Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR304C
Length:
778
Number of sequences:
5887
Description:
YLR304C ACO1 SGDID:S000004295, Chr XII from 737548-735212, Genome Release 64-1-1, reverse complement, Verified ORF, "Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P37032    891   ACON_LEGPH Aconitate hydratase OS=ATCC 33152 ...8314e-57     213     29     42
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
32Q63270    889   ACOC_RAT Cytoplasmic aconitate hydratase OS=R...8153e-56     211     30     43GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005792; C:microsome; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048027; F:mRNA 5'-UTR binding; IDA:RGD.
GO:0006879; P:cellular iron ion homeostasis; IDA:RGD.::GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0006417; P:regulation of translation; TAS:RGD.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
33Q8CPC2    901   ACON_STAES Aconitate hydratase OS=Staphylococ...8268e-56     209     27     43
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
34Q5HPJ0    901   ACON_STAEQ Aconitate hydratase OS=Staphylococ...8268e-56     209     27     43
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
35Q8FTA8    937   ACON_COREF Aconitate hydratase OS=11189 / NBR...8642e-55     209     27     42
GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
36Q90875    889   ACOC_CHICK Cytoplasmic aconitate hydratase OS...8148e-55     206     29     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
37Q42669    764   ACOC_CUCMC Aconitate hydratase OS=Cucumis mel...7681e-54     205     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
38Q2A1K3    937   ACON_FRATH Aconitate hydratase OS=Francisella...8153e-54     205     28     43
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
39Q54X73    894   ACOC_DICDI Probable cytoplasmic aconitate hyd...7595e-54     204     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
40Q23500    887   ACOC_CAEEL Probable cytoplasmic aconitate hyd...8246e-54     204     27     42GO:0005829; C:cytosol; IDA:WormBase.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
41Q62751    963   IREB2_RAT Iron-responsive element-binding pro...8301e-53     204     27     43
GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.::GO:0030350; F:iron-responsive element binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
42Q811J3    963   IREB2_MOUSE Iron-responsive element-binding p...8266e-53     201     27     42GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030371; F:translation repressor activity; TAS:MGI.
GO:0006879; P:cellular iron ion homeostasis; IDA:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0050892; P:intestinal absorption; IGI:MGI.::GO:0030316; P:osteoclast differentiation; IEP:DFLAT.::GO:0009791; P:post-embryonic development; IGI:MGI.::GO:0006782; P:protoporphyrinogen IX biosynthetic process; IMP:MGI.
43B3VKQ2    964   IREB2_PIG Iron-responsive element-binding pro...8351e-52     201     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008152; P:metabolic process; IEA:InterPro.
44Q8NQ98    939   ACON_CORGL Aconitate hydratase OS=LMG 3730 / ...8612e-52     200     27     42
GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
45Q59938    888   ACON_STRMU Aconitate hydratase OS=Streptococc...7592e-52     199     29     43
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
46Q6GH55    901   ACON_STAAR Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
47P63434    901   ACON_STAAW Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
48Q6G9K9    901   ACON_STAAS Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
49P99148    901   ACON_STAAN Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
50P63433    901   ACON_STAAM Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
51Q5HG69    901   ACON_STAAC Aconitate hydratase OS=Staphylococ...7821e-51     197     27     41
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
52Q97EE0    422   LEUC_CLOAB 3-isopropylmalate dehydratase larg...4381e-51     190     33     49
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
53P48200    963   IREB2_HUMAN Iron-responsive element-binding p...8252e-51     197     26     42
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006826; P:iron ion transport; TAS:UniProtKB.
54P25516    891   ACON1_ECOLI Aconitate hydratase 1 OS=Escheric...8013e-50     193     27     42GO:0005737; C:cytoplasm; IDA:EcoliWiki.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:EcoCyc.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0005506; F:iron ion binding; IMP:EcoliWiki.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0003730; F:mRNA 3'-UTR binding; IDA:EcoCyc.
GO:0009061; P:anaerobic respiration; IDA:EcoliWiki.::GO:0043556; P:regulation of translation in response to oxidative stress; IDA:EcoliWiki.::GO:0006099; P:tricarboxylic acid cycle; IDA:EcoliWiki.
55Q9I3F5    910   ACON1_PSEAE Aconitate hydratase 1 OS=12228). ...8384e-50     192     28     42
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
56O28084    416   LEUC2_ARCFU 3-isopropylmalate dehydratase lar...4341e-49     184     32     47
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
57Q9WYC7    418   LEUC1_THEMA 3-isopropylmalate dehydratase lar...4431e-49     184     31     47
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
58B4U7U5    424   LEUC_HYDS0 3-isopropylmalate dehydratase larg...4175e-49     182     32     48
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
59B2KBD7    418   LEUC_ELUMP 3-isopropylmalate dehydratase larg...4465e-49     182     30     47
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
60O28316    418   LEUC1_ARCFU 3-isopropylmalate dehydratase lar...3373e-47     177     34     52
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
61Q2HZ33    688   LYS4_CANPA Homoaconitase, mitochondrial OS=Ca...6524e-47     182     28     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
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