Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR247C
Length:
1556
Number of sequences:
5887
Description:
YLR247C IRC20 SGDID:S000004237, Chr XII from 633354-628684, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571Q4KLY4    308   RING2_RAT E3 ubiquitin-protein ligase RING2 O...430.18     39.7     44     58GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0016567; P:protein ubiquitination; ISS:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
572O77666    545   TRI26_PIG Tripartite motif-containing protein...440.18     40     41     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
573Q80XL1    496   CBLC_MOUSE Signal transduction protein CBL-C ...830.18     40     30     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
574Q9NS91    495   RAD18_HUMAN E3 ubiquitin-protein ligase RAD18...480.18     40     38     54GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005657; C:replication fork; IDA:UniProtKB.
GO:0003684; F:damaged DNA binding; NAS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; NAS:UniProtKB.
575P87237    821   YC0C_SCHPO Uncharacterized RING finger protei...460.18     40     37     54
GO:0008270; F:zinc ion binding; IEA:InterPro.
576Q90ZT7    923   R111A_XENLA E3 ubiquitin-protein ligase arkad...420.18     40     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
577Q8CHI8    3072   EP400_MOUSE E1A-binding protein p400 OS=Mus m...1710.18     40.4     22     47GO:0035267; C:NuA4 histone acetyltransferase complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043968; P:histone H2A acetylation; ISS:UniProtKB.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.
578Q9P6R8    533   CWC24_SCHPO Pre-mRNA-splicing factor cwf24 OS...690.19     40     28     46GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; TAS:PomBase.::GO:0016074; P:snoRNA metabolic process; NAS:PomBase.
579Q9LSW9    375   ATL16_ARATH RING-H2 finger protein ATL16 OS=A...430.19     39.7     37     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
580Q803I4    336   RING2_DANRE E3 ubiquitin-protein ligase RING2...430.19     39.7     44     58GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
581Q9H0F5    515   RNF38_HUMAN RING finger protein 38 OS=Homo sa...510.2     39.7     33     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
582Q6CHI1    344   RAD18_YARLI Postreplication repair E3 ubiquit...630.2     39.7     38     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
583B6CJY5    522   TRAF6_MACMU TNF receptor-associated factor 6 ...1050.2     39.7     31     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
584Q9VB08    435   RING1_DROME E3 ubiquitin-protein ligase RING1...430.2     39.7     44     58GO:0008278; C:cohesin complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; TAS:FlyBase.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; IDA:UniProtKB.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0022008; P:neurogenesis; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0045498; P:sex comb development; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
585Q9QXK2    509   RAD18_MOUSE E3 ubiquitin-protein ligase RAD18...480.21     39.7     38     54GO:0000785; C:chromatin; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001741; C:XY body; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.::GO:0009411; P:response to UV; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.
586Q9P7E1    583   YOF7_SCHPO Uncharacterized RING finger protei...520.21     39.7     35     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
587P70196    530   TRAF6_MOUSE TNF receptor-associated factor 6 ...380.21     39.7     45     58GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0004871; F:signal transducer activity; TAS:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.::GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0048468; P:cell development; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IMP:MGI.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0051023; P:regulation of immunoglobulin secretion; IDA:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI.
588Q6ZNA4    994   RN111_HUMAN E3 ubiquitin-protein ligase Arkad...420.21     40     40     60GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:BHF-UCL.
589Q99NA9    353   PCGF6_MOUSE Polycomb group RING finger protei...390.23     39.3     44     59GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
590Q3KNV8    242   PCGF3_HUMAN Polycomb group RING finger protei...450.23     38.9     31     62GO:0031519; C:PcG protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
591Q752S4    250   CWC24_ASHGO Pre-mRNA-splicing factor CWC24 OS...440.23     38.9     32     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
592Q5XIL0    349   RN167_RAT E3 ubiquitin-protein ligase RNF167 ...430.23     39.3     44     53GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
593Q3ZCC3    542   TRAF6_BOVIN TNF receptor-associated factor 6 ...380.23     39.7     45     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
594Q86UV6    250   TRI74_HUMAN Tripartite motif-containing prote...430.23     38.9     35     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
595Q28GL3    416   RNFT1_XENTR RING finger and transmembrane dom...390.24     39.3     36     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
596Q62191    470   RO52_MOUSE E3 ubiquitin-protein ligase TRIM21...420.24     39.7     43     57GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
597Q9D4H7    753   LONF3_MOUSE LON peptidase N-terminal domain a...450.24     39.7     38     51
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
598B6CJY4    522   TRAF6_CERAT TNF receptor-associated factor 6 ...380.25     39.7     45     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
599Q5R476    986   RN111_PONAB E3 ubiquitin-protein ligase Arkad...420.25     39.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
600Q99ML9    989   RN111_MOUSE E3 ubiquitin-protein ligase Arkad...420.25     39.7     40     60GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:MGI.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007389; P:pattern specification process; IMP:MGI.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IMP:BHF-UCL.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IMP:BHF-UCL.
601Q9Y4K3    522   TRAF6_HUMAN TNF receptor-associated factor 6 ...380.25     39.7     45     58GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
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