Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR229C
Length:
191
Number of sequences:
5887
Description:
YLR229C CDC42 SGDID:S000004219, Chr XII from 604787-604212, Genome Release 64-1-1, reverse complement, Verified ORF, "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511P01116    189   RASK_HUMAN GTPase KRas OS=Homo sapiens (Human...1630.000000000002     65.9     28     47GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
512P05774    183   RAS_CARAU Ras-like protein OS=Carassius aurat...1630.000000000002     65.9     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
513P38555    223   YPT31_YEAST GTP-binding protein YPT31/YPT8 OS...1720.000000000002     66.2     27     45GO:0005768; C:endosome; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0034498; P:early endosome to Golgi transport; IGI:SGD.::GO:0006887; P:exocytosis; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
514Q96HU8    199   DIRA2_HUMAN GTP-binding protein Di-Ras2 OS=Ho...1710.000000000003     65.9     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
515P49104    210   RAB2B_MAIZE Ras-related protein Rab-2-B OS=Ze...1680.000000000003     65.9     24     47GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
516Q54RX9    214   RAB5B_DICDI Putative ras-related protein Rab-...1710.000000000003     65.9     27     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
517Q9LS94    206   RAG3F_ARATH Ras-related protein RABG3f OS=Ara...1320.000000000003     65.9     31     52GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
518P35281    200   RAB10_RAT Ras-related protein Rab-10 OS=Rattu...1680.000000000003     65.9     24     49GO:0005624; C:membrane fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
519Q95KD9    199   DIRA2_MACFA GTP-binding protein Di-Ras2 OS=Ma...1710.000000000003     65.9     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
520P51539    194   RAS1_HYDVU Ras-like protein RAS1 OS=Hydra vul...1550.000000000003     65.5     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
521Q5R6S2    199   DIRA2_PONAB GTP-binding protein Di-Ras2 OS=Po...1710.000000000003     65.5     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
522Q5JT25    222   RAB41_HUMAN Ras-related protein Rab-41 OS=Hom...1750.000000000003     65.9     30     49
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
523P08645    184   RAS3_DROME Ras-like protein 3 OS=Drosophila m...1700.000000000003     65.5     25     49GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IGI:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; TAS:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006930; P:substrate-dependent cell migration, cell extension; IMP:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
524O95755    333   RAB36_HUMAN Ras-related protein Rab-36 OS=Hom...1860.000000000003     67     29     43GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
525P51996    222   YPT32_YEAST GTP-binding protein YPT32/YPT11 O...1770.000000000003     65.9     26     45GO:0005768; C:endosome; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0034498; P:early endosome to Golgi transport; IGI:SGD.::GO:0006887; P:exocytosis; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
526Q96A58    199   RERG_HUMAN Ras-related and estrogen-regulated...1630.000000000003     65.5     29     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IDA:HPA.
GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.::GO:0019003; F:GDP binding; TAS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
527P49103    209   RAB2A_MAIZE Ras-related protein Rab-2-A OS=Ze...1680.000000000004     65.5     24     47GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
528O17915    215   RAN_CAEEL GTP-binding nuclear protein ran-1 O...1360.000000000004     65.5     27     49GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0046785; P:microtubule polymerization; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
529Q9SF92    205   RAC2B_ARATH Ras-related protein RABC2b OS=Ara...1830.000000000004     65.5     25     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
530E2RQ15    213   RAB25_CANFA Ras-related protein Rab-25 OS=Can...1690.000000000004     65.5     27     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0031260; C:pseudopodium membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
531P15064    189   RASG_DICDI Ras-like protein rasG OS=Dictyoste...1720.000000000004     65.1     32     47GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IGI:dictyBase.::GO:0032861; P:activation of Rap GTPase activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0008283; P:cell proliferation; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IMP:dictyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:dictyBase.::GO:0030828; P:positive regulation of cGMP biosynthetic process; IMP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0050927; P:positive regulation of positive chemotaxis; IMP:dictyBase.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0046586; P:regulation of calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0001932; P:regulation of protein phosphorylation; IMP:dictyBase.
532Q54DA7    205   RAB4_DICDI Ras-related protein Rab-4 OS=Dicty...1680.000000000004     65.5     26     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
533Q06AU7    201   RAB1B_PIG Ras-related protein Rab-1B OS=Sus s...1240.000000000004     65.5     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
534Q9XI98    206   RAG3E_ARATH Ras-related protein RABG3e OS=Ara...1350.000000000004     65.5     32     50GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
535P51152    208   RAB12_CANFA Ras-related protein Rab-12 OS=Can...1680.000000000004     65.5     24     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
536Q13636    194   RAB31_HUMAN Ras-related protein Rab-31 OS=Hom...1230.000000000005     65.1     28     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
537Q58DW6    213   RAB25_BOVIN Ras-related protein Rab-25 OS=Bos...1880.000000000005     65.1     26     46GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0031260; C:pseudopodium membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
538Q55FK2    208   RAB6_DICDI Ras-related protein Rab-6 OS=Dicty...1830.000000000005     65.1     28     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
539P92963    211   RAB1C_ARATH Ras-related protein RABB1c OS=Ara...1680.000000000005     65.1     24     48GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
540O42785    214   RASL_COLTR Ras-like protein OS=Colletotrichum...1580.000000000005     65.1     30     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
541Q8R367    199   RERG_MOUSE Ras-related and estrogen-regulated...1710.000000000005     65.1     30     47GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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