Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR133W
Length:
582
Number of sequences:
5887
Description:
YLR133W CKI1 SGDID:S000004123, Chr XII from 408445-410193, Genome Release 64-1-1, Verified ORF, "Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P20485    582   KICH_YEAST Choline kinase OS=Saccharomyces ce...5820     1204     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IDA:SGD.::GO:0004305; F:ethanolamine kinase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:SGD.
2Q03764    534   EKI1_YEAST Ethanolamine kinase OS=Saccharomyc...5892e-111     350     34     55GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IDA:SGD.::GO:0004305; F:ethanolamine kinase activity; IMP:SGD.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:SGD.
3Q10276    456   KICH_SCHPO Putative choline kinase OS=Schizos...4981e-49     183     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; ISS:PomBase.
4Q9Y259    395   CHKB_HUMAN Choline/ethanolamine kinase OS=Hom...3645e-28     119     26     45GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IDA:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
5O55229    394   CHKB_MOUSE Choline/ethanolamine kinase OS=Mus...3573e-25     111     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; ISS:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0007517; P:muscle organ development; IMP:MGI.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; ISS:UniProtKB.
6O54783    394   CHKB_RAT Choline/ethanolamine kinase OS=Rattu...3603e-23     105     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; ISS:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; ISS:UniProtKB.
7P35790    457   CHKA_HUMAN Choline kinase alpha OS=Homo sapie...3845e-20     96.7     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IDA:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0006869; P:lipid transport; TAS:ProtInc.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
8O54804    453   CHKA_MOUSE Choline kinase alpha OS=Mus muscul...3762e-19     95.1     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; ISS:UniProtKB.::GO:0004104; F:cholinesterase activity; IDA:MGI.::GO:0008144; F:drug binding; ISS:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; ISS:UniProtKB.
9Q01134    453   CHKA_RAT Choline kinase alpha OS=Rattus norve...3764e-19     94     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0033265; F:choline binding; IDA:RGD.::GO:0004103; F:choline kinase activity; ISS:UniProtKB.::GO:0008144; F:drug binding; ISS:UniProtKB.::GO:0004305; F:ethanolamine kinase activity; ISS:UniProtKB.
GO:0019695; P:choline metabolic process; IDA:RGD.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; ISS:UniProtKB.
10Q869T9    349   EKIA_DICDI Probable ethanolamine kinase A OS=...3591e-18     90.9     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
11Q9NVF9    386   EKI2_HUMAN Ethanolamine kinase 2 OS=Homo sapi...3211e-17     88.6     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
12A7MCT6    385   EKI2_MOUSE Ethanolamine kinase 2 OS=Mus muscu...3255e-17     86.7     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:MGI.::GO:0001890; P:placenta development; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.
13D3ZRW8    385   EKI2_RAT Ethanolamine kinase 2 OS=Rattus norv...3219e-16     82.8     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
14P54352    518   EAS_DROME Ethanolamine kinase OS=Drosophila m...3250.000000000000002     82.8     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; NAS:FlyBase.::GO:0004305; F:ethanolamine kinase activity; IDA:FlyBase.
GO:0008306; P:associative learning; TAS:FlyBase.::GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.::GO:0046959; P:habituation; TAS:FlyBase.::GO:0007616; P:long-term memory; TAS:FlyBase.::GO:0007638; P:mechanosensory behavior; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0046337; P:phosphatidylethanolamine metabolic process; IDA:FlyBase.::GO:0001666; P:response to hypoxia; IDA:FlyBase.
15P46559    369   KICB2_CAEEL Choline kinase B2 OS=Caenorhabdit...3610.0000000000002     75.5     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IDA:WormBase.
16A7SK27    349   EKI_NEMVE Probable ethanolamine kinase OS=Nem...3490.000000000003     72     23     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
17P46558    371   KICB1_CAEEL Choline kinase B1 OS=Caenorhabdit...3750.000000000006     71.2     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IEA:EC.
GO:0019915; P:lipid storage; IMP:WormBase.
18Q9D4V0    412   EKI1_MOUSE Ethanolamine kinase 1 OS=Mus muscu...3200.00000000001     70.5     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
19Q9HBU6    452   EKI1_HUMAN Ethanolamine kinase 1 OS=Homo sapi...3270.00000000002     70.1     23     40GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
20P46560    368   KICB3_CAEEL Putative choline kinase B3 OS=Cae...3560.00000000009     67.4     24     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004103; F:choline kinase activity; IEA:EC.
21Q554D8    447   EKIB_DICDI Probable ethanolamine kinase B OS=...930.0006     46.2     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004305; F:ethanolamine kinase activity; IEA:EC.
GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
22P32607    177   RTG1_YEAST Retrograde regulation protein 1 OS...860.22     37     29     43GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
GO:0071400; P:cellular response to oleic acid; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
23P38796    400   PPME1_YEAST Protein phosphatase methylesteras...1643.7     33.9     21     42GO:0005763; C:mitochondrial small ribosomal subunit; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0004091; F:carboxylesterase activity; IDA:SGD.::GO:0003735; F:structural constituent of ribosome; IDA:SGD.
GO:0032543; P:mitochondrial translation; IC:SGD.::GO:0006464; P:protein modification process; IGI:SGD.
24Q6BPK1    1123   MED14_DEBHA Mediator of RNA polymerase II tra...1367.3     33.5     24     48GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
records
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