Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR131C
Length:
770
Number of sequences:
5887
Description:
YLR131C ACE2 SGDID:S000004121, Chr XII from 406822-404510, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that activates genes required for cytokinesis; phosphorylation by Cbk1p blocks nuclear exit of Ace2p during the M-to-G1 transition, causing its specific localization to daughter cell nuclei; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q1LYE3    623   ZN143_DANRE Zinc finger protein 143 OS=Danio ...970.00003     51.2     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92O08584    283   KLF6_MOUSE Krueppel-like factor 6 OS=Mus musc...860.000000002     62.8     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93O75840    302   KLF7_HUMAN Krueppel-like factor 7 OS=Homo sap...860.000000002     63.2     34     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
94Q5JT82    389   KLF17_HUMAN Krueppel-like factor 17 OS=Homo s...550.08     39.7     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95A6QQW0    613   ZN143_BOVIN Zinc finger protein 143 OS=Bos ta...970.0000004     57     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
96Q9YIB7    497   ZIC2B_XENLA Zinc finger protein ZIC 2-B OS=Xe...880.00000002     61.2     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0042074; P:cell migration involved in gastrulation; ISS:UniProtKB.::GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB.
97Q8VHT8    363   TF3A_RAT Transcription factor IIIA OS=Rattus ...740.032     40.8     32     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98Q9NW07    568   ZN358_HUMAN Zinc finger protein 358 OS=Homo s...790.001     46.2     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035115; P:embryonic forelimb morphogenesis; ISS:UniProtKB.::GO:0021915; P:neural tube development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99O95409    532   ZIC2_HUMAN Zinc finger protein ZIC 2 OS=Homo ...880.00000002     61.2     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007420; P:brain development; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB.
100Q6DJQ6    441   ZIC3_XENTR Zinc finger protein ZIC 3 OS=Xenop...880.00000006     59.7     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007368; P:determination of left/right symmetry; ISS:UniProtKB.::GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014034; P:neural crest cell fate commitment; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
101Q91689    503   ZIC2A_XENLA Zinc finger protein ZIC 2-A OS=Xe...880.00000002     61.2     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:UniProtKB.::GO:0042074; P:cell migration involved in gastrulation; IMP:UniProtKB.::GO:0050768; P:negative regulation of neurogenesis; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; IMP:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB.
102O57311    441   ZIC3_XENLA Zinc finger protein ZIC 3 OS=Xenop...880.00000006     59.7     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.::GO:0000578; P:embryonic axis specification; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014034; P:neural crest cell fate commitment; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103Q62520    530   ZIC2_MOUSE Zinc finger protein ZIC 2 OS=Mus m...880.00000003     60.8     35     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IMP:UniProtKB.
104Q8K1M4    789   GLIS1_MOUSE Zinc finger protein GLIS1 OS=Mus ...760.00002     52     37     51GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105P25490    414   TYY1_HUMAN Transcriptional repressor protein ...630.7     37     32     49GO:0031011; C:Ino80 complex; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0000400; F:four-way junction DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034644; P:cellular response to UV; IMP:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106O62651    449   WT1_PIG Wilms tumor protein homolog OS=Sus sc...670.017     42     36     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
107P19544    449   WT1_HUMAN Wilms tumor protein OS=Homo sapiens...670.016     42     36     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0060923; P:cardiac muscle cell fate commitment; ISS:BHF-UCL.::GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IGI:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IGI:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; IDA:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; IGI:UniProtKB.
108O73689    443   ZIC1_XENLA Zinc finger protein ZIC 1 OS=Xenop...880.00000003     60.5     35     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021904; P:dorsal/ventral neural tube patterning; IMP:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; IMP:UniProtKB.::GO:0001840; P:neural plate development; IMP:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
109P23803    392   ODD_DROME Protein odd-skipped OS=Drosophila m...840.000000004     62.8     43     55GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:FlyBase.::GO:0007443; P:Malpighian tubule morphogenesis; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007366; P:periodic partitioning by pair rule gene; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110P49952    448   WT1_RAT Wilms tumor protein homolog OS=Rattus...670.017     42     36     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
111Q7TQ40    622   ZIC5_MOUSE Zinc finger protein ZIC 5 OS=Mus m...580.013     42.7     29     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.
112Q00899    414   TYY1_MOUSE Transcriptional repressor protein ...630.72     36.6     32     49GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051276; P:chromosome organization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0006403; P:RNA localization; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113P22561    449   WT1_MOUSE Wilms tumor protein homolog OS=Mus ...670.018     42     36     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; IMP:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0060923; P:cardiac muscle cell fate commitment; IMP:BHF-UCL.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060976; P:coronary vasculature development; TAS:DFLAT.::GO:0060539; P:diaphragm development; IMP:UniProtKB.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; IMP:UniProtKB.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0060231; P:mesenchymal to epithelial transition; IMP:UniProtKB.::GO:0001823; P:mesonephros development; IMP:MGI.::GO:0072278; P:metanephric comma-shaped body morphogenesis; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; IMP:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; IMP:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; IMP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IMP:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072166; P:posterior mesonephric tubule development; IMP:UniProtKB.::GO:0003156; P:regulation of organ formation; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IDA:UniProtKB.::GO:0007530; P:sex determination; IMP:MGI.::GO:0007356; P:thorax and anterior abdomen determination; IMP:UniProtKB.::GO:0009888; P:tissue development; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.::GO:0061032; P:visceral serous pericardium development; IMP:UniProtKB.
114B7ZSG3    414   WT1A_XENLA Wilms tumor protein homolog A OS=X...600.0006     46.6     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:1900207; P:negative regulation of pronephric nephron tubule development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0039004; P:specification of pronephric proximal tubule identity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
115Q99612    283   KLF6_HUMAN Krueppel-like factor 6 OS=Homo sap...860.000000005     61.6     33     56GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116Q8NBF1    620   GLIS1_HUMAN Zinc finger protein GLIS1 OS=Homo...760.00002     51.6     37     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
117B5DE03    413   WT1_XENTR Wilms tumor protein homolog OS=Xeno...570.00002     51.6     37     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
118P55878    556   GLI1_CHICK Zinc finger protein GLI1 OS=Gallus...890.000003     54.3     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119P10070    1586   GLI2_HUMAN Zinc finger protein GLI2 OS=Homo s...850.000000006     63.5     33     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0021696; P:cerebellar cortex morphogenesis; ISS:UniProtKB.::GO:0048589; P:developmental growth; ISS:UniProtKB.::GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.::GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.::GO:0021508; P:floor plate formation; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0007442; P:hindgut morphogenesis; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0021983; P:pituitary gland development; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0009954; P:proximal/distal pattern formation; ISS:UniProtKB.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; ISS:UniProtKB.::GO:0021965; P:spinal cord ventral commissure morphogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120Q0VGT2    1544   GLI2_MOUSE Zinc finger protein GLI2 OS=Mus mu...850.000000006     63.5     33     54GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0048754; P:branching morphogenesis of a tube; IMP:MGI.::GO:0008283; P:cell proliferation; IGI:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.::GO:0021508; P:floor plate formation; IMP:MGI.::GO:0060322; P:head development; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0007442; P:hindgut morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001822; P:kidney development; IGI:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0060603; P:mammary gland duct morphogenesis; IMP:MGI.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060032; P:notochord regression; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0002076; P:osteoblast development; IDA:MGI.::GO:0021983; P:pituitary gland development; IGI:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060513; P:prostatic bud formation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI.::GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IMP:MGI.::GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IGI:MGI.::GO:0021965; P:spinal cord ventral commissure morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q9Y5W3    355   KLF2_HUMAN Krueppel-like factor 2 OS=Homo sap...682.3     35     32     44GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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