UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR172C

Length:

300

Number of sequences:

5887

Description:

YLR172C DPH5 SGDID:S000004162, Chr XII from 502162-501260, Genome Release 64-1-1, reverse complement, Verified ORF, "Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	C4KGZ7	257	DPHB_SULIK Diphthine synthase OS=Sulfolobus i...	264	1e-20	92.8	28	48
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
62	C3N5D1	257	DPHB_SULIA Diphthine synthase OS=Sulfolobus i...	264	1e-20	92.8	28	48
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
63	Q97TX8	257	DPHB_SULSO Diphthine synthase OS=P2). GN=dphB...	264	3e-19	88.6	27	47
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
64	Q8ZXR9	254	DPHB_PYRAE Diphthine synthase OS=/ NBRC 10082...	243	3e-17	82.8	28	46
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
65	A1RU15	249	DPHB_PYRIL Diphthine synthase OS=Pyrobaculum ...	226	0.0000000000001	72.8	27	46
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
66	Q9YDI2	294	DPHB_AERPE Diphthine synthase OS=100138 / K1)...	285	0.0000000000001	73.2	28	45
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
67	B1YAU2	253	DPHB_THENV Diphthine synthase OS=Thermoproteu...	226	0.000000000003	68.6	26	44
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
68	A3MU14	251	DPHB_PYRCJ Diphthine synthase OS=Pyrobaculum ...	225	0.0000000009	61.6	28	45
									GO:0004164; F:diphthine synthase activity; IEA:EC.
									GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
69	B0BTC2	486	CYSG_ACTPJ Siroheme synthase OS=Actinobacillu...	256	0.00002	49.3	25	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
70	B3GZA0	486	CYSG_ACTP7 Siroheme synthase OS=Actinobacillu...	255	0.00006	48.1	23	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
71	A9LZ77	480	CYSG_NEIM0 Siroheme synthase OS=Neisseria men...	284	0.0009	44.3	23	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
72	P57001	486	CYSG_NEIMA Siroheme synthase OS=Neisseria men...	255	0.001	43.9	23	38
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
73	P95370	483	CYSG_NEIMB Siroheme synthase OS=Neisseria men...	280	0.001	43.9	23	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
74	Q6D1A4	480	CYSG1_ERWCT Siroheme synthase 1 OS=BAA-672) (...	260	0.002	42.7	22	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
75	A1KU10	483	CYSG_NEIMF Siroheme synthase OS=FAM18). GN=cy...	258	0.003	42.7	22	38
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
76	A6TD45	471	CYSG1_KLEP7 Siroheme synthase 1 OS=78578). GN...	299	0.003	42.4	24	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
77	A7MJ67	471	CYSG1_CROS8 Siroheme synthase 1 OS=Cronobacte...	286	0.008	41.2	22	40
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
78	A1JJS8	472	CYSG1_YERE8 Siroheme synthase 1 OS=Yersinia e...	253	0.009	40.8	22	35
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
79	Q4K9V8	464	CYSG_PSEF5 Siroheme synthase OS=Pseudomonas f...	262	0.9	34.7	23	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
80	P29564	231	SUMT_METIV Uroporphyrinogen-III C-methyltrans...	263	1	34.3	22	37
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
81	Q58375	242	SUMT_METJA Uroporphyrinogen-III C-methyltrans...	201	1.5	33.5	24	43
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
82	O34744	257	SUMT_BACSU Uroporphyrinogen-III C-methyltrans...	168	1.6	33.5	24	46
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
83	Q98RF5	222	RSMI_MYCPU Ribosomal RNA small subunit methyl...	128	1.7	33.5	29	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
84	A4TPZ1	472	CYSG2_YERPP Siroheme synthase 2 OS=Yersinia p...	257	2.3	33.5	21	37
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
85	Q1CLS2	472	CYSG1_YERPN Siroheme synthase 1 OS=Yersinia p...	257	2.3	33.5	21	37
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
86	Q58181	230	CBIL_METJA Probable cobalt-precorrin-2 C(20)-...	116	2.5	33.1	25	48
									GO:0043781; F:cobalt-factor II C20-methyltransferase activity; IEA:EC.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
87	Q6F8G6	457	CYSG_ACIAD Siroheme synthase OS=Acinetobacter...	266	2.9	33.1	21	39
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
88	A7FLY4	472	CYSG1_YERP3 Siroheme synthase 1 OS=Yersinia p...	257	3	33.1	21	37
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
89	Q66EC9	472	CYSG1_YERPS Siroheme synthase 1 OS=Yersinia p...	257	3.1	33.1	21	37
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
90	B2D0J4	775	VDPP4_APIME Venom dipeptidyl peptidase 4 OS=A...	77	3.4	33.1	34	40	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
91	O29876	198	OGG1_ARCFU Probable N-glycosylase/DNA lyase O...	78	4.6	32	27	46
									GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:InterPro.
									GO:0006284; P:base-excision repair; IEA:InterPro.

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