Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR247C
Length:
1556
Number of sequences:
5887
Description:
YLR247C IRC20 SGDID:S000004237, Chr XII from 633354-628684, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271F7H9X2    744   TRIM2_CALJA Tripartite motif-containing prote...480.002     46.6     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
272Q6GPV5    156   RN181_XENLA E3 ubiquitin-protein ligase RNF18...670.002     44.3     31     49
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
273D3ZQG6    744   TRIM2_RAT Tripartite motif-containing protein...480.002     46.6     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; IMP:UniProtKB.
274Q9ESN6    744   TRIM2_MOUSE Tripartite motif-containing prote...480.002     46.6     40     58GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0017022; F:myosin binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0043526; P:neuroprotection; IMP:UniProtKB.
275Q9ZV53    423   ATL49_ARATH Putative RING-H2 finger protein A...520.002     46.2     42     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
276P09309    467   IE61_VZVD E3 ubiquitin-protein ligase IE61 OS...720.002     46.2     29     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
277Q864U1    1849   BRCA1_BOVIN Breast cancer type 1 susceptibili...590.002     47     39     58GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
278C0H4W3    2082   HEPF1_PLAF7 Probable ATP-dependent helicase P...2150.029     43.1     25     42GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016020; C:membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; ISS:GeneDB_Pfalciparum.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
279Q9Y6U7    377   RN215_HUMAN RING finger protein 215 OS=Homo s...880.002     46.2     31     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
280Q69ZS0    1063   PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN...500.002     46.6     36     50GO:0031594; C:neuromuscular junction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007528; P:neuromuscular junction development; IMP:UniProtKB.
281Q63625    1685   PHRF1_RAT PHD and RING finger domain-containi...470.002     46.6     38     53
GO:0019904; F:protein domain specific binding; IMP:RGD.::GO:0070063; F:RNA polymerase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IMP:RGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IMP:RGD.
282Q6DIC0    1577   SMCA2_MOUSE Probable global transcription act...1150.003     46.2     29     49GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0016514; C:SWI/SNF complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; TAS:MGI.
283Q9UPQ7    1066   PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN...500.002     46.6     36     50
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
284Q9FHG8    210   ATL50_ARATH Putative RING-H2 finger protein A...640.002     44.7     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
285P51531    1590   SMCA2_HUMAN Probable global transcription act...1150.004     45.8     29     49GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; TAS:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
286Q9DCN7    395   RNFT1_MOUSE RING finger and transmembrane dom...540.002     45.8     37     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
287O75382    744   TRIM3_HUMAN Tripartite motif-containing prote...480.002     46.2     38     56GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
288Q9SJJ7    237   ATL57_ARATH RING-H2 finger protein ATL57 OS=A...430.002     45.1     42     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
289Q5REG4    347   DTX3_PONAB Probable E3 ubiquitin-protein liga...480.002     45.8     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
290Q8N9I9    347   DTX3_HUMAN Probable E3 ubiquitin-protein liga...480.002     45.8     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
291Q6J6J0    1863   BRCA1_PONPY Breast cancer type 1 susceptibili...460.003     46.6     43     59GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
292Q7ZX20    540   RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-...1590.003     45.8     27     41GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
293Q640D5    323   BMI1B_XENLA Polycomb complex protein BMI-1-B ...440.003     45.4     43     59GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
294Q8GT74    241   NIP2_ARATH NEP1-interacting protein 2 OS=Arab...440.003     45.1     39     57GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0031351; C:integral to plastid membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009299; P:mRNA transcription; IPI:TAIR.::GO:0009416; P:response to light stimulus; IEP:TAIR.
295P38398    1863   BRCA1_HUMAN Breast cancer type 1 susceptibili...460.003     46.2     43     59GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:MGI.::GO:0000724; P:double-strand break repair via homologous recombination; IDA:HGNC.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:UniProtKB.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IDA:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IDA:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006301; P:postreplication repair; IDA:HGNC.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:2000145; P:regulation of cell motility; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
296P75093    1030   Y020_MYCPN Uncharacterized ATP-dependent heli...1820.004     45.8     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
297P0C035    310   ATL60_ARATH RING-H2 finger protein ATL60 OS=A...750.003     45.4     31     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
298G3X9R7    316   RN148_MOUSE RING finger protein 148 OS=Mus mu...480.003     45.4     42     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
299Q9GKK8    1863   BRCA1_PANTR Breast cancer type 1 susceptibili...460.003     46.2     43     59GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.
300Q9FG21    197   ATL71_ARATH Putative RING-H2 finger protein A...430.003     44.3     40     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
301Q8GT75    236   NIP1_ARATH NEP1-interacting protein 1 OS=Arab...440.003     44.7     39     57GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
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