Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR247C
Length:
1556
Number of sequences:
5887
Description:
YLR247C IRC20 SGDID:S000004237, Chr XII from 633354-628684, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q2HJ46    487   RNF8_BOVIN E3 ubiquitin-protein ligase RNF8 O...540.021     43.1     35     48GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
422Q9M313    212   ATL68_ARATH RING-H2 finger protein ATL68 OS=A...810.021     42     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
423B5DE69    2184   CHD8_XENTR Chromodomain-helicase-DNA-binding ...1430.022     43.5     25     42GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
424Q5Z5F2    251   ATL61_ORYSJ E3 ubiquitin-protein ligase Os06g...430.022     42     44     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
425Q8BZT2    735   SH3R2_MOUSE Putative E3 ubiquitin-protein lig...490.023     43.1     37     59
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
426E9Q555    5150   RN213_MOUSE E3 ubiquitin-protein ligase RNF21...940.024     43.1     29     40GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
427Q8L9T5    304   ATL2_ARATH RING-H2 finger protein ATL2 OS=Ara...700.024     42.4     30     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IDA:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
428Q9XFH4    764   DDM1_ARATH ATP-dependent DNA helicase DDM1 OS...1074.1     35.8     24     41GO:0000786; C:nucleosome; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IMP:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006344; P:maintenance of chromatin silencing; IMP:UniProtKB.::GO:0006346; P:methylation-dependent chromatin silencing; IMP:TAIR.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:UniProtKB.::GO:0044030; P:regulation of DNA methylation; IMP:UniProtKB.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0032197; P:transposition, RNA-mediated; IMP:TAIR.
429Q498M5    735   SH3R2_RAT Putative E3 ubiquitin-protein ligas...490.026     42.7     37     59
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
430Q4V7B8    350   RNF44_RAT RING finger protein 44 OS=Rattus no...530.026     42.4     32     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
431Q5R4I2    486   RNF8_PONAB E3 ubiquitin-protein ligase RNF8 O...550.026     42.7     40     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
432Q495X7    471   TRI60_HUMAN Tripartite motif-containing prote...1030.026     42.7     32     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
433Q9D304    428   RN128_MOUSE E3 ubiquitin-protein ligase RNF12...860.027     42.4     28     45GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042036; P:negative regulation of cytokine biosynthetic process; IDA:MGI.
434P93030    193   RMA2_ARATH E3 ubiquitin-protein ligase RMA2 O...570.028     41.2     33     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
435O76064    485   RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 O...550.028     42.7     40     55GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
436Q6ZMN7    1036   PZRN4_HUMAN PDZ domain-containing RING finger...390.028     42.7     38     51
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
437Q95KF1    232   RN125_MACFA E3 ubiquitin-protein ligase RNF12...440.028     41.6     36     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
438Q9FKW0    522   RNG1A_ARATH Putative E3 ubiquitin-protein lig...470.028     42.7     34     62GO:0035102; C:PRC1 complex; IPI:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010076; P:maintenance of floral meristem identity; IMP:UniProtKB.::GO:0010077; P:maintenance of inflorescence meristem identity; IMP:UniProtKB.::GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IGI:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
439Q96EQ8    232   RN125_HUMAN E3 ubiquitin-protein ligase RNF12...590.029     41.6     32     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
440Q3UHJ8    407   RNF44_MOUSE RING finger protein 44 OS=Mus mus...530.029     42.4     32     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
441P84445    532   ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 O...400.029     42.7     40     53
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
442P28990    532   ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 O...400.029     42.7     40     53
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
443Q96K19    258   RN170_HUMAN RING finger protein 170 OS=Homo s...470.029     42     40     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
444Q86KL1    1080   BRE1_DICDI Probable E3 ubiquitin-protein liga...560.031     42.7     34     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
445Q8GW38    369   ATL47_ARATH RING-H2 finger protein ATL47 OS=A...440.032     42     39     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
446Q2TA44    303   RN148_BOVIN RING finger protein 148 OS=Bos ta...480.033     42     40     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
447Q9U7E0    1359   ATRX_CAEEL Transcriptional regulator ATRX hom...3080.23     40     20     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
448Q336R3    844   BRE1B_ORYSJ E3 ubiquitin-protein ligase BRE1-...690.035     42.4     33     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
449A2ZAC2    844   BRE1B_ORYSI E3 ubiquitin-protein ligase BRE1-...690.035     42.4     33     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
450Q9WTV7    600   RNF12_MOUSE E3 ubiquitin-protein ligase RLIM ...480.035     42.4     33     56GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
451Q9NVW2    624   RNF12_HUMAN E3 ubiquitin-protein ligase RLIM ...480.037     42.4     33     56GO:0005737; C:cytoplasm; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; NAS:UniProtKB.
GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
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