Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR175W
Length:
483
Number of sequences:
5887
Description:
YLR175W CBF5 SGDID:S000004165, Chr XII from 506134-507585, Genome Release 64-1-1, Verified ORF, "Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33322    483   CBF5_YEAST H/ACA ribonucleoprotein complex su...4830     983     100     100GO:0030686; C:90S preribosome; IDA:SGD.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IC:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0009982; F:pseudouridine synthase activity; IMP:SGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000495; P:box H/ACA snoRNA 3'-end processing; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031118; P:rRNA pseudouridine synthesis; IMP:SGD.::GO:0031120; P:snRNA pseudouridine synthesis; IMP:SGD.
2O13473    474   CBF5_KLULA Centromere/microtubule-binding pro...4010     761     91     97GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
3O43101    479   CBF5_CANAL Centromere/microtubule-binding pro...4230     755     84     92GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
4O43102    487   CBF5_ASPFU Centromere/microtubule-binding pro...4420     678     71     84GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
5O43100    481   CBF5_EMENI Centromere/microtubule-binding pro...4210     660     76     87GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
6O14007    474   CBF5_SCHPO H/ACA ribonucleoprotein complex su...3840     632     80     92GO:0031429; C:box H/ACA snoRNP complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0034513; F:box H/ACA snoRNA binding; IC:PomBase.::GO:0009982; F:pseudouridine synthase activity; ISS:PomBase.
GO:0000495; P:box H/ACA snoRNA 3'-end processing; ISS:PomBase.::GO:0031118; P:rRNA pseudouridine synthesis; ISS:PomBase.::GO:0031120; P:snRNA pseudouridine synthesis; ISS:PomBase.::GO:0006399; P:tRNA metabolic process; NAS:PomBase.
7Q5ZJH9    516   DKC1_CHICK H/ACA ribonucleoprotein complex su...4270     598     68     81GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0007004; P:telomere maintenance via telomerase; TAS:Reactome.
8Q9ESX5    509   DKC1_MOUSE H/ACA ribonucleoprotein complex su...4110     592     68     83GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; TAS:MGI.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0004730; F:pseudouridylate synthase activity; TAS:MGI.::GO:0003723; F:RNA binding; TAS:MGI.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0000154; P:rRNA modification; TAS:MGI.
9Q54T81    540   DKC1_DICDI Probable H/ACA ribonucleoprotein c...4240     588     66     80GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005730; C:nucleolus; ISS:dictyBase.::GO:0005697; C:telomerase holoenzyme complex; ISS:dictyBase.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:dictyBase.::GO:0003720; F:telomerase activity; ISS:dictyBase.
GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0051726; P:regulation of cell cycle; ISS:dictyBase.::GO:0006364; P:rRNA processing; ISS:dictyBase.::GO:0007004; P:telomere maintenance via telomerase; ISS:dictyBase.
10P40615    509   DKC1_RAT H/ACA ribonucleoprotein complex subu...3990     587     69     84GO:0015030; C:Cajal body; IDA:RGD.::GO:0005730; C:nucleolus; IDA:RGD.::GO:0005732; C:small nucleolar ribonucleoprotein complex; IDA:RGD.
GO:0005515; F:protein binding; IPI:RGD.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008283; P:cell proliferation; IDA:RGD.::GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
11O60832    514   DKC1_HUMAN H/ACA ribonucleoprotein complex su...4240     586     67     82GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005697; C:telomerase holoenzyme complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0003720; F:telomerase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; TAS:ProtInc.::GO:0007004; P:telomere maintenance via telomerase; TAS:Reactome.
12O44081    508   DKC1_DROME H/ACA ribonucleoprotein complex su...4090     586     67     80GO:0005730; C:nucleolus; IDA:FlyBase.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007281; P:germ cell development; IMP:FlyBase.::GO:0001522; P:pseudouridine synthesis; IMP:FlyBase.::GO:0006364; P:rRNA processing; IMP:FlyBase.::GO:0035220; P:wing disc development; IMP:FlyBase.
13Q9LD90    565   CBF5_ARATH H/ACA ribonucleoprotein complex su...3830     585     73     86GO:0005829; C:cytosol; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; TAS:TAIR.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
14Q60YA8    445   DKC1_CAEBR Putative H/ACA ribonucleoprotein c...3880     570     67     82GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
15O17919    445   DKC1_CAEEL Putative H/ACA ribonucleoprotein c...3850     566     66     82GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
16Q8TZ08    338   TRUB_METKA Probable tRNA pseudouridine syntha...3082e-90     285     46     66
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
17Q9V1A5    334   TRUB_PYRAB Probable tRNA pseudouridine syntha...3067e-89     281     46     64
GO:0009982; F:pseudouridine synthase activity; IEA:HAMAP.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.::GO:0031119; P:tRNA pseudouridine synthesis; IEA:HAMAP.
18O59357    334   TRUB_PYRHO Probable tRNA pseudouridine syntha...3065e-87     276     45     64
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
19Q5JJE8    338   TRUB_PYRKO Probable tRNA pseudouridine syntha...3066e-87     276     44     64
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
20Q46GC3    338   TRUB_METBF Probable tRNA pseudouridine syntha...3221e-86     276     44     65
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
21Q7LWY0    340   TRUB_PYRFU Probable tRNA pseudouridine syntha...3061e-86     276     44     64
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
22O26140    324   TRUB_METTH Probable tRNA pseudouridine syntha...3082e-85     272     46     65
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
23O30001    325   TRUB_ARCFU Probable tRNA pseudouridine syntha...3062e-85     272     44     64
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
24C5A255    334   TRUB_THEGJ Probable tRNA pseudouridine syntha...3066e-85     271     43     63
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
25B6YSP4    334   TRUB_THEON Probable tRNA pseudouridine syntha...3061e-84     271     43     63
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
26Q8TRR5    338   TRUB_METAC Probable tRNA pseudouridine syntha...3271e-84     270     43     63
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
27A6VHV2    333   TRUB_METM7 Probable tRNA pseudouridine syntha...3203e-83     267     46     62
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
28Q8PV20    338   TRUB_METMA Probable tRNA pseudouridine syntha...3273e-83     267     43     62
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
29Q57612    336   TRUB_METJA Probable tRNA pseudouridine syntha...3223e-83     267     44     63
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
30A9A8X7    333   TRUB_METM6 Probable tRNA pseudouridine syntha...3208e-83     266     46     62
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
31A4G0N3    333   TRUB_METM5 Probable tRNA pseudouridine syntha...3201e-82     265     45     62
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
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