Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR207W
Length:
833
Number of sequences:
5887
Description:
YLR207W HRD3 SGDID:S000004197, Chr XII from 556788-559289, Genome Release 64-1-1, Verified ORF, "Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q05787    833   HRD3_YEAST ERAD-associated E3 ubiquitin-prote...8330     1750     100     100GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IDA:SGD.::GO:0000838; C:Hrd1p ubiquitin ligase ERAD-M complex; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0034099; C:luminal surveillance complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030433; P:ER-associated protein catabolic process; IDA:SGD.::GO:0016567; P:protein ubiquitination; IDA:GOC.
2Q6FNV5    833   HRD3_CANGA ERAD-associated E3 ubiquitin-prote...8230     714     46     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
3Q80Z70    794   SE1L1_RAT Protein sel-1 homolog 1 OS=Rattus n...1200.003     44.7     28     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
4Q9Z2G6    790   SE1L1_MOUSE Protein sel-1 homolog 1 OS=Mus mu...12010     33.5     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
5Q9ESM7    794   SE1L1_MESAU Protein sel-1 homolog 1 OS=Mesocr...1206.7     33.9     26     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
6Q9UBV2    794   SE1L1_HUMAN Protein sel-1 homolog 1 OS=Homo s...1200.003     45.1     28     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
7Q5TEA6    688   SE1L2_HUMAN Protein sel-1 homolog 2 OS=Homo s...1460.13     39.7     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
8Q3V172    688   SE1L2_MOUSE Protein sel-1 homolog 2 OS=Mus mu...1460.39     38.1     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
9Q5XI05    688   SE1L2_RAT Protein sel-1 homolog 2 OS=Rattus n...1350.35     38.1     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
10Q9USV0    713   HRD3_SCHPO Putative ERAD-associated E3 ubiqui...1160.000000000004     73.6     37     56GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0016567; P:protein ubiquitination; NAS:PomBase.
11O13875    664   YE1A_SCHPO Uncharacterized Sel1-like repeat-c...1437.9     33.9     25     48
GO:0005488; F:binding; IEA:InterPro.
12P77234    325   YBEQ_ECOLI Uncharacterized protein ybeQ OS=Es...1600.088     39.7     29     44
GO:0005488; F:binding; IEA:InterPro.
13P60924    509   DELE_RAT Death ligand signal enhancer OS=Ratt...1260.11     39.7     30     46GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
14P34226    696   SKT5_YEAST Protein SKT5 OS=Saccharomyces cere...1340.13     39.7     25     49GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IMP:SGD.
GO:0000910; P:cytokinesis; TAS:SGD.::GO:0034221; P:fungal-type cell wall chitin biosynthetic process; IMP:SGD.::GO:0006970; P:response to osmotic stress; TAS:SGD.
15Q9FYF9    379   FB76_ARATH F-box protein At1g67340 OS=Arabido...1040.52     37.4     29     45GO:0005634; C:nucleus; IDA:TAIR.
GO:0008270; F:zinc ion binding; IEA:InterPro.
16P77296    184   YBET_ECOLI Uncharacterized protein ybeT OS=Es...820.54     36.2     24     52
GO:0005488; F:binding; IEA:InterPro.
17Q14154    515   DELE_HUMAN Death ligand signal enhancer OS=Ho...1275.8     34.3     28     43GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
18Q9DCV6    510   DELE_MOUSE Death ligand signal enhancer OS=Mu...1230.9     36.6     27     42GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005488; F:binding; IEA:InterPro.
GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
19Q9ZMS0    305   HCPD_HELPJ Putative beta-lactamase hcpD OS=He...741.7     35.4     28     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008800; F:beta-lactamase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
20Q9JZ25    467   Y1327_NEIMB Uncharacterized protein NMB1327 O...1031.9     35.4     29     47
GO:0005488; F:binding; IEA:InterPro.
21Q5UQH0    540   YR815_MIMIV Putative sel1-like repeat-contain...1172     35.4     28     48
GO:0005488; F:binding; IEA:InterPro.
22O24968    306   HCPD_HELPY Putative beta-lactamase hcpD OS=py...762.8     34.7     28     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008800; F:beta-lactamase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
23O25728    290   HCPC_HELPY Putative beta-lactamase hcpC OS=py...904.2     34.3     28     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008800; F:beta-lactamase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
24Q6IND7    341   LR2BP_XENLA LRP2-binding protein OS=Xenopus l...1096     33.9     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
25Q9ZKB5    290   HCPC_HELPJ Putative beta-lactamase hcpC OS=He...906.3     33.5     28     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008800; F:beta-lactamase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
26O25001    250   HCPA_HELPY Beta-lactamase hcpA OS=pylori). GN...486.5     33.5     31     54GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008800; F:beta-lactamase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
27Q6BML3    622   RMD9_DEBHA Protein RMD9, mitochondrial OS=008...1716.7     33.9     22     43GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
28P34288    1605   PAC1_CAEEL GTPase-activating protein pac-1 OS...1257.9     33.9     24     45GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
records
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