UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR134W

Length:

563

Number of sequences:

5887

Description:

YLR134W PDC5 SGDID:S000004124, Chr XII from 410723-412414, Genome Release 64-1-1, Verified ORF, "Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q10MW3	605	PDC2_ORYSJ Pyruvate decarboxylase isozyme 2 O...	572	3e-89	293	35	51
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
32	P28516	610	PDC1_MAIZE Pyruvate decarboxylase isozyme 1 O...	567	7e-89	292	34	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.
33	Q92345	569	PDC2_SCHPO Probable pyruvate decarboxylase C1...	572	2e-85	282	33	49
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0009063; P:cellular amino acid catabolic process; ISS:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.
34	P51846	614	PDC2_TOBAC Pyruvate decarboxylase isozyme 2 O...	604	7e-85	282	34	49
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
35	P51850	593	PDC1_PEA Pyruvate decarboxylase isozyme 1 OS=...	570	9e-85	281	32	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
36	A2YQ76	587	PDC3_ORYSI Pyruvate decarboxylase isozyme 3 O...	573	2e-83	277	34	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
37	Q0D3D2	587	PDC3_ORYSJ Pyruvate decarboxylase isozyme 3 O...	573	2e-82	275	34	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
38	Q9P7P6	572	PDC3_SCHPO Probable pyruvate decarboxylase C1...	569	2e-77	261	31	49	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0009063; P:cellular amino acid catabolic process; ISS:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.
39	P33287	570	PDC_NEUCR Pyruvate decarboxylase OS=1257 / FG...	569	1e-71	246	29	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
40	P06672	568	PDC_ZYMMO Pyruvate decarboxylase OS=Zymomonas...	568	2e-64	226	30	48
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
41	P51845	418	PDC1_TOBAC Pyruvate decarboxylase isozyme 1 O...	424	7e-61	213	33	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
42	P51852	545	DCIP_AZOBR Indole-3-pyruvate decarboxylase OS...	548	2e-41	161	26	43
									GO:0047434; F:indolepyruvate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
43	P51851	405	PDC2_PEA Pyruvate decarboxylase isozyme 2 OS=...	410	8e-41	157	30	46
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
44	Q05327	202	PDC3_MAIZE Pyruvate decarboxylase isozyme 3 O...	206	4e-23	101	34	50
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.
45	P37251	574	ILVB_BACSU Acetolactate synthase large subuni...	490	2e-20	98.6	25	41
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
46	Q8CHM7	581	HACL1_RAT 2-hydroxyacyl-CoA lyase 1 OS=Rattus...	546	3e-20	97.8	23	41	GO:0005777; C:peroxisome; IDA:HGNC.
									GO:0016830; F:carbon-carbon lyase activity; IDA:HGNC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IDA:HGNC.
									GO:0001561; P:fatty acid alpha-oxidation; IDA:HGNC.
47	Q9QXE0	581	HACL1_MOUSE 2-hydroxyacyl-CoA lyase 1 OS=Mus ...	542	4e-20	97.8	22	42	GO:0005777; C:peroxisome; TAS:MGI.
									GO:0016830; F:carbon-carbon lyase activity; ISS:HGNC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; ISS:HGNC.
									GO:0001561; P:fatty acid alpha-oxidation; ISS:HGNC.
48	O06335	552	ILVB2_MYCTU Putative acetolactate synthase la...	491	4e-20	97.8	25	40
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; ISS:UniProtKB.::GO:0009099; P:valine biosynthetic process; ISS:UniProtKB.
49	Q57725	591	ILVB_METJA Probable acetolactate synthase lar...	521	6e-20	97.1	26	41
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
50	Q9UJ83	578	HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 OS=Homo...	496	9e-20	96.7	23	45	GO:0005782; C:peroxisomal matrix; TAS:Reactome.
									GO:0016830; F:carbon-carbon lyase activity; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IDA:UniProtKB.
									GO:0001561; P:fatty acid alpha-oxidation; IDA:HGNC.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.
51	P07342	687	ILVB_YEAST Acetolactate synthase catalytic su...	512	2e-18	92.8	25	41	GO:0005948; C:acetolactate synthase complex; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0003984; F:acetolactate synthase activity; IDA:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IDA:SGD.
52	P27868	579	ILVB_SPIPL Acetolactate synthase OS=Spirulina...	503	4e-18	91.7	23	41
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
53	O78518	575	ILVB_GUITH Acetolactate synthase large subuni...	498	4e-18	91.3	24	40	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
54	Q6SSJ3	718	ILVB_CRYNV Acetolactate synthase, mitochondri...	517	6e-18	91.3	23	40	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
55	O33112	625	ILVB_MYCLE Acetolactate synthase OS=Mycobacte...	506	6e-18	90.9	23	41
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
56	Q5KPJ5	718	ILVB_CRYNJ Acetolactate synthase, mitochondri...	520	1e-17	90.5	23	40	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
57	P0A623	618	ILVB_MYCBO Acetolactate synthase OS=Mycobacte...	501	1e-17	90.1	22	41
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
58	P0A622	618	ILVB1_MYCTU Acetolactate synthase large subun...	501	1e-17	90.1	22	41
									GO:0003984; F:acetolactate synthase activity; IDA:MTBBASE.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE.::GO:0030975; F:thiamine binding; IDA:MTBBASE.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0040007; P:growth; IMP:MTBBASE.::GO:0009097; P:isoleucine biosynthetic process; IMP:UniProtKB.::GO:0009099; P:valine biosynthetic process; IMP:UniProtKB.
59	P40811	574	ILVI_SALTY Acetolactate synthase isozyme 3 la...	502	1e-17	89.7	23	42
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
60	Q02137	575	ILVB_LACLA Acetolactate synthase large subuni...	492	2e-17	89.4	25	43
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
61	P42463	626	ILVB_CORGL Acetolactate synthase large subuni...	492	2e-17	89.4	25	39
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.

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