rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P13099 | 656 | TOP3_YEAST DNA topoisomerase 3 OS=Saccharomyc... | 656 | 0 | 1381 | 100 | 100 | GO:0005634; C:nucleus; IC:SGD.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IDA:SGD. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0000018; P:regulation of DNA recombination; IMP:SGD.::GO:0007004; P:telomere maintenance via telomerase; IMP:SGD. | 2 | O60126 | 622 | TOP3_SCHPO DNA topoisomerase 3 OS=Schizosacch... | 656 | 0 | 541 | 44 | 61 | GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.::GO:0031422; C:RecQ helicase-Topo III complex; TAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0043007; P:maintenance of rDNA; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0045910; P:negative regulation of DNA recombination; TAS:PomBase.::GO:0007000; P:nucleolus organization; IMP:PomBase.::GO:0031297; P:replication fork processing; NAS:PomBase.::GO:0000712; P:resolution of meiotic recombination intermediates; TAS:PomBase. | 3 | Q13472 | 1001 | TOP3A_HUMAN DNA topoisomerase 3-alpha OS=Homo... | 634 | 9e-147 | 458 | 42 | 58 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007126; P:meiosis; TAS:ProtInc. | 4 | O70157 | 1003 | TOP3A_MOUSE DNA topoisomerase 3-alpha OS=Mus ... | 635 | 7e-146 | 456 | 41 | 59 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 5 | Q8T2T7 | 828 | TOP3_DICDI DNA topoisomerase 3 OS=Dictyosteli... | 652 | 1e-143 | 445 | 38 | 57 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 6 | O61660 | 759 | TOP3_CAEEL DNA topoisomerase 3 OS=Caenorhabdi... | 631 | 3e-141 | 437 | 40 | 57 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007276; P:gamete generation; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase. | 7 | Q9NG98 | 1250 | TOP3A_DROME DNA topoisomerase 3-alpha OS=Dros... | 639 | 8e-121 | 395 | 37 | 54 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:FlyBase. | 8 | O95985 | 862 | TOP3B_HUMAN DNA topoisomerase 3-beta-1 OS=Hom... | 644 | 2e-96 | 322 | 34 | 48 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 9 | O96651 | 875 | TOP3B_DROME DNA topoisomerase 3-beta OS=Droso... | 637 | 2e-94 | 316 | 33 | 49 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0004520; F:endodeoxyribonuclease activity; IDA:FlyBase. | | | | | | | | | | GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:FlyBase.::GO:0006265; P:DNA topological change; IEA:InterPro. | 10 | Q9Z321 | 862 | TOP3B_MOUSE DNA topoisomerase 3-beta-1 OS=Mus... | 640 | 4e-94 | 315 | 33 | 49 | GO:0000793; C:condensed chromosome; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:MGI.::GO:0006265; P:DNA topological change; IEA:InterPro. | 11 | O28469 | 663 | TOP1_ARCFU DNA topoisomerase 1 OS=9628 / NBRC... | 630 | 9e-50 | 188 | 26 | 44 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 12 | Q9HM08 | 770 | TOP1_THEAC DNA topoisomerase 1 OS=NBRC 15155 ... | 625 | 5e-47 | 181 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 13 | Q59046 | 761 | TOP1_METJA DNA topoisomerase 1 OS=JCM 10045 /... | 639 | 1e-44 | 174 | 26 | 46 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 14 | Q9UYS8 | 685 | TOP1_PYRAB DNA topoisomerase 1 OS=Pyrococcus ... | 647 | 2e-44 | 172 | 25 | 45 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 15 | O58356 | 686 | TOP1_PYRHO DNA topoisomerase 1 OS=NBRC 100139... | 640 | 4e-44 | 171 | 24 | 44 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 16 | O27661 | 718 | TOP1_METTH DNA topoisomerase 1 OS=thermoautot... | 589 | 1e-41 | 164 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 17 | P43012 | 868 | TOP1_HAEIN DNA topoisomerase 1 OS=Haemophilus... | 484 | 2e-30 | 131 | 26 | 44 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 18 | Q9PLZ2 | 700 | TOP1_CAMJE DNA topoisomerase 1 OS=Campylobact... | 493 | 2e-27 | 121 | 25 | 43 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 19 | Q9CN30 | 868 | TOP1_PASMU DNA topoisomerase 1 OS=Pasteurella... | 479 | 6e-27 | 120 | 25 | 44 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 20 | Q5HGI2 | 689 | TOP1_STAAC DNA topoisomerase 1 OS=Staphylococ... | 503 | 2e-26 | 118 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 21 | Q2FZ32 | 689 | TOP1_STAA8 DNA topoisomerase 1 OS=Staphylococ... | 503 | 2e-26 | 118 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 22 | Q2FHI8 | 689 | TOP1_STAA3 DNA topoisomerase 1 OS=Staphylococ... | 503 | 2e-26 | 118 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 23 | Q2YXL8 | 689 | TOP1_STAAB DNA topoisomerase 1 OS=Staphylococ... | 503 | 3e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 24 | Q8NWZ9 | 689 | TOP1_STAAW DNA topoisomerase 1 OS=Staphylococ... | 503 | 4e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 25 | Q6G9W3 | 689 | TOP1_STAAS DNA topoisomerase 1 OS=Staphylococ... | 503 | 4e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 26 | Q6GHI5 | 689 | TOP1_STAAR DNA topoisomerase 1 OS=Staphylococ... | 503 | 4e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 27 | Q7A5Y5 | 689 | TOP1_STAAN DNA topoisomerase 1 OS=Staphylococ... | 503 | 4e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 28 | Q99UM1 | 689 | TOP1_STAAM DNA topoisomerase 1 OS=Staphylococ... | 503 | 4e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 29 | P55991 | 736 | TOP1_HELPY DNA topoisomerase 1 OS=pylori). GN... | 572 | 6e-26 | 117 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 30 | Q49X35 | 688 | TOP1_STAS1 DNA topoisomerase 1 OS=DSM 20229).... | 540 | 6e-26 | 117 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 31 | Q06AK7 | 689 | TOP1_STAAU DNA topoisomerase 1 OS=Staphylococ... | 503 | 6e-26 | 117 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. |