Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR229C
Length:
191
Number of sequences:
5887
Description:
YLR229C CDC42 SGDID:S000004219, Chr XII from 604787-604212, Genome Release 64-1-1, reverse complement, Verified ORF, "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P60763    192   RAC3_HUMAN Ras-related C3 botulinum toxin sub...1772e-92     275     71     84GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0031941; C:filamentous actin; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0030031; P:cell projection assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
32O88931    192   RAC2_CAVPO Ras-related C3 botulinum toxin sub...1922e-92     274     66     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
33P34144    194   RAC1A_DICDI Rho-related protein rac1A OS=Dict...1942e-91     272     65     79GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
34Q24814    196   RACA_ENTHI Rho-related protein racA OS=Entamo...1882e-90     270     65     82GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
35P34146    193   RAC1C_DICDI Rho-related protein rac1C OS=Dict...1932e-89     267     64     79GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
36P34145    194   RAC1B_DICDI Rho-related protein rac1B OS=Dict...1947e-89     265     62     79GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; TAS:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006897; P:endocytosis; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0008360; P:regulation of cell shape; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
37P34148    195   RACB_DICDI Rho-related protein racB OS=Dictyo...1952e-87     261     62     79GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0030041; P:actin filament polymerization; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
38O94103    190   CDC42_COLGL Cell division control protein 42 ...1923e-84     253     69     78GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
39Q94124    195   RAC2_CAEEL Ras-related protein rac-2 OS=Caeno...1958e-84     253     59     75GO:0030424; C:axon; IDA:WormBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:WormBase.
GO:0005525; F:GTP binding; IDA:WormBase.::GO:0003924; F:GTPase activity; IDA:WormBase.
GO:0048846; P:axon extension involved in axon guidance; IGI:WormBase.::GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0008045; P:motor axon guidance; IGI:WormBase.::GO:0001764; P:neuron migration; IGI:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
40P17081    205   RHOQ_HUMAN Rho-related GTP-binding protein Rh...1762e-83     252     66     81GO:0005884; C:actin filament; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0032427; F:GBD domain binding; IPI:BHF-UCL.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005522; F:profilin binding; IPI:BHF-UCL.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IC:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
41Q9JJL4    205   RHOQ_RAT Rho-related GTP-binding protein RhoQ...1763e-83     251     66     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
42Q8R527    205   RHOQ_MOUSE Rho-related GTP-binding protein Rh...1763e-83     251     66     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IDA:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IC:BHF-UCL.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
43P34149    192   RACC_DICDI Rho-related protein racC OS=Dictyo...1901e-80     244     59     77GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0016477; P:cell migration; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0045184; P:establishment of protein localization; IMP:dictyBase.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
44O96390    193   RACF1_DICDI Rho-related protein racF1 OS=Dict...1792e-80     244     62     80GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
45P84096    191   RHOG_MOUSE Rho-related GTP-binding protein Rh...1913e-80     243     59     74GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.
46P84095    191   RHOG_HUMAN Rho-related GTP-binding protein Rh...1913e-80     243     59     74GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
47P84097    191   RHOG_CRICR Rho-related GTP-binding protein Rh...1913e-80     243     59     74GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
48Q24815    163   RACB_ENTHI Rho-related protein racB OS=Entamo...1636e-80     241     65     80GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
49Q9GPS3    193   RACF2_DICDI Rho-related protein racF2 OS=Dict...1771e-79     242     62     81GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0016337; P:cell-cell adhesion; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
50O76321    199   RECG_ENTHI Rho-related protein racG OS=Entamo...1773e-78     239     62     80GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
51Q9H4E5    214   RHOJ_HUMAN Rho-related GTP-binding protein Rh...1886e-77     236     59     78GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
52Q9ER71    214   RHOJ_MOUSE Rho-related GTP-binding protein Rh...1784e-75     231     60     79GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
53Q24817    198   RACD_ENTHI Rho-related protein racD OS=Entamo...1727e-74     228     60     78GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
54Q24816    194   RACC_ENTHI Rho-related protein racC OS=Entamo...1895e-70     218     55     71GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
55Q6Z7L8    197   RAC7_ORYSJ Rac-like GTP-binding protein 7 OS=...1935e-70     218     54     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
56Q38912    198   RAC3_ARATH Rac-like GTP-binding protein ARAC3...1772e-69     216     57     73GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030427; C:site of polarized growth; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
57Q6Z808    214   RAC3_ORYSJ Rac-like GTP-binding protein 3 OS=...1814e-68     213     52     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
58Q38903    201   RAC2_ARATH Rac-like GTP-binding protein ARAC2...1754e-68     213     56     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
59Q9EQT3    261   RHOU_MOUSE Rho-related GTP-binding protein Rh...1757e-68     214     55     75GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IMP:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.
60Q67VP4    215   RAC4_ORYSJ Rac-like GTP-binding protein 4 OS=...1772e-67     211     55     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
61P92978    197   RAC11_ARATH Rac-like GTP-binding protein ARAC...1743e-67     211     57     72GO:0045177; C:apical part of cell; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0005886; C:plasma membrane; TAS:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0032794; F:GTPase activating protein binding; IPI:TAIR.
GO:0051650; P:establishment of vesicle localization; IDA:TAIR.::GO:0009860; P:pollen tube growth; IMP:TAIR.::GO:0030834; P:regulation of actin filament depolymerization; IGI:TAIR.::GO:0030833; P:regulation of actin filament polymerization; IGI:TAIR.::GO:0017157; P:regulation of exocytosis; IDA:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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