Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR210W
Length:
460
Number of sequences:
5887
Description:
YLR210W CLB4 SGDID:S000004200, Chr XII from 562008-563390, Genome Release 64-1-1, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P0C242    352   CCNO_MOUSE Cyclin-O OS=Mus musculus (Mouse). ...2033e-16     83.2     28     48
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
122Q5E9K7    404   CCNE2_BOVIN G1/S-specific cyclin-E2 OS=Bos ta...2560.000000000000005     80.5     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
123Q8MUK3    518   CCNE_CAEBR G1/S-specific cyclin-E OS=Caenorha...1100.000000000000005     80.9     36     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0007088; P:regulation of mitosis; ISS:UniProtKB.
124O96020    404   CCNE2_HUMAN G1/S-specific cyclin-E2 OS=Homo s...2460.0000000000002     75.1     26     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.
125O01501    524   CCNE_CAEEL G1/S-specific cyclin-E OS=Caenorha...1290.0000000000009     73.6     33     57GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0042023; P:DNA endoreduplication; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0071850; P:mitotic cell cycle arrest; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:WormBase.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0010608; P:posttranscriptional regulation of gene expression; IMP:WormBase.::GO:0006468; P:protein phosphorylation; IMP:WormBase.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.
126P49707    407   CCNE1_CHICK G1/S-specific cyclin-E1 OS=Gallus...1270.000000000002     72     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
127Q9Z238    404   CCNE2_MOUSE G1/S-specific cyclin-E2 OS=Mus mu...2460.000000000003     72     25     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
128P50756    408   CCNE1_XENLA G1/S-specific cyclin-E1 OS=Xenopu...1110.000000000003     71.6     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
129Q91780    408   CCNE2_XENLA G1/S-specific cyclin-E2 OS=Xenopu...1110.000000000004     71.6     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
130O15995    424   CCNE_HEMPU G1/S-specific cyclin-E OS=pulcherr...980.000000000005     71.2     36     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
131P54733    709   CCNE_DROME G1/S-specific cyclin-E OS=Drosophi...1080.000000000007     71.2     32     56GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007307; P:eggshell chorion gene amplification; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0007259; P:JAK-STAT cascade; IGI:FlyBase.::GO:0007400; P:neuroblast fate determination; IMP:FlyBase.::GO:0048665; P:neuron fate specification; IDA:FlyBase.::GO:0007422; P:peripheral nervous system development; IEP:UniProtKB.::GO:0007277; P:pole cell development; IEP:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0006275; P:regulation of DNA replication; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; IGI:FlyBase.::GO:0001932; P:regulation of protein phosphorylation; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0045035; P:sensory organ precursor cell division; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IDA:FlyBase.
132P51944    777   CCNF_MOUSE Cyclin-F OS=Mus musculus (Mouse). ...1980.000000000008     71.2     28     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0001890; P:placenta development; IMP:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0000320; P:re-entry into mitotic cell cycle; IMP:MGI.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
133P39949    411   CCNE1_RAT G1/S-specific cyclin-E1 OS=Rattus n...2450.00000000001     70.1     26     47GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0001547; P:antral ovarian follicle growth; IEP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031670; P:cellular response to nutrient; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0045597; P:positive regulation of cell differentiation; IDA:RGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0014074; P:response to purine-containing compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.
134Q8K4F8    780   CCNF_RAT Cyclin-F OS=Rattus norvegicus (Rat)....1980.00000000001     70.9     28     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
135Q61457    408   CCNE1_MOUSE G1/S-specific cyclin-E1 OS=Mus mu...2430.00000000001     69.7     25     46GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:MGI.::GO:0016301; F:kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
136P43062    465   CG12_CANAX G1/S-specific cyclin CLN2 OS=Candi...1370.00000000001     69.7     27     58
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
137Q6K1Z6    390   CCF21_ORYSJ Putative cyclin-F2-1 OS=Oryza sat...2260.00000000005     67.8     24     48GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
138Q5XGG5    763   CCNF_XENTR Cyclin-F OS=Xenopus tropicalis (We...1880.00000000009     67.8     27     51GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
139P47794    410   CCNE1_DANRE G1/S-specific cyclin-E1 OS=Danio ...1870.0000000001     67     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016301; F:kinase activity; IDA:ZFIN.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
140Q7T0L6    761   CCNF_XENLA Cyclin-F OS=Xenopus laevis (Africa...1880.0000000001     67     27     51GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
141O42575    408   CCNE3_XENLA G1/S-specific cyclin-E3 OS=Xenopu...1100.0000000001     66.6     32     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
142P24864    410   CCNE1_HUMAN G1/S-specific cyclin-E1 OS=Homo s...1190.0000000002     65.9     29     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.
143P41002    786   CCNF_HUMAN Cyclin-F OS=Homo sapiens (Human). ...1360.0000000005     65.5     26     50GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
144Q6NYX6    764   CCNF_DANRE Cyclin-F OS=Danio rerio (Zebrafish...2160.000000001     64.3     24     46GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
145P55169    292   CCND1_CHICK G1/S-specific cyclin-D1 OS=Gallus...1640.000000001     62.8     24     51GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0070141; P:response to UV-A; ISS:UniProtKB.
146Q90459    291   CCND1_DANRE G1/S-specific cyclin-D1 OS=Danio ...2110.000000002     62     23     46GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0048593; P:camera-type eye morphogenesis; IMP:ZFIN.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
147A5PK16    788   CCNF_BOVIN Cyclin-F OS=Bos taurus (Bovine). G...1420.000000006     62     27     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010826; P:negative regulation of centrosome duplication; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
148Q10PQ9    469   CCSDS_ORYSJ Cyclin-SDS-like OS=Oryza sativa s...1450.000000006     61.6     30     54GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
149Q5SCB5    374   CCND_OSTTA Cyclin-D OS=Ostreococcus tauri. GN...2060.000000007     60.8     27     41GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
150Q8LHA8    356   CCD22_ORYSJ Cyclin-D2-2 OS=Oryza sativa subsp...1380.00000001     60.1     31     51GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
151Q5UNT4    539   YL670_MIMIV Putative serine/threonine-protein...1840.00000004     59.3     21     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
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