UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR210W

Length:

460

Number of sequences:

5887

Description:

YLR210W CLB4 SGDID:S000004200, Chr XII from 562008-563390, Genome Release 64-1-1, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P24871	460	CG24_YEAST G2/mitotic-specific cyclin-4 OS=Sa...	460	0	953	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; IMP:SGD.
2	P24870	427	CG23_YEAST G2/mitotic-specific cyclin-3 OS=Sa...	280	8e-122	369	62	81	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; IGI:SGD.
3	P24865	415	CG21_SCHPO G2/mitotic-specific cyclin cig1 OS...	268	9e-82	265	47	69	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:PomBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; NAS:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
4	P10815	482	CG23_SCHPO G2/mitotic-specific cyclin cdc13 O...	260	2e-76	253	46	67	GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:PomBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
5	P30284	478	CG21_EMENI G2/mitotic-specific cyclin-B OS=19...	299	9e-68	230	39	62	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
6	P36630	411	CG22_SCHPO G2/mitotic-specific cyclin cig2 OS...	266	1e-65	222	40	64	GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:PomBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000746; P:conjugation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.::GO:0007165; P:signal transduction; NAS:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; IGI:PomBase.
7	P24869	491	CG22_YEAST G2/mitotic-specific cyclin-2 OS=Sa...	264	9e-61	212	41	61	GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
8	P24868	471	CG21_YEAST G2/mitotic-specific cyclin-1 OS=Sa...	254	2e-60	210	42	62	GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IMP:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; IMP:SGD.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0008315; P:meiotic G2/MI transition; IEP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030472; P:mitotic spindle organization in nucleus; IGI:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
9	P24862	408	CCNB_PATVU G2/mitotic-specific cyclin-B OS=Pa...	294	6e-56	196	38	58	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
10	P07818	409	CCNB_ARBPU G2/mitotic-specific cyclin-B OS=Ar...	307	9e-56	196	37	59	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
11	O95067	398	CCNB2_HUMAN G2/mitotic-specific cyclin-B2 OS=...	259	1e-55	196	38	62	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
12	P47829	492	CG21_CANAX G2/mitotic-specific cyclin CYB1 OS...	268	2e-55	197	41	62	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
13	P13351	392	CCNB2_XENLA G2/mitotic-specific cyclin-B2 OS=...	306	2e-55	195	36	58	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
14	P13952	428	CCNB_SPISO G2/mitotic-specific cyclin-B OS=Sp...	291	2e-55	196	38	57	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
15	P51987	392	CCNB_HYDVD G2/mitotic-specific cyclin-B OS=Hy...	256	2e-55	194	39	60	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
16	P30276	398	CCNB2_MOUSE G2/mitotic-specific cyclin-B2 OS=...	221	2e-55	195	42	65	GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.::GO:0043029; P:T cell homeostasis; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI.
17	P24860	430	CCNB1_MOUSE G2/mitotic-specific cyclin-B1 OS=...	279	3e-55	195	37	59	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
18	Q08301	429	CCNB1_CRIGR G2/mitotic-specific cyclin-B1 OS=...	277	6e-55	194	38	58	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
19	O77689	398	CCNB2_BOVIN G2/mitotic-specific cyclin-B2 OS=...	251	6e-55	194	39	62	GO:0015630; C:microtubule cytoskeleton; ISS:AgBase.::GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
20	Q4R7A8	398	CCNB2_MACFA G2/mitotic-specific cyclin-B2 OS=...	259	1e-54	193	38	61	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
21	P37882	429	CCNB1_MESAU G2/mitotic-specific cyclin-B1 OS=...	277	3e-54	192	37	58	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
22	P37883	397	CCNB2_MESAU G2/mitotic-specific cyclin-B2 OS=...	221	3e-54	192	41	65	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
23	P30277	423	CCNB1_RAT G2/mitotic-specific cyclin-B1 OS=Ra...	277	7e-54	191	37	58	GO:0005813; C:centrosome; ISS:UniProtKB.
									GO:0019901; F:protein kinase binding; IPI:RGD.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071283; P:cellular response to iron(III) ion; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0048565; P:digestive tract development; IEP:RGD.::GO:0016572; P:histone phosphorylation; IDA:GOC.::GO:0010629; P:negative regulation of gene expression; IMP:RGD.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:RGD.::GO:0001556; P:oocyte maturation; IMP:RGD.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IDA:RGD.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:RGD.::GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:RGD.::GO:0006461; P:protein complex assembly; IDA:RGD.::GO:0060623; P:regulation of chromosome condensation; IMP:RGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0046680; P:response to DDT; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:RGD.
24	Q60FX9	394	CCNB2_ANGJA G2/mitotic-specific cyclin-B2 OS=...	274	3e-53	189	38	57	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
25	P29332	399	CCNB2_CHICK G2/mitotic-specific cyclin-B2 OS=...	302	4e-53	189	36	56	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0060317; P:cardiac epithelial to mesenchymal transition; IMP:AgBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
26	Q9DG97	401	CCNB1_ORYLU G2/mitotic-specific cyclin-B1 OS=...	304	5e-53	189	36	56	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
27	Q92162	397	CCNB1_CARAU G2/mitotic-specific cyclin-B1 OS=...	301	6e-53	188	35	54	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
28	P14635	433	CCNB1_HUMAN G2/mitotic-specific cyclin-B1 OS=...	276	9e-53	189	37	58	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000942; C:condensed nuclear chromosome outer kinetochore; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IDA:BHF-UCL.
									GO:0005113; F:patched binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; NAS:UniProtKB.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:BHF-UCL.::GO:0007080; P:mitotic metaphase plate congression; IMP:BHF-UCL.::GO:0000236; P:mitotic prometaphase; IDA:BHF-UCL.::GO:0043148; P:mitotic spindle stabilization; IMP:BHF-UCL.::GO:0051987; P:positive regulation of attachment of spindle microtubules to kinetochore; IMP:BHF-UCL.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
29	O93229	392	CCNB2_RANJA G2/mitotic-specific cyclin-B2 OS=...	296	1e-52	187	35	57	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
30	P13350	397	CCNB1_XENLA G2/mitotic-specific cyclin-B1 OS=...	305	1e-52	187	36	56	GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005113; F:patched binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
31	Q9DG99	382	CCNB2_ORYJA G2/mitotic-specific cyclin-B2 OS=...	290	1e-52	187	37	57	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.

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