Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR247C
Length:
1556
Number of sequences:
5887
Description:
YLR247C IRC20 SGDID:S000004237, Chr XII from 633354-628684, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661B5DF45    530   TRAF6_RAT TNF receptor-associated factor 6 OS...380.53     38.5     45     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
662P35820    1601   PSC_DROME Polycomb group protein Psc OS=Droso...390.53     38.9     38     54GO:0005725; C:intercalary heterochromatin; NAS:FlyBase.::GO:0005704; C:polytene chromosome band; IDA:FlyBase.::GO:0035102; C:PRC1 complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006338; P:chromatin remodeling; IDA:FlyBase.::GO:0006342; P:chromatin silencing; IDA:FlyBase.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.
663Q922Y2    403   TRI59_MOUSE Tripartite motif-containing prote...820.53     38.1     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
664Q55DU4    333   NOSIP_DICDI Nitric oxide synthase-interacting...610.53     38.1     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050999; P:regulation of nitric-oxide synthase activity; ISS:dictyBase.
665Q7SDY3    405   CWC24_NEUCR Pre-mRNA-splicing factor cwc-24 O...440.55     38.1     36     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
666P19474    475   RO52_HUMAN E3 ubiquitin-protein ligase TRIM21...840.56     38.5     31     42GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.
667Q803I8    625   SYVN1_DANRE E3 ubiquitin-protein ligase synov...400.56     38.5     38     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
668Q7ZWM8    343   RNG2B_XENLA E3 ubiquitin-protein ligase RING2...430.56     38.1     44     58GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
669Q1JPS1    232   PCF5B_DANRE Polycomb group RING finger protei...440.57     37.7     34     55GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
670Q03601    974   NHL1_CAEEL RING finger protein nhl-1 OS=Caeno...610.57     38.5     33     49
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.
671Q9SUS5    157   RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B...580.58     36.6     34     52
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
672P05470    597   YKP4_KLULA Uncharacterized killer plasmid pGK...1630.59     38.5     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
673Q94BY6    226   ATL75_ARATH RING-H2 finger protein ATL75 OS=A...430.6     37.4     40     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
674Q8RXD3    310   AIP2_ARATH E3 ubiquitin-protein ligase AIP2 O...420.6     37.7     38     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB.
675Q9SUS4    159   RHA1A_ARATH RING-H2 zinc finger protein RHA1a...450.65     36.6     33     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
676Q8BI21    518   RNF38_MOUSE RING finger protein 38 OS=Mus mus...510.65     38.1     31     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
677P29129    410   ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 O...420.67     38.1     36     48
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
678Q9P0P0    153   RN181_HUMAN E3 ubiquitin-protein ligase RNF18...440.67     36.6     41     52
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
679Q3TL54    445   TR43A_MOUSE Tripartite motif-containing prote...530.68     38.1     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
680Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...390.71     38.1     41     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
681P18541    90   Z_LYCVA RING finger protein Z OS=Lymphocytic ...420.73     35.4     33     57GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
682Q8RXD6    878   BRE1A_ARATH E3 ubiquitin-protein ligase BRE1-...720.73     38.1     31     47GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0033523; P:histone H2B ubiquitination; IMP:TAIR.::GO:0010390; P:histone monoubiquitination; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0010162; P:seed dormancy process; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
683Q9NZS9    450   BFAR_HUMAN Bifunctional apoptosis regulator O...1040.76     37.7     26     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005198; F:structural molecule activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
684Q8IYM9    498   TRI22_HUMAN E3 ubiquitin-protein ligase TRIM2...480.76     37.7     33     52GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006955; P:immune response; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
685O74563    680   BRL2_SCHPO E3 ubiquitin-protein ligase brl2 O...440.77     38.1     43     52GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.
686Q86TM6    617   SYVN1_HUMAN E3 ubiquitin-protein ligase synov...400.79     38.1     38     53GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
687Q02398    443   RAD18_EMENI Postreplication repair E3 ubiquit...410.81     37.7     37     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
688Q9DBY1    612   SYVN1_MOUSE E3 ubiquitin-protein ligase synov...400.81     37.7     38     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.
689A6NGJ6    449   TRI64_HUMAN Tripartite motif-containing prote...790.82     37.7     32     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
690Q32L60    407   TRI13_BOVIN E3 ubiquitin-protein ligase TRIM1...830.85     37.7     28     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
691Q9GQN5    1311   ATRX_DROME Transcriptional regulator ATRX hom...630.94     37.7     25     54GO:0005722; C:beta-heterochromatin; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:FlyBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0070868; P:heterochromatin organization involved in chromatin silencing; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0046328; P:regulation of JNK cascade; IGI:FlyBase.
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