Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR214W
Length:
686
Number of sequences:
5887
Description:
YLR214W FRE1 SGDID:S000004204, Chr XII from 568567-570627, Genome Release 64-1-1, Verified ORF, "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32791    686   FRE1_YEAST Ferric/cupric reductase transmembr...6860     1427     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0015677; P:copper ion import; IDA:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006826; P:iron ion transport; IDA:SGD.
2P78588    669   FREL_CANAX Probable ferric reductase transmem...5691e-67     240     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
3P36033    711   FRE2_YEAST Ferric/cupric reductase transmembr...6993e-51     193     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0015677; P:copper ion import; IDA:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006826; P:iron ion transport; IDA:SGD.
4Q08905    711   FRE3_YEAST Ferric reductase transmembrane com...6681e-49     189     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015891; P:siderophore transport; IMP:SGD.
5Q08908    694   FRE5_YEAST Ferric reductase transmembrane com...6891e-48     185     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
6P53746    719   FRE4_YEAST Ferric reductase transmembrane com...6822e-38     155     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IMP:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IMP:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015891; P:siderophore transport; IMP:SGD.
7Q12473    712   FRE6_YEAST Ferric reductase transmembrane com...5474e-30     130     23     43GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IMP:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0015677; P:copper ion import; IGI:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006880; P:intracellular sequestering of iron ion; IMP:SGD.
8O94727    564   FRP2_SCHPO Ferric/cupric reductase transmembr...4791e-18     93.6     23     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:PomBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; ISS:PomBase.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0015677; P:copper ion import; ISS:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0034755; P:iron ion transmembrane transport; ISS:PomBase.::GO:0015891; P:siderophore transport; ISS:PomBase.
9Q12333    620   FRE7_YEAST Ferric/cupric reductase transmembr...5252e-18     93.2     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
10A6ZN61    620   FRE7_YEAS7 Ferric/cupric reductase transmembr...5252e-17     90.1     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
11Q04800    564   FRP1_SCHPO Ferric reductase transmembrane com...4762e-17     89.7     24     40GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:PomBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; TAS:PomBase.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0015677; P:copper ion import; ISS:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0033215; P:iron assimilation by reduction and transport; IMP:PomBase.::GO:0034755; P:iron ion transmembrane transport; IMP:PomBase.
12A3LN69    524   AIM14_PICST Probable metalloreductase AIM14 O...3990.0000000001     68.2     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
13Q9XYS3    517   NOXA_DICDI Superoxide-generating NADPH oxidas...3580.0000008     55.8     23     41GO:0043020; C:NADPH oxidase complex; ISS:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:dictyBase.::GO:0020037; F:heme binding; ISS:dictyBase.::GO:0050661; F:NADP binding; ISS:dictyBase.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IGI:dictyBase.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0042554; P:superoxide anion generation; ISS:dictyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
14Q95L74    570   CY24B_BISBI Cytochrome b-245 heavy chain OS=B...3970.000008     52.8     22     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
15Q6C188    525   AIM14_YARLI Probable metalloreductase AIM14 O...4100.000009     52.4     21     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
16O46522    570   CY24B_BOVIN Cytochrome b-245 heavy chain OS=B...3970.000009     52.4     22     37
GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
17Q9FLW2    707   FRO5_ARATH Ferric reduction oxidase 5 OS=Arab...3700.00001     52.4     21     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
18P53109    570   AIM14_YEAST Probable metalloreductase AIM14 O...3950.00001     52.4     22     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
19Q61093    570   CY24B_MOUSE Cytochrome b-245 heavy chain OS=M...3960.00003     50.8     23     38GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.
20A6ZU25    570   AIM14_YEAS7 Probable metalloreductase AIM14 O...3950.00004     50.4     22     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
21B3LHL3    570   AIM14_YEAS1 Probable metalloreductase AIM14 O...3950.00004     50.4     22     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
22C7GPP6    570   AIM14_YEAS2 Probable metalloreductase AIM14 O...3950.00004     50.4     22     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
23C5E4F2    526   AIM14_ZYGRC Probable metalloreductase AIM14 O...3480.00005     50.1     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
24Q8W110    699   FRO4_ARATH Ferric reduction oxidase 4 OS=Arab...3010.00007     49.7     21     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
25Q8VY13    728   FRO8_ARATH Ferric reduction oxidase 8, mitoch...3310.0001     49.3     21     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
26C8Z891    576   AIM14_YEAS8 Probable metalloreductase AIM14 O...3950.0001     49.3     22     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
27P04839    570   CY24B_HUMAN Cytochrome b-245 heavy chain OS=H...3960.0002     48.5     22     38GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL.::GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IMP:BHF-UCL.::GO:0020037; F:heme binding; IMP:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0016175; F:superoxide-generating NADPH oxidase activity; TAS:BHF-UCL.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0045087; P:innate immune response; IMP:BHF-UCL.::GO:0045730; P:respiratory burst; IMP:BHF-UCL.::GO:0042554; P:superoxide anion generation; IDA:BHF-UCL.
28Q8HZK2    1545   DUOX2_PIG Dual oxidase 2 OS=Sus scrofa (Pig)....3300.0004     47.8     22     43GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IEA:EC.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
GO:0042335; P:cuticle development; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.::GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; ISS:UniProtKB.
29Q8CIZ9    591   NOX1_MOUSE NADPH oxidase 1 OS=Mus musculus (M...2130.0006     46.6     24     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005768; C:endosome; IMP:MGI.::GO:0071438; C:invadopodium membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0072592; P:oxygen metabolic process; IMP:MGI.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IMP:MGI.::GO:0042554; P:superoxide anion generation; IDA:MGI.
30O81210    905   RBOHC_ARATH Respiratory burst oxidase homolog...3230.0006     46.6     20     37GO:0005887; C:integral to plasma membrane; IDA:TAIR.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IMP:TAIR.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
GO:0009060; P:aerobic respiration; IMP:TAIR.::GO:0033198; P:response to ATP; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IMP:TAIR.
31P92949    725   FRO2_ARATH Ferric reduction oxidase 2 OS=Arab...3510.0009     46.2     21     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015688; P:iron chelate transport; IMP:TAIR.::GO:0055072; P:iron ion homeostasis; IMP:TAIR.::GO:0009617; P:response to bacterium; IEP:TAIR.
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