Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR229C
Length:
191
Number of sequences:
5887
Description:
YLR229C CDC42 SGDID:S000004219, Chr XII from 604787-604212, Genome Release 64-1-1, reverse complement, Verified ORF, "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721Q96AH8    199   RAB7B_HUMAN Ras-related protein Rab-7b OS=Hom...1260.000000002     57.8     32     48GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
722P63033    266   RHES_RAT GTP-binding protein Rhes OS=Rattus n...930.000000002     58.9     32     54GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
723P63032    266   RHES_MOUSE GTP-binding protein Rhes OS=Mus mu...930.000000002     58.9     32     54GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007626; P:locomotory behavior; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:UniProtKB.
724Q8WUD1    216   RAB2B_HUMAN Ras-related protein Rab-2B OS=Hom...1680.000000002     58.2     24     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
725Q9FE79    223   RAA4C_ARATH Ras-related protein RABA4c OS=Ara...1180.000000002     58.2     27     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
726C4YKT4    288   RAS1_CANAW Ras-like protein 1 OS=Candida albi...1560.000000002     58.9     28     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
727P0CY32    290   RAS1_CANAX Ras-like protein 1 OS=Candida albi...1560.000000002     58.9     28     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
728Q5R8Z8    215   RAB14_PONAB Ras-related protein Rab-14 OS=Pon...1710.000000002     57.8     23     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
729Q91V41    215   RAB14_MOUSE Ras-related protein Rab-14 OS=Mus...1710.000000002     57.8     23     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006895; P:Golgi to endosome transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
730P61106    215   RAB14_HUMAN Ras-related protein Rab-14 OS=Hom...1710.000000002     57.8     23     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; ISS:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; ISS:UniProtKB.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
731Q5ZKU5    215   RAB14_CHICK Ras-related protein Rab-14 OS=Gal...1710.000000002     57.8     23     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
732Q41640    206   RAB7_VIGAC Ras-related protein Rab7 OS=Vigna ...1330.000000002     57.8     29     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
733P61107    215   RAB14_RAT Ras-related protein Rab-14 OS=Rattu...1710.000000002     57.8     23     46GO:0097208; C:alveolar lamellar body; IDA:RGD.::GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:UniProtKB.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0045176; P:apical protein localization; IDA:RGD.::GO:0007589; P:body fluid secretion; IMP:RGD.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032880; P:regulation of protein localization; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
734Q52NJ6    215   RAB14_PIG Ras-related protein Rab-14 OS=Sus s...1710.000000002     57.8     23     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
735P10833    218   RRAS_MOUSE Ras-related protein R-Ras OS=Mus m...1620.000000002     57.8     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
736Q29RR0    256   RAB26_BOVIN Ras-related protein Rab-26 OS=Bos...1640.000000002     58.2     26     47GO:0031226; C:intrinsic to plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0035272; P:exocrine system development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
737P38544    215   RAN_ONCVO GTP-binding nuclear protein Ran OS=...1360.000000003     57.4     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
738Q59XU5    291   RAS1_CANAL Ras-like protein 1 OS=Candida albi...1070.000000003     58.5     32     51GO:0005886; C:plasma membrane; IDA:CGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:CGD.
GO:0044413; P:avoidance of host defenses; IMP:CGD.::GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0034605; P:cellular response to heat; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:CGD.::GO:0045595; P:regulation of cell differentiation; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
739Q75J93    842   CPAS1_DICDI Circularly permutated Ras protein...1220.000000003     59.3     32     50GO:0030127; C:COPII vesicle coat; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
740Q5R573    229   RBL2A_PONAB Rab-like protein 2A OS=Pongo abel...1170.000000003     57.8     27     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
741Q40191    226   RB11A_LOTJA Ras-related protein Rab11A OS=Lot...1680.000000003     57.4     23     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
742Q8VHP8    278   RB40B_MOUSE Ras-related protein Rab-40B OS=Mu...1700.000000003     58.2     29     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
743Q8MYF2    256   RABJ_DICDI Ras-related protein RabJ OS=Dictyo...1690.000000003     57.8     28     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
744Q8TFK3    214   GSP1_YARLI GTP-binding nuclear protein GSP1/R...1350.000000004     57.4     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
745Q9FJN8    226   RAA4A_ARATH Ras-related protein RABA4a OS=Ara...1680.000000004     57.4     24     46GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
746A5WW21    663   RASEF_DANRE Ras and EF-hand domain-containing...1570.000000004     58.9     27     47GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
747P59279    216   RAB2B_MOUSE Ras-related protein Rab-2B OS=Mus...1600.000000004     57     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
748P61018    213   RAB4B_HUMAN Ras-related protein Rab-4B OS=Hom...1680.000000004     57     25     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
749P61017    213   RAB4B_CANFA Ras-related protein Rab-4B OS=Can...1680.000000004     57     25     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
750Q12829    278   RB40B_HUMAN Ras-related protein Rab-40B OS=Ho...1700.000000005     57.8     29     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
751Q6IMK3    273   DJC27_DANRE DnaJ homolog subfamily C member 2...1740.000000005     57.8     24     45
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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