Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR131C
Length:
770
Number of sequences:
5887
Description:
YLR131C ACE2 SGDID:S000004121, Chr XII from 406822-404510, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that activates genes required for cytokinesis; phosphorylation by Cbk1p blocks nuclear exit of Ace2p during the M-to-G1 transition, causing its specific localization to daughter cell nuclei; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P18738    112   ZG9_XENLA Gastrula zinc finger protein XlCGF9...930.0000003     54.3     37     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62P52747    638   ZN143_HUMAN Zinc finger protein 143 OS=Homo s...970.0000006     56.6     30     52GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
63Q8BLM0    355   KLF8_MOUSE Krueppel-like factor 8 OS=Mus musc...591.3     35.8     25     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64P19538    1397   CI_DROME Transcriptional activator cubitus in...890.000001     56.2     34     51GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0035301; C:Hedgehog signaling complex; IPI:FlyBase.::GO:0016020; C:membrane; IDA:FlyBase.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035017; P:cuticle pattern formation; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0008544; P:epidermis development; IMP:FlyBase.::GO:0048592; P:eye morphogenesis; IMP:FlyBase.::GO:0035224; P:genital disc anterior/posterior pattern formation; IEP:FlyBase.::GO:0060914; P:heart formation; IMP:FlyBase.::GO:0035217; P:labial disc development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:FlyBase.::GO:0045750; P:positive regulation of S phase of mitotic cell cycle; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0007367; P:segment polarity determination; IMP:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0035277; P:spiracle morphogenesis, open tracheal system; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048100; P:wing disc anterior/posterior pattern formation; IMP:FlyBase.
65Q92664    365   TF3A_HUMAN Transcription factor IIIA OS=Homo ...820.98     36.2     29     50GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009303; P:rRNA transcription; TAS:ProtInc.::GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
66Q9H9D4    720   ZN408_HUMAN Zinc finger protein 408 OS=Homo s...560.039     41.2     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67Q08ER8    600   ZN543_HUMAN Zinc finger protein 543 OS=Homo s...1290.0003     47.8     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68Q9Z0Z7    446   KLF5_MOUSE Krueppel-like factor 5 OS=Mus musc...840.0000000006     65.9     35     57GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0030033; P:microvillus assembly; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69Q8TDD2    431   SP7_HUMAN Transcription factor Sp7 OS=Homo sa...580.019     42     29     57GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0017151; F:DEAD/H-box RNA helicase binding; ISS:BHF-UCL.::GO:0003677; F:DNA binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001649; P:osteoblast differentiation; ISS:BHF-UCL.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70Q567C6    316   ZN367_DANRE Zinc finger protein 367 OS=Danio ...650.0000000006     64.7     43     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
71Q58DZ6    567   ZN143_XENTR Zinc finger protein 143 OS=Xenopu...970.000001     55.8     29     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72Q60793    483   KLF4_MOUSE Krueppel-like factor 4 OS=Mus musc...800.0000000008     65.5     34     56
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009913; P:epidermal cell differentiation; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
73Q91853    565   ZN143_XENLA Zinc finger protein 143 OS=Xenopu...970.000001     55.5     29     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74O70230    638   ZN143_MOUSE Zinc finger protein 143 OS=Mus mu...970.000005     53.5     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75Q60843    354   KLF2_MOUSE Krueppel-like factor 2 OS=Mus musc...580.49     37.4     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0043249; P:erythrocyte maturation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q5XIU2    638   ZN143_RAT Zinc finger protein 143 OS=Rattus n...970.000005     53.5     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77Q8VI67    428   SP7_MOUSE Transcription factor Sp7 OS=Mus mus...580.022     41.6     29     57GO:0005634; C:nucleus; IDA:MGI.
GO:0017151; F:DEAD/H-box RNA helicase binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78C7EMF5    387   KLF17_PIG Krueppel-like factor 17 OS=Sus scro...540.29     38.1     33     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79P46099    358   KLF1_MOUSE Krueppel-like factor 1 OS=Mus musc...830.0000000009     64.7     31     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q2QGD7    858   ZXDC_HUMAN Zinc finger protein ZXDC OS=Homo s...701.7     35.8     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0030275; F:LRR domain binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81Q14872    753   MTF1_HUMAN Metal regulatory transcription fac...1150.00007     50.1     29     46GO:0005634; C:nucleus; IDA:HPA.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82Q9ET58    351   KLF2_RAT Krueppel-like factor 2 OS=Rattus nor...580.64     37     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071347; P:cellular response to interleukin-1; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IMP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83Q62521    466   ZIC3_MOUSE Zinc finger protein ZIC 3 OS=Mus m...880.00000002     60.8     35     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035545; P:determination of left/right asymmetry in nervous system; IMP:UniProtKB.::GO:0001947; P:heart looping; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
84O60481    467   ZIC3_HUMAN Zinc finger protein ZIC 3 OS=Homo ...880.00000002     60.8     35     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85Q8VHT7    364   TF3A_MOUSE Transcription factor IIIA OS=Mus m...720.011     42.4     33     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86Q07243    675   MTF1_MOUSE Metal regulatory transcription fac...1150.00009     49.7     29     46GO:0005634; C:nucleus; IC:MGI.
GO:0035035; F:histone acetyltransferase binding; IPI:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0046686; P:response to cadmium ion; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87O43474    513   KLF4_HUMAN Krueppel-like factor 4 OS=Homo sap...581.6     35.8     29     43GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.::GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.::GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
88Q99JB0    301   KLF7_MOUSE Krueppel-like factor 7 OS=Mus musc...860.000000002     63.5     34     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89A6NM28    416   ZFP92_HUMAN Zinc finger protein 92 homolog OS...620.003     44.7     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90O35819    283   KLF6_RAT Krueppel-like factor 6 OS=Rattus nor...860.000000002     62.8     33     56GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; IEP:RGD.
91Q1LYE3    623   ZN143_DANRE Zinc finger protein 143 OS=Danio ...970.00003     51.2     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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