rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q59LR2 | 2325 | ATR_CANAL Serine/threonine-protein kinase MEC... | 299 | 0.000000007 | 63.5 | 22 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 92 | P97313 | 4128 | PRKDC_MOUSE DNA-dependent protein kinase cata... | 236 | 0.00000001 | 62.8 | 25 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0002326; P:B cell lineage commitment; IMP:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.::GO:0035234; P:germ cell programmed cell death; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0033152; P:immunoglobulin V(D)J recombination; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002328; P:pro-B cell differentiation; IMP:MGI.::GO:0031648; P:protein destabilization; IDA:MGI.::GO:0010332; P:response to gamma radiation; IMP:MGI.::GO:0001756; P:somitogenesis; IGI:MGI.::GO:0033077; P:T cell differentiation in thymus; IMP:MGI.::GO:0002360; P:T cell lineage commitment; IMP:MGI.::GO:0033153; P:T cell receptor V(D)J recombination; IMP:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI. | 93 | Q8SSE7 | 1935 | ATR_ENCCU Probable serine/threonine-protein k... | 293 | 0.00000002 | 62.4 | 26 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 94 | Q2U639 | 2925 | ATM_ASPOR Serine/threonine-protein kinase tel... | 249 | 0.00000002 | 62.4 | 22 | 39 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 95 | Q4IB89 | 2813 | ATM_GIBZE Serine/threonine-protein kinase TEL... | 263 | 0.00000007 | 60.5 | 23 | 38 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 96 | Q5ABX0 | 2873 | ATM_CANAL Serine/threonine-protein kinase TEL... | 243 | 0.0000001 | 60.1 | 23 | 40 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 97 | Q9VXG8 | 2517 | ATR_DROME Serine/threonine-protein kinase ATR... | 263 | 0.0000001 | 59.7 | 23 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030261; P:chromosome condensation; IGI:FlyBase.::GO:0000076; P:DNA replication checkpoint; IMP:FlyBase.::GO:0045002; P:double-strand break repair via single-strand annealing; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007133; P:meiotic anaphase I; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; TAS:FlyBase.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0000723; P:telomere maintenance; IGI:FlyBase. | 98 | O14356 | 2335 | TOR1_SCHPO Phosphatidylinositol 3-kinase tor1... | 264 | 0.0000002 | 58.5 | 24 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007569; P:cell aging; TAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0043091; P:L-arginine import; IMP:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0060357; P:regulation of leucine import; IMP:PomBase.::GO:0009266; P:response to temperature stimulus; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 99 | P78527 | 4128 | PRKDC_HUMAN DNA-dependent protein kinase cata... | 237 | 0.0000003 | 58.5 | 25 | 38 | GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004677; F:DNA-dependent protein kinase activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 100 | Q9M3G7 | 3856 | ATM_ARATH Serine/threonine-protein kinase ATM... | 270 | 0.0000004 | 58.2 | 25 | 38 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; TAS:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IMP:TAIR.::GO:0007126; P:meiosis; IMP:TAIR.::GO:0032504; P:multicellular organism reproduction; IGI:TAIR.::GO:0032204; P:regulation of telomere maintenance; IGI:TAIR.::GO:0010332; P:response to gamma radiation; IMP:TAIR.::GO:0043247; P:telomere maintenance in response to DNA damage; TAS:TAIR. | 101 | Q9Y7K2 | 2337 | TOR2_SCHPO Phosphatidylinositol 3-kinase tor2... | 288 | 0.000001 | 56.6 | 24 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0034064; C:Tor2-Mei2-Ste11 complex; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0031670; P:cellular response to nutrient; NAS:PomBase.::GO:0010507; P:negative regulation of autophagy; IMP:PomBase.::GO:0010503; P:negative regulation of cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0010515; P:negative regulation of induction of conjugation with cellular fusion; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 102 | Q8QGX4 | 4134 | PRKDC_CHICK DNA-dependent protein kinase cata... | 233 | 0.000001 | 56.6 | 24 | 40 | GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome. | 103 | Q54UC0 | 4299 | PRKDC_DICDI DNA-dependent protein kinase cata... | 63 | 0.036 | 41.6 | 37 | 59 | GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006975; P:DNA damage induced protein phosphorylation; IMP:dictyBase.::GO:0006310; P:DNA recombination; ISS:dictyBase.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro. | 104 | Q13315 | 3056 | ATM_HUMAN Serine-protein kinase ATM OS=Homo s... | 258 | 0.00001 | 53.1 | 24 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004677; F:DNA-dependent protein kinase activity; IDA:BHF-UCL.::GO:0032403; F:protein complex binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IDA:BHF-UCL.::GO:0047485; F:protein N-terminus binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.::GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.::GO:0006975; P:DNA damage induced protein phosphorylation; IDA:BHF-UCL.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:BHF-UCL.::GO:0071044; P:histone mRNA catabolic process; IDA:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.::GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.::GO:0090399; P:replicative senescence; IMP:BHF-UCL. | 105 | Q62388 | 3066 | ATM_MOUSE Serine-protein kinase ATM OS=Mus mu... | 263 | 0.00001 | 53.1 | 22 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IGI:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0007292; P:female gamete generation; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0042159; P:lipoprotein catabolic process; IGI:MGI.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; IGI:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0001756; P:somitogenesis; IGI:MGI. | 106 | O74630 | 2812 | ATM_SCHPO Serine/threonine-protein kinase tel... | 268 | 0.00002 | 52.8 | 24 | 40 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; NAS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016572; P:histone phosphorylation; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 107 | Q13535 | 2644 | ATR_HUMAN Serine/threonine-protein kinase ATR... | 248 | 0.00002 | 52 | 24 | 41 | GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0032405; F:MutLalpha complex binding; IDA:MGI.::GO:0032407; F:MutSalpha complex binding; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0007049; P:cell cycle; TAS:ProtInc.::GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.::GO:0034644; P:cellular response to UV; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.::GO:0006281; P:DNA repair; TAS:Reactome.::GO:0006260; P:DNA replication; TAS:Reactome.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0090399; P:replicative senescence; IMP:BHF-UCL. | 108 | Q6PQD5 | 3057 | ATM_PIG Serine-protein kinase ATM OS=Sus scro... | 258 | 0.00002 | 52 | 24 | 38 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro. | 109 | P0CP61 | 2968 | ATM_CRYNB Serine/threonine-protein kinase TEL... | 245 | 0.00003 | 52 | 24 | 40 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 110 | Q5EAK6 | 2767 | ATM_DROME Serine/threonine-protein kinase ATM... | 260 | 0.00003 | 52 | 22 | 35 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006348; P:chromatin silencing at telomere; IMP:FlyBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045494; P:photoreceptor cell maintenance; IMP:FlyBase.::GO:0016233; P:telomere capping; IMP:FlyBase. | 111 | Q9JKK8 | 2635 | ATR_MOUSE Serine/threonine-protein kinase ATR... | 343 | 0.00003 | 52 | 23 | 40 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 112 | P0CP60 | 2967 | ATM_CRYNJ Serine/threonine-protein kinase TEL... | 245 | 0.00003 | 51.6 | 24 | 40 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 113 | O01510 | 2322 | SMG1_CAEEL Serine/threonine-protein kinase sm... | 107 | 0.0002 | 48.9 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IGI:WormBase. | 114 | Q61CW2 | 2313 | SMG1_CAEBR Serine/threonine-protein kinase sm... | 78 | 2.2 | 35.8 | 26 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW. | 115 | Q9DE14 | 2654 | ATR_XENLA Serine/threonine-protein kinase atr... | 248 | 0.0003 | 48.5 | 24 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB. | 116 | Q553E9 | 2344 | SMG1_DICDI Probable serine/threonine-protein ... | 107 | 0.0004 | 48.1 | 33 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW. | 117 | Q8BKX6 | 3658 | SMG1_MOUSE Serine/threonine-protein kinase SM... | 109 | 0.0004 | 48.1 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW. | 118 | Q96Q15 | 3661 | SMG1_HUMAN Serine/threonine-protein kinase SM... | 109 | 0.0004 | 48.1 | 30 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 119 | Q9DEI1 | 4146 | PRKDC_XENLA DNA-dependent protein kinase cata... | 85 | 0.064 | 40.8 | 28 | 49 | GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro. | 120 | Q8WN22 | 4144 | PRKDC_CANFA DNA-dependent protein kinase cata... | 85 | 0.001 | 46.6 | 33 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro. | 121 | Q70PP2 | 3218 | SMG1_DROME Serine/threonine-protein kinase Sm... | 99 | 0.13 | 40 | 24 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0048489; P:synaptic vesicle transport; IDA:FlyBase. |