Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR182W
Length:
803
Number of sequences:
5887
Description:
YLR182W SWI6 SGDID:S000004172, Chr XII from 517940-520351, Genome Release 64-1-1, Verified ORF, "Transcription cofactor, forms complexes with Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; cell wall stress induces phosphorylation by Mpk1p, which regulates Swi6p localization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P09959    803   SWI6_YEAST Regulatory protein SWI6 OS=Sacchar...8030     1640     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0030907; C:MBF transcription complex; IDA:SGD.::GO:0033309; C:SBF transcription complex; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IMP:SGD.
GO:0010845; P:positive regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.
2P40418    769   SWI6_KLULA Regulatory protein SWI6 OS=1267 / ...8332e-177     536     41     58
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3P01129    767   CDC10_SCHPO Start control protein cdc10 OS=Sc...4953e-49     189     30     49GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0030907; C:MBF transcription complex; TAS:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IC:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051038; P:negative regulation of transcription during meiosis; IDA:UniProtKB.::GO:0007068; P:negative regulation of transcription during mitosis; IDA:UniProtKB.::GO:0051039; P:positive regulation of transcription during meiosis; IDA:UniProtKB.::GO:0045897; P:positive regulation of transcription during mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IGI:PomBase.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:PomBase.::GO:0009303; P:rRNA transcription; IDA:UniProtKB.
4P41412    657   RES2_SCHPO Cell division cycle-related protei...3891e-23     110     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0030907; C:MBF transcription complex; TAS:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IC:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0051037; P:regulation of transcription during meiosis; IDA:PomBase.::GO:0045896; P:regulation of transcription during mitosis; IDA:PomBase.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:PomBase.
5P33520    637   RES1_SCHPO Cell division cycle-related protei...2013e-20     99.4     29     48GO:0030907; C:MBF transcription complex; TAS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; TAS:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0045897; P:positive regulation of transcription during mitosis; IDA:PomBase.::GO:0051037; P:regulation of transcription during meiosis; TAS:PomBase.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; IMP:PomBase.
6P39678    833   MBP1_YEAST Transcription factor MBP1 OS=Sacch...2012e-16     87.4     26     49GO:0030907; C:MBF transcription complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.
7P25302    1093   SWI4_YEAST Regulatory protein SWI4 OS=Sacchar...2210.0000000000008     76.3     26     45GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0033309; C:SBF transcription complex; IMP:SGD.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IPI:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.
8P39679    754   MBP1_KLULA Transcription factor MBP1 OS=1267 ...4770.00000000002     71.2     21     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9O35516    2470   NOTC2_MOUSE Neurogenic locus notch homolog pr...910.0004     47.8     33     53GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0030326; P:embryonic limb morphogenesis; IGI:MGI.::GO:0072104; P:glomerular capillary formation; IEP:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0006959; P:humoral immune response; IGI:MGI.::GO:0002437; P:inflammatory response to antigenic stimulus; IGI:MGI.::GO:0072602; P:interleukin-4 secretion; IGI:MGI.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0072014; P:proximal tubule development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; IDA:UniProtKB.
10Q04721    2471   NOTC2_HUMAN Neurogenic locus notch homolog pr...910.0004     47.8     33     53GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003706; F:ligand-regulated transcription factor activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; NAS:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0046849; P:bone remodeling; IMP:UniProtKB.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; IEP:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0019827; P:stem cell maintenance; TAS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
11Q9QW30    2471   NOTC2_RAT Neurogenic locus notch homolog prot...910.0004     47.8     33     53GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; TAS:RGD.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0001709; P:cell fate determination; IDA:RGD.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0050793; P:regulation of developmental process; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q9EP71    979   RAI14_MOUSE Ankycorbin OS=Mus musculus (Mouse...743     35     28     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
13Q12013    749   AKR2_YEAST Probable palmitoyltransferase AKR2...570.002     45.4     44     58GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016409; F:palmitoyltransferase activity; ISS:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0018345; P:protein palmitoylation; ISS:SGD.
14Q4UMH6    1179   Y381_RICFE Putative ankyrin repeat protein RF...702.9     35     33     50
GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
15Q5U312    978   RAI14_RAT Ankycorbin OS=Rattus norvegicus (Ra...742.6     35.4     28     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
16Q6UB98    2062   ANR12_HUMAN Ankyrin repeat domain-containing ...480.004     44.7     46     60GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
17Q07E43    476   ASZ1_DASNO Ankyrin repeat, SAM and basic leuc...2020.006     43.5     23     40GO:0071546; C:pi-body; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.::GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0007140; P:male meiosis; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
18Q9TU71    319   ANKR1_RABIT Ankyrin repeat domain-containing ...470.009     42.7     45     60
19Q8Q0U0    360   Y045_METMA Putative ankyrin repeat protein MM...1021.6     35.4     31     48
20Q4UKX2    395   Y950_RICFE Putative ankyrin repeat protein RF...2000.011     42.7     28     45
GO:0016787; F:hydrolase activity; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
21Q4V869    286   ACBD6_XENLA Acyl-CoA-binding domain-containin...440.016     42     45     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
22Q7M6U3    1450   TEX14_MOUSE Inactive serine/threonine-protein...680.018     42.4     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045171; C:intercellular bridge; IDA:UniProtKB.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0043063; P:intercellular bridge organization; IDA:UniProtKB.::GO:0007140; P:male meiosis; IMP:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.::GO:0051306; P:mitotic sister chromatid separation; IMP:UniProtKB.::GO:0032466; P:negative regulation of cytokinesis; IDA:MGI.::GO:0032091; P:negative regulation of protein binding; IDA:MGI.
23Q66JD7    286   ACBD6_XENTR Acyl-CoA-binding domain-containin...440.022     41.2     45     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
24Q15327    319   ANKR1_HUMAN Ankyrin repeat domain-containing ...470.025     41.2     45     60GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031674; C:I band; ISS:BHF-UCL.
GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:BHF-UCL.
GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071347; P:cellular response to interleukin-1; IDA:BHF-UCL.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.::GO:0035994; P:response to muscle stretch; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; NAS:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
25Q7ZT11    319   ANKR1_CHICK Ankyrin repeat domain-containing ...620.025     41.2     42     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
26Q3ZBX7    319   ANKR1_BOVIN Ankyrin repeat domain-containing ...470.025     41.2     43     60
27Q54HW1    232   PSD10_DICDI 26S proteasome non-ATPase regulat...2190.028     40.8     26     44
28Q865U8    319   ANKR1_PIG Ankyrin repeat domain-containing pr...470.03     41.2     43     60GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003779; F:actin binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.
29Q69ZU8    712   ANKR6_MOUSE Ankyrin repeat domain-containing ...2200.03     41.6     24     40GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:MGI.::GO:2000096; P:positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; IDA:MGI.
30Q8N9V6    530   ANR53_HUMAN Ankyrin repeat domain-containing ...470.03     41.6     43     60
31Q01484    3957   ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human)....481.4     36.2     38     56GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.
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