UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR186W

Length:

252

Number of sequences:

5887

Description:

YLR186W EMG1 SGDID:S000004176, Chr XII from 523632-524390, Genome Release 64-1-1, Verified ORF, "Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q06287	252	NEP1_YEAST Ribosomal RNA small subunit methyl...	252	0	518	100	100	GO:0030686; C:90S preribosome; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005880; C:nuclear microtubule; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
									GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; TAS:UniProtKB.::GO:0019843; F:rRNA binding; IDA:UniProtKB.
									GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
2	Q9P8P7	267	NEP1_CANAX Ribosomal RNA small subunit methyl...	232	2e-143	410	82	92	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
3	Q96UP2	229	NEP1_CANGA Ribosomal RNA small subunit methyl...	253	1e-107	317	66	77	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
4	Q10107	359	MRA1_SCHPO Probable ribosomal RNA small subun...	243	2e-103	311	62	77	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; ISS:PomBase.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0000747; P:conjugation with cellular fusion; IGI:PomBase.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
5	Q92979	244	NEP1_HUMAN Ribosomal RNA small subunit methyl...	242	6e-75	234	51	65	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; IDA:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
6	Q9W4J5	252	NEP1_DROME Ribosomal RNA small subunit methyl...	220	5e-70	222	49	66	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
7	O35130	244	NEP1_MOUSE Ribosomal RNA small subunit methyl...	214	7e-70	221	52	67	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
8	Q9XX15	231	NEP1_CAEEL Ribosomal RNA small subunit methyl...	214	4e-65	209	46	68	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; ISS:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
9	A3DNG9	230	NEP1_STAMF Ribosomal RNA small subunit methyl...	191	4e-18	84.3	32	49
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
10	Q5JI44	220	NEP1_PYRKO Ribosomal RNA small subunit methyl...	189	4e-16	78.2	32	44
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
11	B6YTM6	219	NEP1_THEON Ribosomal RNA small subunit methyl...	181	0.000000000000001	77	31	45
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
12	C6A116	220	NEP1_THESM Ribosomal RNA small subunit methyl...	173	0.000000000000005	75.1	31	46
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
13	Q57977	205	NEP1_METJA Ribosomal RNA small subunit methyl...	183	0.00000000000001	73.6	28	46
									GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; IDA:UniProtKB.::GO:0019843; F:rRNA binding; IDA:UniProtKB.
14	Q9V0M0	232	NEP1_PYRAB Ribosomal RNA small subunit methyl...	229	0.00000000000003	73.2	27	44
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; IEA:HAMAP.::GO:0019843; F:rRNA binding; IEA:HAMAP.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
15	O50087	229	NEP1_PYRHO Ribosomal RNA small subunit methyl...	227	0.00000000000005	72.4	27	45
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
16	Q8U1E6	223	NEP1_PYRFU Ribosomal RNA small subunit methyl...	203	0.00000000000009	71.2	28	42
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
17	A0B5L3	226	NEP1_METTP Ribosomal RNA small subunit methyl...	151	0.0000000000006	68.9	29	50
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
18	Q97WJ0	218	NEP1_SULSO Ribosomal RNA small subunit methyl...	179	0.0000000000009	68.6	32	51
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
19	Q9YES9	224	NEP1_AERPE Ribosomal RNA small subunit methyl...	80	0.000000000005	66.6	40	56
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
20	O29524	219	NEP1_ARCFU Ribosomal RNA small subunit methyl...	162	0.00000000002	65.1	31	47
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
21	Q96YP4	219	NEP1_SULTO Ribosomal RNA small subunit methyl...	179	0.00000000004	63.9	31	48
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
22	A3MWJ1	221	NEP1_PYRCJ Ribosomal RNA small subunit methyl...	119	0.000000003	58.9	31	46
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
23	B1YD95	221	NEP1_THENV Ribosomal RNA small subunit methyl...	79	0.00000002	56.2	37	51
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
24	A1RVH0	221	NEP1_PYRIL Ribosomal RNA small subunit methyl...	119	0.0000008	52	36	46
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
25	Q9HJ48	222	NEP1_THEAC Ribosomal RNA small subunit methyl...	165	0.000001	51.2	22	48
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
26	Q8ZW45	221	NEP1_PYRAE Ribosomal RNA small subunit methyl...	116	0.000002	50.8	32	47
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
27	A4WMI3	221	NEP1_PYRAR Ribosomal RNA small subunit methyl...	119	0.000006	49.7	30	46
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
28	Q979E4	222	NEP1_THEVO Ribosomal RNA small subunit methyl...	158	0.000007	49.3	25	44
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
29	P18292	617	THRB_RAT Prothrombin OS=Rattus norvegicus (Ra...	69	1.2	34.3	33	43	GO:0005615; C:extracellular space; IDA:RGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:RGD.
									GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; TAS:RGD.
30	C5BQ32	376	DNAJ_TERTT Chaperone protein DnaJ OS=Teredini...	119	3.2	32.7	25	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.

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