Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR234W
Length:
656
Number of sequences:
5887
Description:
YLR234W TOP3 SGDID:S000004224, Chr XII from 609783-611753, Genome Release 64-1-1, Verified ORF, "DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P13099    656   TOP3_YEAST DNA topoisomerase 3 OS=Saccharomyc...6560     1381     100     100GO:0005634; C:nucleus; IC:SGD.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IDA:SGD.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0000018; P:regulation of DNA recombination; IMP:SGD.::GO:0007004; P:telomere maintenance via telomerase; IMP:SGD.
2O60126    622   TOP3_SCHPO DNA topoisomerase 3 OS=Schizosacch...6560     541     44     61GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.::GO:0031422; C:RecQ helicase-Topo III complex; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0043007; P:maintenance of rDNA; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0045910; P:negative regulation of DNA recombination; TAS:PomBase.::GO:0007000; P:nucleolus organization; IMP:PomBase.::GO:0031297; P:replication fork processing; NAS:PomBase.::GO:0000712; P:resolution of meiotic recombination intermediates; TAS:PomBase.
3Q13472    1001   TOP3A_HUMAN DNA topoisomerase 3-alpha OS=Homo...6349e-147     458     42     58GO:0005694; C:chromosome; IEA:InterPro.::GO:0016605; C:PML body; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007126; P:meiosis; TAS:ProtInc.
4O70157    1003   TOP3A_MOUSE DNA topoisomerase 3-alpha OS=Mus ...6357e-146     456     41     59GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
5Q8T2T7    828   TOP3_DICDI DNA topoisomerase 3 OS=Dictyosteli...6521e-143     445     38     57GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
6O61660    759   TOP3_CAEEL DNA topoisomerase 3 OS=Caenorhabdi...6313e-141     437     40     57GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007276; P:gamete generation; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.
7Q9NG98    1250   TOP3A_DROME DNA topoisomerase 3-alpha OS=Dros...6398e-121     395     37     54GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:FlyBase.
8O95985    862   TOP3B_HUMAN DNA topoisomerase 3-beta-1 OS=Hom...6442e-96     322     34     48GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
9O96651    875   TOP3B_DROME DNA topoisomerase 3-beta OS=Droso...6372e-94     316     33     49GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0004520; F:endodeoxyribonuclease activity; IDA:FlyBase.
GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:FlyBase.::GO:0006265; P:DNA topological change; IEA:InterPro.
10Q9Z321    862   TOP3B_MOUSE DNA topoisomerase 3-beta-1 OS=Mus...6404e-94     315     33     49GO:0000793; C:condensed chromosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
GO:0007059; P:chromosome segregation; IMP:MGI.::GO:0006265; P:DNA topological change; IEA:InterPro.
11O28469    663   TOP1_ARCFU DNA topoisomerase 1 OS=9628 / NBRC...6309e-50     188     26     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
12Q9HM08    770   TOP1_THEAC DNA topoisomerase 1 OS=NBRC 15155 ...6255e-47     181     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
13Q59046    761   TOP1_METJA DNA topoisomerase 1 OS=JCM 10045 /...6391e-44     174     26     46GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
14Q9UYS8    685   TOP1_PYRAB DNA topoisomerase 1 OS=Pyrococcus ...6472e-44     172     25     45GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
15O58356    686   TOP1_PYRHO DNA topoisomerase 1 OS=NBRC 100139...6404e-44     171     24     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
16O27661    718   TOP1_METTH DNA topoisomerase 1 OS=thermoautot...5891e-41     164     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
17P43012    868   TOP1_HAEIN DNA topoisomerase 1 OS=Haemophilus...4842e-30     131     26     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
18Q9PLZ2    700   TOP1_CAMJE DNA topoisomerase 1 OS=Campylobact...4932e-27     121     25     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
19Q9CN30    868   TOP1_PASMU DNA topoisomerase 1 OS=Pasteurella...4796e-27     120     25     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
20Q5HGI2    689   TOP1_STAAC DNA topoisomerase 1 OS=Staphylococ...5032e-26     118     24     41GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
21Q2FZ32    689   TOP1_STAA8 DNA topoisomerase 1 OS=Staphylococ...5032e-26     118     24     41GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
22Q2FHI8    689   TOP1_STAA3 DNA topoisomerase 1 OS=Staphylococ...5032e-26     118     24     41GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
23Q2YXL8    689   TOP1_STAAB DNA topoisomerase 1 OS=Staphylococ...5033e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
24Q8NWZ9    689   TOP1_STAAW DNA topoisomerase 1 OS=Staphylococ...5034e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
25Q6G9W3    689   TOP1_STAAS DNA topoisomerase 1 OS=Staphylococ...5034e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
26Q6GHI5    689   TOP1_STAAR DNA topoisomerase 1 OS=Staphylococ...5034e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
27Q7A5Y5    689   TOP1_STAAN DNA topoisomerase 1 OS=Staphylococ...5034e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
28Q99UM1    689   TOP1_STAAM DNA topoisomerase 1 OS=Staphylococ...5034e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
29P55991    736   TOP1_HELPY DNA topoisomerase 1 OS=pylori). GN...5726e-26     117     24     41GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
30Q49X35    688   TOP1_STAS1 DNA topoisomerase 1 OS=DSM 20229)....5406e-26     117     24     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
31Q06AK7    689   TOP1_STAAU DNA topoisomerase 1 OS=Staphylococ...5036e-26     117     23     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
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