| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations | 
					61 | Q87AQ6 | 815 | TOP1_XYLFT DNA topoisomerase 1 OS=Xylella fas... | 519 | 1e-20 | 100 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 62 | P46799 | 633 | TOP1_THEMA DNA topoisomerase 1 OS=Thermotoga ... | 559 | 3e-20 | 99 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 63 | P0A620 | 934 | TOP1_MYCTU DNA topoisomerase 1 OS=Mycobacteri... | 607 | 5e-18 | 92.4 | 23 | 37 | GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE. | 64 | P0A621 | 934 | TOP1_MYCBO DNA topoisomerase 1 OS=Mycobacteri... | 607 | 5e-18 | 92.4 | 23 | 37 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 65 | P43704 | 651 | TOP3_HAEIN DNA topoisomerase 3 OS=Haemophilus... | 599 | 5e-18 | 91.7 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 66 | P96583 | 727 | TOP3_BACSU DNA topoisomerase 3 OS=Bacillus su... | 682 | 5e-18 | 91.7 | 22 | 39 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 67 | P40687 | 649 | TOP3_SALTY DNA topoisomerase 3 OS=Salmonella ... | 564 | 8e-18 | 91.3 | 25 | 39 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 68 | P14294 | 653 | TOP3_ECOLI DNA topoisomerase 3 OS=Escherichia... | 561 | 2e-17 | 89.7 | 24 | 39 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IDA:EcoliWiki. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 69 | O73954 | 1060 | TOP1_PYRFU DNA topoisomerase 1 OS=Pyrococcus ... | 288 | 9e-16 | 85.1 | 24 | 47 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW. | 70 | Q8Z6F5 | 649 | TOP3_SALTI DNA topoisomerase 3 OS=Salmonella ... | 564 | 5e-17 | 88.6 | 25 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 71 | Q9JN65 | 719 | TOP1_MYCGA DNA topoisomerase 1 OS=Mycoplasma ... | 558 | 2e-16 | 86.7 | 22 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 72 | Q9KQF5 | 647 | TOP3_VIBCH DNA topoisomerase 3 OS=Vibrio chol... | 397 | 8e-16 | 84.7 | 25 | 42 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 73 | O29238 | 1054 | RGYR_ARCFU Reverse gyrase OS=9628 / NBRC 1001... | 532 | 0.000000000000003 | 83.6 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 74 | Q9YC75 | 1215 | RGYR2_AERPE Reverse gyrase 2 OS=100138 / K1).... | 601 | 0.000000000000004 | 83.2 | 23 | 39 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 75 | O83409 | 731 | TOP1_TREPA DNA topoisomerase 1 OS=Treponema p... | 492 | 0.00000000000001 | 81.3 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 76 | Q73E74 | 729 | TOP3_BACC1 DNA topoisomerase 3 OS=Bacillus ce... | 698 | 0.00000000000001 | 80.9 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 77 | Q81IH1 | 729 | TOP3_BACCR DNA topoisomerase 3 OS=Bacillus ce... | 701 | 0.00000000000002 | 80.9 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 78 | Q5WAX6 | 729 | TOP3_BACSK DNA topoisomerase 3 OS=Bacillus cl... | 442 | 0.00000000000002 | 80.5 | 26 | 41 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 79 | Q63GK5 | 729 | TOP3_BACCZ DNA topoisomerase 3 OS=Bacillus ce... | 698 | 0.00000000000003 | 79.7 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 80 | Q6HP19 | 729 | TOP3_BACHK DNA topoisomerase 3 OS=Bacillus th... | 698 | 0.00000000000004 | 79.7 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 81 | Q81Z97 | 729 | TOP3_BACAN DNA topoisomerase 3 OS=Bacillus an... | 698 | 0.00000000000004 | 79.7 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 82 | A0R979 | 729 | TOP3_BACAH DNA topoisomerase 3 OS=Bacillus th... | 698 | 0.00000000000004 | 79.7 | 22 | 38 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 83 | Q9CP53 | 650 | TOP3_PASMU DNA topoisomerase 3 OS=Pasteurella... | 515 | 0.00000000000005 | 79.3 | 24 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 84 | O34204 | 699 | TOP1_FERIS DNA topoisomerase 1 OS=Fervidobact... | 536 | 0.00000000000006 | 79 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 85 | O67226 | 1159 | RGYR2_AQUAE Reverse gyrase 2 OS=Aquifex aeoli... | 552 | 0.0000000000001 | 78.6 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 86 | O67037 | 1146 | RGYR1_AQUAE Reverse gyrase 1 OS=Aquifex aeoli... | 630 | 0.0000000000002 | 77.4 | 22 | 37 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 87 | P40114 | 870 | TOP1_BACAN DNA topoisomerase 1 OS=Bacillus an... | 597 | 0.0000000000003 | 77 | 22 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 88 | Q6GEH9 | 711 | TOP3_STAAR DNA topoisomerase 3 OS=Staphylococ... | 480 | 0.0000000000003 | 76.6 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 89 | P0C2W6 | 711 | TOP3_STAAB Putative DNA topoisomerase 3 OS=St... | 480 | 0.0000000000003 | 76.6 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 90 | Q7A075 | 711 | TOP3_STAAW DNA topoisomerase 3 OS=Staphylococ... | 480 | 0.0000000000004 | 76.3 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 91 | Q6G767 | 711 | TOP3_STAAS DNA topoisomerase 3 OS=Staphylococ... | 480 | 0.0000000000004 | 76.3 | 23 | 40 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. |