 | 2e-52 | 199 | 29 | 43 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 46 | Q6GH55 | 901 | ACON_STAAR Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 47 | P63434 | 901 | ACON_STAAW Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 48 | Q6G9K9 | 901 | ACON_STAAS Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 49 | P99148 | 901 | ACON_STAAN Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 50 | P63433 | 901 | ACON_STAAM Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 51 | Q5HG69 | 901 | ACON_STAAC Aconitate hydratase OS=Staphylococ... | 782 | 1e-51 | 197 | 27 | 41 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 52 | Q97EE0 | 422 | LEUC_CLOAB 3-isopropylmalate dehydratase larg... | 438 | 1e-51 | 190 | 33 | 49 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 53 | P48200 | 963 | IREB2_HUMAN Iron-responsive element-binding p... | 825 | 2e-51 | 197 | 26 | 42 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006826; P:iron ion transport; TAS:UniProtKB. | 54 | P25516 | 891 | ACON1_ECOLI Aconitate hydratase 1 OS=Escheric... | 801 | 3e-50 | 193 | 27 | 42 | GO:0005737; C:cytoplasm; IDA:EcoliWiki. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:EcoCyc.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0005506; F:iron ion binding; IMP:EcoliWiki.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0003730; F:mRNA 3'-UTR binding; IDA:EcoCyc. | | | | | | | | | | GO:0009061; P:anaerobic respiration; IDA:EcoliWiki.::GO:0043556; P:regulation of translation in response to oxidative stress; IDA:EcoliWiki.::GO:0006099; P:tricarboxylic acid cycle; IDA:EcoliWiki. | 55 | Q9I3F5 | 910 | ACON1_PSEAE Aconitate hydratase 1 OS=12228). ... | 838 | 4e-50 | 192 | 28 | 42 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 56 | O28084 | 416 | LEUC2_ARCFU 3-isopropylmalate dehydratase lar... | 434 | 1e-49 | 184 | 32 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 57 | Q9WYC7 | 418 | LEUC1_THEMA 3-isopropylmalate dehydratase lar... | 443 | 1e-49 | 184 | 31 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 58 | B4U7U5 | 424 | LEUC_HYDS0 3-isopropylmalate dehydratase larg... | 417 | 5e-49 | 182 | 32 | 48 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 59 | B2KBD7 | 418 | LEUC_ELUMP 3-isopropylmalate dehydratase larg... | 446 | 5e-49 | 182 | 30 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 60 | O28316 | 418 | LEUC1_ARCFU 3-isopropylmalate dehydratase lar... | 337 | 3e-47 | 177 | 34 | 52 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 61 | Q2HZ33 | 688 | LYS4_CANPA Homoaconitase, mitochondrial OS=Ca... | 652 | 4e-47 | 182 | 28 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. |