Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR231C
Length:
453
Number of sequences:
5887
Description:
YLR231C BNA5 SGDID:S000004221, Chr XII from 607119-605758, Genome Release 64-1-1, reverse complement, Verified ORF, "Kynureninase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q05979    453   KYNU_YEAST Kynureninase OS=Saccharomyces cere...4530     942     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0030429; F:kynureninase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
2Q6BI19    460   KYNU_DEBHA Kynureninase OS=0083 / IGC 2968) (...4600     549     60     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
3A7TR79    455   KYNU_VANPO Kynureninase OS=(Kluyveromyces pol...4300     536     60     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
4A3LQD7    465   KYNU_PICST Kynureninase OS=NRRL Y-11545) (Yea...4620     532     57     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
5Q59QC4    461   KYNU_CANAL Kynureninase OS=Candida albicans (...4606e-179     516     56     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
6A5DM91    445   KYNU_PICGU Kynureninase OS=1539 / NBRC 10279 ...4545e-176     508     56     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
7Q750P5    447   KYNU_ASHGO Kynureninase OS=Y-1056) (Yeast) (E...4557e-173     499     54     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
8A5DTF4    461   KYNU_LODEL Kynureninase OS=NBRC 1676 / NRRL Y...4592e-162     473     54     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
9Q6CDM0    437   KYNU_YARLI Kynureninase OS=lipolytica). GN=BN...4481e-149     440     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
10A9V3C0    460   KYNU_MONBE Kynureninase OS=Monosiga brevicoll...4536e-124     375     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
11Q7RXY2    472   KYNU1_NEUCR Kynureninase 1 OS=1257 / FGSC 987...4592e-122     372     45     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
12Q0CPB0    483   KYNU1_ASPTN Kynureninase 1 OS=Aspergillus ter...4695e-121     369     46     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
13A1C688    486   KYNU1_ASPCL Kynureninase 1 OS=3887 / NRRL 1)....4711e-120     367     46     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
14Q2U038    487   KYNU1_ASPOR Kynureninase 1 OS=Aspergillus ory...4573e-120     367     45     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
15P0CO53    453   KYNU_CRYNB Kynureninase OS=(Filobasidiella ne...4323e-118     360     45     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
16P0CO52    453   KYNU_CRYNJ Kynureninase OS=ATCC MYA-565) (Fil...4321e-117     359     45     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
17Q54Q04    451   KYNU_DICDI Kynureninase OS=Dictyostelium disc...4464e-116     355     45     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
18Q1DZA6    480   KYNU_COCIM Kynureninase OS=Coccidioides immit...4755e-116     355     44     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
19A7SCH8    465   KYNU_NEMVE Kynureninase OS=Nematostella vecte...4661e-115     354     43     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
20Q1DDU5    426   KYNU_MYXXD Kynureninase OS=Myxococcus xanthus...4451e-115     352     44     59GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
21Q2UJE8    468   KYNU2_ASPOR Kynureninase 2 OS=Aspergillus ory...4652e-115     353     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
22A1DGW4    487   KYNU1_NEOFI Kynureninase 1 OS=181) (Aspergill...4696e-115     353     45     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
23Q5B0H8    487   KYNU1_EMENI Kynureninase 1 OS=194 / M139) (As...4696e-115     353     44     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
24A2R7T0    472   KYNU1_ASPNC Kynureninase 1 OS=Aspergillus nig...4558e-115     352     46     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
25Q9CXF0    464   KYNU_MOUSE Kynureninase OS=Mus musculus (Mous...4561e-114     352     45     59GO:0005739; C:mitochondrion; IDA:MGI.
GO:0030429; F:kynureninase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
26Q4X1D4    509   KYNU1_ASPFU Kynureninase 1 OS=A1100) (Aspergi...4911e-114     353     44     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
27B0XS72    509   KYNU1_ASPFC Kynureninase 1 OS=(Aspergillus fu...4911e-114     353     44     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
28A6RSP5    475   KYNU_BOTFB Kynureninase OS=cinerea). GN=bna5 ...4646e-113     347     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
29Q16719    465   KYNU_HUMAN Kynureninase OS=Homo sapiens (Huma...4541e-111     343     45     60GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0030429; F:kynureninase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0043420; P:anthranilate metabolic process; IDA:UniProtKB.::GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0019805; P:quinolinate biosynthetic process; IDA:UniProtKB.::GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.::GO:0034516; P:response to vitamin B6; IMP:UniProtKB.
30A7ESB8    475   KYNU_SCLS1 Kynureninase OS=mold) (Whetzelinia...4643e-111     343     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030429; F:kynureninase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
31P70712    464   KYNU_RAT Kynureninase OS=Rattus norvegicus (R...4557e-111     342     44     58GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0030429; F:kynureninase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IDA:RGD.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0019442; P:tryptophan catabolic process to acetyl-CoA; IDA:RGD.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD.
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