Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR205C
Length:
317
Number of sequences:
5887
Description:
YLR205C HMX1 SGDID:S000004195, Chr XII from 553677-552724, Genome Release 64-1-1, reverse complement, Verified ORF, "ER localized heme oxygenase, involved in heme degradation during iron starvation and in the oxidative stress response; expression is regulated by AFT1 and oxidative stress; relocates to the perinuclear region in the presence of oxidants"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32339    317   HMX1_YEAST Heme-binding protein HMX1 OS=Sacch...3170     655     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005640; C:nuclear outer membrane; IDA:SGD.
GO:0020037; F:heme binding; NAS:UniProtKB.::GO:0004392; F:heme oxygenase (decyclizing) activity; IDA:SGD.
GO:0042167; P:heme catabolic process; IMP:SGD.::GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0006979; P:response to oxidative stress; IMP:SGD.
2O19998    235   HO_RHOVL Heme oxygenase OS=Rhodella violacea ...2080.0000000001     63.9     25     45GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
3Q5R7E3    288   HMOX1_PONAB Heme oxygenase 1 OS=Pongo abelii ...2140.0000002     55.5     22     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
4Q8YVS7    238   HO1_NOSS1 Heme oxygenase 1 OS=Nostoc sp. (str...2570.0000004     53.9     21     42
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
5P51271    236   HO_PORPU Heme oxygenase OS=Porphyra purpurea....2470.0000004     53.9     23     43GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
6P09601    288   HMOX1_HUMAN Heme oxygenase 1 OS=Homo sapiens ...2140.0000005     53.9     22     43GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:BHF-UCL.::GO:0005792; C:microsome; ISS:BHF-UCL.
GO:0019899; F:enzyme binding; ISS:BHF-UCL.::GO:0020037; F:heme binding; IDA:BHF-UCL.::GO:0004392; F:heme oxygenase (decyclizing) activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0001525; P:angiogenesis; TAS:BHF-UCL.::GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0008219; P:cell death; ISS:BHF-UCL.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.::GO:0001935; P:endothelial cell proliferation; TAS:BHF-UCL.::GO:0034101; P:erythrocyte homeostasis; IMP:BHF-UCL.::GO:0007588; P:excretion; IC:BHF-UCL.::GO:0042167; P:heme catabolic process; IDA:BHF-UCL.::GO:0006788; P:heme oxidation; IDA:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; TAS:BHF-UCL.::GO:0034383; P:low-density lipoprotein particle clearance; TAS:BHF-UCL.::GO:0002686; P:negative regulation of leukocyte migration; TAS:BHF-UCL.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.::GO:0045080; P:positive regulation of chemokine biosynthetic process; TAS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IC:BHF-UCL.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; ISS:BHF-UCL.::GO:0042542; P:response to hydrogen peroxide; ISS:BHF-UCL.::GO:0035094; P:response to nicotine; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0014806; P:smooth muscle hyperplasia; TAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0002246; P:wound healing involved in inflammatory response; IMP:BHF-UCL.
7O70252    315   HMOX2_MOUSE Heme oxygenase 2 OS=Mus musculus ...2590.00002     48.9     18     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
8P14791    296   HMOX1_CHICK Heme oxygenase 1 OS=Gallus gallus...1960.00005     47.8     21     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
9P23711    315   HMOX2_RAT Heme oxygenase 2 OS=Rattus norvegic...2600.00007     47.4     18     42GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006788; P:heme oxidation; TAS:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
10Q1XDL5    238   HO_PORYE Heme oxygenase OS=Porphyra yezoensis...2460.0001     46.2     20     41GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
11P14901    289   HMOX1_MOUSE Heme oxygenase 1 OS=Mus musculus ...2130.0004     45.1     20     42GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.
GO:0071276; P:cellular response to cadmium ion; IDA:MGI.
12P43242    312   HMOX2_RABIT Heme oxygenase 2 OS=Oryctolagus c...2050.0006     44.3     19     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
13P06762    289   HMOX1_RAT Heme oxygenase 1 OS=Rattus norvegic...2160.0007     44.3     20     41GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:RGD.
GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:RGD.::GO:0004392; F:heme oxygenase (decyclizing) activity; IDA:BHF-UCL.::GO:0004630; F:phospholipase D activity; IDA:RGD.
GO:0001525; P:angiogenesis; IDA:RGD.::GO:0008219; P:cell death; IDA:BHF-UCL.::GO:0031670; P:cellular response to nutrient; IEP:RGD.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:RGD.::GO:0042167; P:heme catabolic process; IDA:RGD.::GO:0006788; P:heme oxidation; TAS:RGD.::GO:0043392; P:negative regulation of DNA binding; IDA:RGD.::GO:0032764; P:negative regulation of mast cell cytokine production; IDA:RGD.::GO:0043305; P:negative regulation of mast cell degranulation; IDA:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0006644; P:phospholipid metabolic process; TAS:RGD.::GO:0045766; P:positive regulation of angiogenesis; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:RGD.::GO:0008217; P:regulation of blood pressure; IDA:RGD.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD.
14P30519    316   HMOX2_HUMAN Heme oxygenase 2 OS=Homo sapiens ...2050.0007     44.3     18     41GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IDA:UniProtKB.::GO:0004392; F:heme oxygenase (decyclizing) activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0042167; P:heme catabolic process; TAS:Reactome.::GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.
15O78497    237   HO_GUITH Heme oxygenase OS=Guillardia theta (...2420.0008     43.9     21     44GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
16Q2PG53    316   HMOX2_MACFA Heme oxygenase 2 OS=Macaca fascic...2050.001     43.9     18     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
17P32394    288   HMOX1_PIG Heme oxygenase 1 OS=Sus scrofa (Pig...2140.002     43.1     21     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
18P74133    250   HO2_SYNY3 Heme oxygenase 2 OS=Synechocystis s...2840.002     42.7     20     41
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
19O73688    277   HMOX_TAKRU Heme oxygenase OS=Takifugu rubripe...2470.002     42.4     18     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
20P72849    240   HO1_SYNY3 Heme oxygenase 1 OS=Synechocystis s...2240.005     41.6     19     42
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
21Q5E9F2    289   HMOX1_BOVIN Heme oxygenase 1 OS=Bos taurus (B...2000.024     39.7     21     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.
22Q21534    1095   YVL7_CAEEL Uncharacterized NTE family protein...1380.2     37.4     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:InterPro.
GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
23P04535    521   COAT_BPT4 Major capsid protein OS=Enterobacte...1142.1     33.9     25     39GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
24P71119    215   HMUO_CORDI Heme oxygenase OS=gravis). GN=hmuO...1383.8     32.3     21     45
GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006788; P:heme oxidation; IEA:InterPro.
25Q6PUA2    1786   TAF1B_ARATH Transcription initiation factor T...679.3     32     34     52GO:0016020; C:membrane; IDA:TAIR.::GO:0005669; C:transcription factor TFIID complex; TAS:TAIR.
GO:0003712; F:transcription cofactor activity; TAS:TAIR.
GO:0016573; P:histone acetylation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009416; P:response to light stimulus; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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