rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O31766 | 428 | YMFH_BACSU Uncharacterized zinc protease ymfH... | 173 | 0.0000001 | 57.4 | 26 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 62 | Q6CWJ6 | 360 | QCR2_KLULA Cytochrome b-c1 complex subunit 2,... | 300 | 0.0000002 | 56.6 | 22 | 42 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 63 | Q6C2E3 | 417 | QCR2_YARLI Cytochrome b-c1 complex subunit 2,... | 412 | 0.0000003 | 56.2 | 23 | 43 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 64 | P22817 | 990 | IDE_DROME Insulin-degrading enzyme OS=Drosoph... | 243 | 0.0000006 | 55.8 | 26 | 40 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 65 | Q9JHR7 | 1019 | IDE_MOUSE Insulin-degrading enzyme OS=Mus mus... | 129 | 0.0000006 | 55.8 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 66 | Q88A79 | 779 | PQQF_PSESM Coenzyme PQQ synthesis protein F O... | 126 | 0.0000007 | 55.5 | 31 | 48 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 67 | P71006 | 426 | ALBF_BACSU Putative zinc protease AlbF OS=Bac... | 200 | 0.0000008 | 54.7 | 26 | 42 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030152; P:bacteriocin biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 68 | Q24K02 | 1019 | IDE_BOVIN Insulin-degrading enzyme OS=Bos tau... | 129 | 0.0000009 | 55.1 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 69 | P14735 | 1019 | IDE_HUMAN Insulin-degrading enzyme OS=Homo sa... | 129 | 0.000001 | 55.1 | 29 | 48 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 70 | P45181 | 926 | PQQL_HAEIN Probable zinc protease pqqL OS=Hae... | 218 | 0.000001 | 54.7 | 25 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 71 | P35559 | 1019 | IDE_RAT Insulin-degrading enzyme OS=Rattus no... | 129 | 0.000002 | 54.3 | 29 | 48 | GO:0009986; C:cell surface; IDA:RGD.::GO:0031597; C:cytosolic proteasome complex; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005782; C:peroxisomal matrix; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IPI:RGD.::GO:0031626; F:beta-endorphin binding; IMP:RGD.::GO:0043559; F:insulin binding; IMP:RGD.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0042447; P:hormone catabolic process; IDA:RGD.::GO:0045861; P:negative regulation of proteolysis; IDA:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:RGD. | 72 | Q8ZMB5 | 962 | PTRA_SALTY Protease 3 OS=Salmonella typhimuri... | 120 | 0.000003 | 53.5 | 28 | 48 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 73 | Q75CW5 | 366 | QCR2_ASHGO Cytochrome b-c1 complex subunit 2,... | 181 | 0.000003 | 52.4 | 27 | 44 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 74 | Q8RKH2 | 427 | ALBF_BACIU Putative zinc protease AlbF OS=Bac... | 209 | 0.000004 | 52.4 | 26 | 42 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030152; P:bacteriocin biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 75 | O43847 | 1150 | NRDC_HUMAN Nardilysin OS=Homo sapiens (Human)... | 225 | 0.000006 | 52.4 | 23 | 41 | GO:0009986; C:cell surface; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB. | | | | | | | | | | GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007528; P:neuromuscular junction development; TAS:ProtInc.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL. | 76 | Q6FSJ3 | 364 | QCR2_CANGA Cytochrome b-c1 complex subunit 2,... | 207 | 0.000008 | 51.6 | 26 | 48 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 77 | P42789 | 596 | SDP_EIMBO Sporozoite developmental protein OS... | 191 | 0.00001 | 51.6 | 26 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 78 | Q8BHG1 | 1161 | NRDC_MOUSE Nardilysin OS=Mus musculus (Mouse)... | 204 | 0.00001 | 52 | 23 | 41 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 79 | P47245 | 1161 | NRDC_RAT Nardilysin OS=Rattus norvegicus (Rat... | 204 | 0.00001 | 51.6 | 23 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 80 | Q5R4H6 | 1152 | NRDC_PONAB Nardilysin OS=Pongo abelii (Sumatr... | 204 | 0.00001 | 51.6 | 23 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 81 | P31828 | 931 | PQQL_ECOLI Probable zinc protease pqqL OS=Esc... | 232 | 0.00002 | 51.2 | 21 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 82 | P40851 | 1208 | AXL1_YEAST Putative protease AXL1 OS=Saccharo... | 226 | 0.00002 | 50.8 | 24 | 41 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007120; P:axial cellular bud site selection; IMP:SGD.::GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 83 | P55680 | 447 | Y4WB_RHISN Uncharacterized zinc protease-like... | 407 | 0.00002 | 50.1 | 22 | 40 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 84 | O14077 | 969 | MU138_SCHPO Putative zinc protease mug138 OS=... | 226 | 0.00003 | 50.4 | 26 | 41 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase. | 85 | Q06010 | 1027 | STE23_YEAST A-factor-processing enzyme OS=Sac... | 225 | 0.00003 | 50.4 | 22 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007323; P:peptide pheromone maturation; IGI:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 86 | Q8Z418 | 962 | PTRA_SALTI Protease 3 OS=Salmonella typhi. GN... | 120 | 0.00004 | 50.1 | 28 | 47 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 87 | O22941 | 970 | PXM16_ARATH Zinc-metallopeptidase, peroxisoma... | 223 | 0.00005 | 49.3 | 22 | 42 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 88 | P27508 | 761 | PQQF_KLEPN Coenzyme PQQ synthesis protein F O... | 125 | 0.0001 | 48.5 | 31 | 45 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 89 | P48053 | 995 | YPD1_CAEEL Uncharacterized protein C05D11.1 O... | 175 | 0.0001 | 48.5 | 26 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 90 | P86201 | 114 | QCR1_MESAU Cytochrome b-c1 complex subunit 1,... | 35 | 0.0003 | 44.3 | 51 | 69 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 91 | Q6BPY6 | 376 | QCR2_DEBHA Cytochrome b-c1 complex subunit 2,... | 229 | 0.0006 | 45.4 | 24 | 45 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. |