Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR247C
Length:
1556
Number of sequences:
5887
Description:
YLR247C IRC20 SGDID:S000004237, Chr XII from 633354-628684, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q9BZY9    425   TRI31_HUMAN E3 ubiquitin-protein ligase TRIM3...800.35     38.9     34     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
632Q9EPZ8    682   RN103_RAT E3 ubiquitin-protein ligase RNF103 ...430.35     39.3     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
633Q96EH8    262   NEUL3_HUMAN E3 ubiquitin-protein ligase NEURL...400.36     38.5     35     53
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
634Q9R1W3    683   RN103_MOUSE E3 ubiquitin-protein ligase RNF10...430.36     39.3     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
635Q810I1    483   TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ...440.36     38.9     34     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
636Q91431    610   NF7O_XENLA Nuclear factor 7, ovary OS=Xenopus...430.36     38.9     37     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
637Q9ULV8    474   CBLC_HUMAN Signal transduction protein CBL-C ...800.36     38.9     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.::GO:0001784; F:phosphotyrosine binding; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
638Q14258    630   TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ...450.36     38.9     44     51GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
639Q8CIK8    774   RFWD3_MOUSE E3 ubiquitin-protein ligase RFWD3...540.37     39.3     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
640Q9C7E9    299   ATL20_ARATH RING-H2 finger protein ATL20 OS=A...430.38     38.5     40     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
641P62603    542   TRI26_RAT Tripartite motif-containing protein...450.38     38.9     42     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
642Q8LDB8    381   RING2_ARATH E3 ubiquitin-protein ligase At1g6...420.39     38.5     38     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
643Q9Y252    685   RNF6_HUMAN E3 ubiquitin-protein ligase RNF6 O...420.39     38.9     36     52GO:0030424; C:axon; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030517; P:negative regulation of axon extension; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
644Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...660.4     38.9     33     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
645Q9BVG3    475   TRI62_HUMAN Tripartite motif-containing prote...660.4     38.9     33     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
646Q9V8P9    1038   TOPRS_DROME E3 ubiquitin-protein ligase Topor...400.4     39.3     35     48GO:0005652; C:nuclear lamina; IDA:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:UniProtKB.
GO:0005521; F:lamin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006997; P:nucleus organization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
647Q8IWR1    403   TRI59_HUMAN Tripartite motif-containing prote...820.4     38.5     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
648Q8HXH0    718   LONF3_MACFA LON peptidase N-terminal domain a...450.41     38.9     36     51
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
649O00237    685   RN103_HUMAN E3 ubiquitin-protein ligase RNF10...430.42     38.9     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
650Q496Y0    759   LONF3_HUMAN LON peptidase N-terminal domain a...450.42     38.9     36     51
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
651Q6PCD5    774   RFWD3_HUMAN E3 ubiquitin-protein ligase RFWD3...460.43     38.9     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
652Q8R079    450   BFAR_MOUSE Bifunctional apoptosis regulator O...1040.45     38.5     25     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
653Q5E9G4    489   TRI10_BOVIN Tripartite motif-containing prote...480.45     38.5     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
654Q66J69    344   RNG2A_XENLA E3 ubiquitin-protein ligase RING2...430.48     38.1     44     58GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
655Q75DC2    328   ASR1_ASHGO Alcohol-sensitive RING finger prot...490.49     38.1     35     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
656Q08CG8    448   RNF44_DANRE RING finger protein 44 OS=Danio r...510.51     38.5     31     51
GO:0008270; F:zinc ion binding; IEA:InterPro.
657Q8BGI1    148   RNF24_MOUSE RING finger protein 24 OS=Mus mus...420.51     36.6     36     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
658Q6NRL6    605   SYVNA_XENLA E3 ubiquitin-protein ligase synov...400.51     38.5     38     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
659Q4P400    355   CWC24_USTMA Pre-mRNA-splicing factor CWC24 OS...540.51     38.1     33     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
660Q6MFY8    247   TRI40_RAT Tripartite motif-containing protein...540.52     37.7     33     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
661B5DF45    530   TRAF6_RAT TNF receptor-associated factor 6 OS...380.53     38.5     45     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
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