Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR228C
Length:
814
Number of sequences:
5887
Description:
YLR228C ECM22 SGDID:S000004218, Chr XII from 602463-600019, Genome Release 64-1-1, reverse complement, Verified ORF, "Sterol regulatory element binding protein, regulates transcription of sterol biosynthetic genes; contains Zn[2]-Cys[6] binuclear cluster; homologous to Upc2p; relocates from intracellular membranes to perinuclear foci on sterol depletion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q05958    814   ECM22_YEAST Sterol regulatory element-binding...8140     1677     100     100GO:0016020; C:membrane; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035961; P:positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0035969; P:positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.
2Q12151    913   UPC2_YEAST Sterol uptake control protein 2 OS...862e-31     135     67     79GO:0016020; C:membrane; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071456; P:cellular response to hypoxia; IMP:SGD.::GO:0035961; P:positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0035969; P:positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
3P40971    790   LYS14_YEAST Lysine biosynthesis regulatory pr...1460.00000004     60.5     29     47GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.::GO:2001196; P:positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
4Q9P326    696   PRO1_NEUCR Transcriptional regulatory protein...410.0000007     56.6     49     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
5Q9UT46    508   MOC3_SCHPO Transcriptional regulatory protein...330.000001     55.8     58     73GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0071277; P:cellular response to calcium ion; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IMP:PomBase.
6O74308    419   YOG2_SCHPO Uncharacterized transcriptional re...390.000003     53.9     49     64GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IMP:PomBase.
7P39001    836   UME6_YEAST Transcriptional regulatory protein...530.00004     50.8     43     55GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.
GO:0070491; F:repressing transcription factor binding; IDA:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0034389; P:lipid particle organization; IMP:SGD.::GO:0010674; P:negative regulation of transcription from RNA polymerase II promoter during meiosis; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0001081; P:nitrogen catabolite repression of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006659; P:phosphatidylserine biosynthetic process; IMP:SGD.::GO:0045836; P:positive regulation of meiosis; IMP:SGD.::GO:0010673; P:positive regulation of transcription from RNA polymerase II promoter during meiosis; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0009847; P:spore germination; IMP:SGD.
8Q1MTM9    977   YFN1_SCHPO Uncharacterized transcriptional re...1430.0001     49.7     25     43GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
9O59744    815   YN28_SCHPO Uncharacterized transcriptional re...540.0001     49.7     41     57GO:0000785; C:chromatin; NAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
10P07272    904   PPR1_YEAST Pyrimidine pathway regulatory prot...1480.0002     48.5     28     45GO:0005634; C:nucleus; IC:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IDA:SGD.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
11Q9HFR4    1862   ATG2_PICPA Autophagy-related protein 2 OS=Pic...350.0002     48.9     46     63GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
12P08657    865   LAC9_KLULA Lactose regulatory protein LAC9 OS...330.0003     48.1     45     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
13P53338    473   MAL13_YEAST Maltose fermentation regulatory p...520.0003     47.8     42     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000023; P:maltose metabolic process; IEA:UniProtKB-KW.
14Q9HDX1    697   YKN4_SCHPO Uncharacterized transcriptional re...580.0004     47.8     33     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
15Q6CXS0    657   OAF3_KLULA Oleate activated transcription fac...310.0004     47.4     55     65GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
16Q06149    701   PDR8_YEAST Transcription factor PDR8 OS=Sacch...530.0006     47.4     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IPI:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD.
17O60130    827   YH7G_SCHPO Putative transcriptional regulator...680.0006     47     29     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
18P28875    388   CZF1_CANAW Zinc finger protein 1 OS=Candida a...350.001     45.8     37     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
19Q10086    637   YAO7_SCHPO Uncharacterized transcriptional re...390.001     46.2     41     62GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
20P38157    468   MAL33_YEAST Maltose fermentation regulatory p...440.001     45.8     45     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000023; P:maltose metabolic process; IEA:UniProtKB-KW.
21O13658    738   YBCB_SCHPO Uncharacterized transcriptional re...1510.001     46.2     30     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22P10508    473   MAL63_YEASX Maltose fermentation regulatory p...520.001     45.8     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000023; P:maltose metabolic process; IEA:UniProtKB-KW.
23P26370    528   UGA3_YEAST Transcriptional activator protein ...610.001     45.8     36     46GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009450; P:gamma-aminobutyric acid catabolic process; IMP:SGD.::GO:0001080; P:nitrogen catabolite activation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0019740; P:nitrogen utilization; IMP:SGD.
24P28348    892   NIRA_EMENI Nitrogen assimilation transcriptio...910.002     45.8     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
25O59741    743   YN25_SCHPO Uncharacterized transcriptional re...390.002     45.8     36     67GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26O14130    783   YF54_SCHPO Uncharacterized transcriptional re...470.002     45.4     40     55GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q06595    470   YP196_YEAST Maltose fermentation regulatory p...420.004     44.3     43     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
28A7TGQ2    802   OAF3_VANPO Oleate activated transcription fac...560.005     44.3     39     54GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
29P52960    996   PIP2_YEAST Peroxisome proliferation transcrip...430.006     43.9     37     58GO:0005634; C:nucleus; IPI:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071400; P:cellular response to oleic acid; IPI:SGD.::GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:SGD.
30P35995    705   YKW2_YEAST Uncharacterized transcriptional re...990.008     43.5     24     46GO:0072686; C:mitotic spindle; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
31P10563    825   QUTA_EMENI Quinic acid utilization activator ...760.008     43.5     25     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019630; P:quinate metabolic process; IEA:UniProtKB-KW.
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