Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR196W
Length:
576
Number of sequences:
5887
Description:
YLR196W PWP1 SGDID:S000004186, Chr XII from 543968-545698, Genome Release 64-1-1, Verified ORF, "Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P87053    605   POF1_SCHPO F-box/WD repeat-containing protein...2130.001     45.4     24     43GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
62Q08706    341   GBB_LYMST Guanine nucleotide-binding protein ...1470.001     44.7     28     46
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
63Q3B7M6    659   NEDD1_BOVIN Protein NEDD1 OS=Bos taurus (Bovi...1420.001     45.1     27     44
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
64Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...1570.001     45.1     25     45GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
65Q4X1Y0    510   PFS2_ASPFU Polyadenylation factor subunit 2 O...1110.002     45.1     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
66P47025    714   MDV1_YEAST Mitochondrial division protein 1 O...357.3     33.1     43     66GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0000266; P:mitochondrial fission; IMP:SGD.::GO:0000002; P:mitochondrial genome maintenance; IMP:SGD.
67Q5GIS3    341   GBB_PINFU Guanine nucleotide-binding protein ...1470.002     44.7     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
68Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...1650.002     45.1     24     45GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
69E9Q349    535   WDR25_MOUSE WD repeat-containing protein 25 O...1130.002     44.7     28     55
70P14197    478   AAC3_DICDI WD repeat-containing protein AAC3 ...1980.002     44.3     25     43
71Q7RY68    660   PFS2_NEUCR Polyadenylation factor subunit 2 O...1110.003     44.3     27     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
72O94365    494   UTP15_SCHPO U3 small nucleolar RNA-associated...1550.003     44.3     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0032040; C:small-subunit processome; ISS:PomBase.::GO:0005819; C:spindle; IDA:PomBase.::GO:0034455; C:t-UTP complex; ISS:PomBase.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
73Q9C1X0    297   YN55_SCHPO Uncharacterized WD repeat-containi...1070.003     43.5     30     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
74Q54MZ3    499   CDC20_DICDI Anaphase-promoting complex subuni...2450.003     43.9     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
75P49178    380   GBB_MAIZE Guanine nucleotide-binding protein ...1850.003     43.9     28     45
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
76Q6CSZ5    302   SEC13_KLULA Protein transport protein SEC13 O...2000.003     43.5     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
77Q9SYX2    1029   SPA1_ARATH Protein SUPPRESSOR OF PHYA-105 1 O...1730.003     44.3     25     44GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0009658; P:chloroplast organization; IMP:TAIR.::GO:0010100; P:negative regulation of photomorphogenesis; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IGI:TAIR.::GO:2000028; P:regulation of photoperiodism, flowering; IMP:TAIR.::GO:0010218; P:response to far red light; IEP:TAIR.::GO:0010114; P:response to red light; IEP:TAIR.::GO:0048575; P:short-day photoperiodism, flowering; IMP:TAIR.
78P20053    465   PRP4_YEAST U4/U6 small nuclear ribonucleoprot...1350.003     43.9     33     50GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
79Q2TZG4    610   PFS2_ASPOR Polyadenylation factor subunit 2 O...1110.003     43.9     28     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
80O13982    399   YEC8_SCHPO Uncharacterized WD repeat-containi...2680.004     43.5     23     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0000027; P:ribosomal large subunit assembly; ISS:PomBase.
81Q95RJ9    700   EBI_DROME F-box-like/WD repeat-containing pro...930.004     43.9     34     53GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
82Q9URY0    440   YTM1_SCHPO Ribosome biogenesis protein ytm1 O...2290.004     43.5     22     42GO:0015630; C:microtubule cytoskeleton; ISS:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0016043; P:cellular component organization; NAS:PomBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
83Q8H0T9    837   KTNB1_ARATH Katanin p80 WD40 repeat-containin...2060.004     43.9     25     44GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.
84Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...1740.005     43.5     24     50GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
85A3LQ86    467   YTM1_PICST Ribosome biogenesis protein YTM1 O...2030.005     43.5     23     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
86Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...1820.005     43.5     25     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
87Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...1740.005     43.5     24     50GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
88Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...1820.005     43.5     25     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
89C4Q0P6    417   LIS1_SCHMA Lissencephaly-1 homolog OS=Schisto...828.2     32.7     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
90Q2GVT8    1258   SEC31_CHAGB Protein transport protein SEC31 O...2240.005     43.5     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
91Q8C0P5    524   COR2A_MOUSE Coronin-2A OS=Mus musculus (Mouse...1000.006     43.1     28     46GO:0015629; C:actin cytoskeleton; IBA:RefGenome.::GO:0017053; C:transcriptional repressor complex; IBA:RefGenome.
GO:0051015; F:actin filament binding; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
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