Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR176C
Length:
811
Number of sequences:
5887
Description:
YLR176C RFX1 SGDID:S000004166, Chr XII from 510232-507797, Genome Release 64-1-1, reverse complement, Verified ORF, "Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P48743    811   RFX1_YEAST RFX-like DNA-binding protein RFX1 ...8110     1641     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2P48383    766   SAK1_SCHPO Protein sak1 OS=Schizosaccharomyce...1191e-24     114     43     63GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0003677; F:DNA binding; TAS:PomBase.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:PomBase.
GO:0031536; P:positive regulation of exit from mitosis; IMP:PomBase.
3P48379    717   RFX2_MOUSE DNA-binding protein RFX2 OS=Mus mu...1760.019     42.4     19     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4B2GV50    692   RFX2_RAT DNA-binding protein RFX2 OS=Rattus n...1760.01     43.1     19     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q4R3Z4    723   RFX2_MACFA DNA-binding protein RFX2 OS=Macaca...1770.001     46.2     23     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q33E94    735   RFX4_HUMAN Transcription factor RFX4 OS=Homo ...3080.000007     53.5     20     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7P48378    723   RFX2_HUMAN DNA-binding protein RFX2 OS=Homo s...1760.002     45.8     20     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:ProtInc.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q09555    805   DAF19_CAEEL RFX-like transcription factor daf...4380.00000000000005     79.7     21     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0043053; P:dauer entry; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q7TNK1    735   RFX4_MOUSE Transcription factor RFX4 OS=Mus m...3080.000003     54.7     20     41GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.::GO:0021516; P:dorsal spinal cord development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q5RDR2    704   RFX2_PONAB DNA-binding protein RFX2 OS=Pongo ...1770.0008     46.6     23     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11A6QLW9    707   RFX2_BOVIN DNA-binding protein RFX2 OS=Bos ta...1750.002     45.4     19     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q32NR3    694   RFX2_XENLA DNA-binding protein RFX2 OS=Xenopu...1770.0002     48.5     21     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13B1WAV2    694   RFX2_XENTR DNA-binding protein RFX2 OS=Xenopu...1770.0002     48.9     21     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14P48377    963   RFX1_MOUSE MHC class II regulatory factor RFX...1660.013     42.7     19     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q5EAP5    734   RFX2_DANRE DNA-binding protein RFX2 OS=Danio ...1750.1     40     19     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P22670    979   RFX1_HUMAN MHC class II regulatory factor RFX...1780.0004     47.8     20     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006955; P:immune response; TAS:ProtInc.
17Q4R3I8    749   RFX3_MACFA Transcription factor RFX3 OS=Macac...1730.002     45.1     19     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0060285; P:ciliary cell motility; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
18A0JMF8    765   RFX3_DANRE Transcription factor RFX3 OS=Danio...730.0000000000002     77.8     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0060285; P:ciliary cell motility; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
19Q0V9K5    749   RFX3_XENTR Transcription factor RFX3 OS=Xenop...3740.0000000000002     77.8     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0060285; P:ciliary cell motility; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
20P48380    749   RFX3_HUMAN Transcription factor RFX3 OS=Homo ...1730.002     45.4     19     44GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IC:BHF-UCL.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060285; P:ciliary cell motility; ISS:UniProtKB.::GO:0042384; P:cilium assembly; ISS:BHF-UCL.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:2000078; P:positive regulation of type B pancreatic cell development; ISS:BHF-UCL.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
21P48381    749   RFX3_MOUSE Transcription factor RFX3 OS=Mus m...1730.002     45.4     19     44GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IC:BHF-UCL.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0042384; P:cilium assembly; IMP:BHF-UCL.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:2000078; P:positive regulation of type B pancreatic cell development; IMP:BHF-UCL.::GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB.::GO:0072560; P:type B pancreatic cell maturation; IMP:BHF-UCL.
22Q8C7R7    927   RFX6_MOUSE DNA-binding protein RFX6 OS=Mus mu...1663.3     35     22     39GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; IMP:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; IMP:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; IMP:UniProtKB.
23A2BGA0    735   RFX4_DANRE Transcription factor RFX4 OS=Danio...2110.000001     55.8     23     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q2KHR2    1363   RFX7_HUMAN DNA-binding protein RFX7 OS=Homo s...790.000000000004     73.9     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
25D2HNW6    928   RFX6_AILME DNA-binding protein RFX6 OS=Ailuro...1070.000000000007     72.8     38     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB.
26Q8HWS3    928   RFX6_HUMAN DNA-binding protein RFX6 OS=Homo s...1030.000000000009     72.8     36     54GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB.
27Q6ZV50    586   RFX8_HUMAN DNA-binding protein RFX8 OS=Homo s...690.00000000001     71.6     45     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q5RJA1    848   RFX6_DANRE DNA-binding protein RFX6 OS=Danio ...830.00000000003     70.9     41     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB.
29P48382    616   RFX5_HUMAN DNA-binding protein RFX5 OS=Homo s...790.00000000005     70.1     39     61GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30D3YU81    596   RFX8_MOUSE DNA-binding protein RFX8 OS=Mus mu...690.0000000003     67.4     43     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q68CP9    1835   ARID2_HUMAN AT-rich interactive domain-contai...840.003     45.1     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:GDB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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