rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q4KLY4 | 308 | RING2_RAT E3 ubiquitin-protein ligase RING2 O... | 43 | 0.18 | 39.7 | 44 | 58 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016567; P:protein ubiquitination; ISS:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 572 | O77666 | 545 | TRI26_PIG Tripartite motif-containing protein... | 44 | 0.18 | 40 | 41 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 573 | Q80XL1 | 496 | CBLC_MOUSE Signal transduction protein CBL-C ... | 83 | 0.18 | 40 | 30 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro. | 574 | Q9NS91 | 495 | RAD18_HUMAN E3 ubiquitin-protein ligase RAD18... | 48 | 0.18 | 40 | 38 | 54 | GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005657; C:replication fork; IDA:UniProtKB. | | | | | | | | | | GO:0003684; F:damaged DNA binding; NAS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; NAS:UniProtKB. | 575 | P87237 | 821 | YC0C_SCHPO Uncharacterized RING finger protei... | 46 | 0.18 | 40 | 37 | 54 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 576 | Q90ZT7 | 923 | R111A_XENLA E3 ubiquitin-protein ligase arkad... | 42 | 0.18 | 40 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 577 | Q8CHI8 | 3072 | EP400_MOUSE E1A-binding protein p400 OS=Mus m... | 171 | 0.18 | 40.4 | 22 | 47 | GO:0035267; C:NuA4 histone acetyltransferase complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043968; P:histone H2A acetylation; ISS:UniProtKB.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB. | 578 | Q9P6R8 | 533 | CWC24_SCHPO Pre-mRNA-splicing factor cwf24 OS... | 69 | 0.19 | 40 | 28 | 46 | GO:0005681; C:spliceosomal complex; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; TAS:PomBase.::GO:0016074; P:snoRNA metabolic process; NAS:PomBase. | 579 | Q9LSW9 | 375 | ATL16_ARATH RING-H2 finger protein ATL16 OS=A... | 43 | 0.19 | 39.7 | 37 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 580 | Q803I4 | 336 | RING2_DANRE E3 ubiquitin-protein ligase RING2... | 43 | 0.19 | 39.7 | 44 | 58 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 581 | Q9H0F5 | 515 | RNF38_HUMAN RING finger protein 38 OS=Homo sa... | 51 | 0.2 | 39.7 | 33 | 55 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 582 | Q6CHI1 | 344 | RAD18_YARLI Postreplication repair E3 ubiquit... | 63 | 0.2 | 39.7 | 38 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 583 | B6CJY5 | 522 | TRAF6_MACMU TNF receptor-associated factor 6 ... | 105 | 0.2 | 39.7 | 31 | 48 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 584 | Q9VB08 | 435 | RING1_DROME E3 ubiquitin-protein ligase RING1... | 43 | 0.2 | 39.7 | 44 | 58 | GO:0008278; C:cohesin complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; TAS:FlyBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IDA:UniProtKB.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0022008; P:neurogenesis; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0045498; P:sex comb development; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 585 | Q9QXK2 | 509 | RAD18_MOUSE E3 ubiquitin-protein ligase RAD18... | 48 | 0.21 | 39.7 | 38 | 54 | GO:0000785; C:chromatin; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001741; C:XY body; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.::GO:0009411; P:response to UV; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 586 | Q9P7E1 | 583 | YOF7_SCHPO Uncharacterized RING finger protei... | 52 | 0.21 | 39.7 | 35 | 52 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 587 | P70196 | 530 | TRAF6_MOUSE TNF receptor-associated factor 6 ... | 38 | 0.21 | 39.7 | 45 | 58 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0004871; F:signal transducer activity; TAS:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.::GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0048468; P:cell development; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IMP:MGI.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0051023; P:regulation of immunoglobulin secretion; IDA:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI. | 588 | Q6ZNA4 | 994 | RN111_HUMAN E3 ubiquitin-protein ligase Arkad... | 42 | 0.21 | 40 | 40 | 60 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:BHF-UCL. | 589 | Q99NA9 | 353 | PCGF6_MOUSE Polycomb group RING finger protei... | 39 | 0.23 | 39.3 | 44 | 59 | GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 590 | Q3KNV8 | 242 | PCGF3_HUMAN Polycomb group RING finger protei... | 45 | 0.23 | 38.9 | 31 | 62 | GO:0031519; C:PcG protein complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 591 | Q752S4 | 250 | CWC24_ASHGO Pre-mRNA-splicing factor CWC24 OS... | 44 | 0.23 | 38.9 | 32 | 45 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 592 | Q5XIL0 | 349 | RN167_RAT E3 ubiquitin-protein ligase RNF167 ... | 43 | 0.23 | 39.3 | 44 | 53 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 593 | Q3ZCC3 | 542 | TRAF6_BOVIN TNF receptor-associated factor 6 ... | 38 | 0.23 | 39.7 | 45 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 594 | Q86UV6 | 250 | TRI74_HUMAN Tripartite motif-containing prote... | 43 | 0.23 | 38.9 | 35 | 58 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 595 | Q28GL3 | 416 | RNFT1_XENTR RING finger and transmembrane dom... | 39 | 0.24 | 39.3 | 36 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 596 | Q62191 | 470 | RO52_MOUSE E3 ubiquitin-protein ligase TRIM21... | 42 | 0.24 | 39.7 | 43 | 57 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 597 | Q9D4H7 | 753 | LONF3_MOUSE LON peptidase N-terminal domain a... | 45 | 0.24 | 39.7 | 38 | 51 | | | | | | | | | | | GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 598 | B6CJY4 | 522 | TRAF6_CERAT TNF receptor-associated factor 6 ... | 38 | 0.25 | 39.7 | 45 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 599 | Q5R476 | 986 | RN111_PONAB E3 ubiquitin-protein ligase Arkad... | 42 | 0.25 | 39.7 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 600 | Q99ML9 | 989 | RN111_MOUSE E3 ubiquitin-protein ligase Arkad... | 42 | 0.25 | 39.7 | 40 | 60 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007389; P:pattern specification process; IMP:MGI.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IMP:BHF-UCL.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IMP:BHF-UCL. | 601 | Q9Y4K3 | 522 | TRAF6_HUMAN TNF receptor-associated factor 6 ... | 38 | 0.25 | 39.7 | 45 | 58 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. |