Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR131C
Length:
770
Number of sequences:
5887
Description:
YLR131C ACE2 SGDID:S000004121, Chr XII from 406822-404510, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that activates genes required for cytokinesis; phosphorylation by Cbk1p blocks nuclear exit of Ace2p during the M-to-G1 transition, causing its specific localization to daughter cell nuclei; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P21192    770   ACE2_YEAST Metallothionein expression activat...7700     1581     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:2001043; P:positive regulation of cytokinetic cell separation involved in cell cycle cytokinesis; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.
2P08153    709   SWI5_YEAST Transcriptional factor SWI5 OS=Sac...2940.089     40     27     44GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0036033; F:mediator complex binding; IMP:SGD.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031496; P:positive regulation of mating type switching; IMP:SGD.::GO:0007074; P:positive regulation of transcription on exit from mitosis, from RNA polymerase II promoter; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3O14258    533   ACE2_SCHPO Metallothionein expression activat...1182e-25     115     48     58GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0045896; P:regulation of transcription during mitosis; IGI:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P58334    251   KLF16_MOUSE Krueppel-like factor 16 OS=Mus mu...580.002     44.3     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007212; P:dopamine receptor signaling pathway; IDA:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9BXK1    252   KLF16_HUMAN Krueppel-like factor 16 OS=Homo s...580.034     40.4     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...1270.00000000000004     79     33     56
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q9Y2Y9    288   KLF13_HUMAN Krueppel-like factor 13 OS=Homo s...727.2     33.5     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
8O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...800.0004     47.8     31     49GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
9Q9JJZ6    289   KLF13_MOUSE Krueppel-like factor 13 OS=Mus mu...727.4     33.1     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.::GO:0045647; P:negative regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q90WR8    771   SP3_CHICK Transcription factor Sp3 OS=Gallus ...610.0009     46.6     34     54GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q02447    781   SP3_HUMAN Transcription factor Sp3 OS=Homo sa...610.0008     46.6     34     54GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
12Q8K1S5    502   KLF11_MOUSE Krueppel-like factor 11 OS=Mus mu...640.014     42.4     31     50GO:0005634; C:nucleus; IC:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
13O89091    479   KLF10_MOUSE Krueppel-like factor 10 OS=Mus mu...890.0000000000002     77     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030282; P:bone mineralization; IMP:MGI.::GO:0045672; P:positive regulation of osteoclast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14O14901    512   KLF11_HUMAN Krueppel-like factor 11 OS=Homo s...640.021     42     31     50GO:0005634; C:nucleus; TAS:ProtInc.
GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IDA:BHF-UCL.
15Q9UIH9    416   KLF15_HUMAN Krueppel-like factor 15 OS=Homo s...1270.0000000000002     76.3     32     55GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
16O08876    480   KLF10_RAT Krueppel-like factor 10 OS=Rattus n...890.0000000000003     76.6     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0042127; P:regulation of cell proliferation; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q8TD94    323   KLF14_HUMAN Krueppel-like factor 14 OS=Homo s...580.052     40     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q19A40    323   KLF14_PANTR Krueppel-like factor 14 OS=Pan tr...1100.0000000000004     74.3     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q14V87    323   KLF14_GORGO Krueppel-like factor 14 OS=Gorill...1100.0000000000004     74.3     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q60980    344   KLF3_MOUSE Krueppel-like factor 3 OS=Mus musc...840.0000000000008     73.9     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21P57682    345   KLF3_HUMAN Krueppel-like factor 3 OS=Homo sap...840.000000000001     73.6     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q13118    480   KLF10_HUMAN Krueppel-like factor 10 OS=Homo s...890.000000000001     74.3     37     60GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
23Q09838    681   PRZ1_SCHPO Transcriptional regulator prz1 OS=...790.000000000001     75.1     43     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019722; P:calcium-mediated signaling; IDA:PomBase.::GO:0006874; P:cellular calcium ion homeostasis; IDA:PomBase.
24Q9Y4X4    402   KLF12_HUMAN Krueppel-like factor 12 OS=Homo s...1120.000000000002     73.6     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25P53968    678   CRZ1_YEAST Transcriptional regulator CRZ1 OS=...880.000000000002     73.9     43     53GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019722; P:calcium-mediated signaling; IMP:SGD.::GO:0006038; P:cell wall chitin biosynthetic process; IGI:SGD.::GO:0030007; P:cellular potassium ion homeostasis; IGI:SGD.::GO:2001040; P:positive regulation of cellular response to drug; IMP:SGD.::GO:0061423; P:positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0007329; P:positive regulation of transcription from RNA polymerase II promoter by pheromones; IMP:SGD.::GO:0061422; P:positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; IMP:SGD.::GO:0061400; P:positive regulation of transcription from RNA polymerase II promoter in response to calcium ion; IMP:SGD.::GO:0061404; P:positive regulation of transcription from RNA polymerase II promoter in response to increased salt; IMP:SGD.
26Q01713    244   KLF9_RAT Krueppel-like factor 9 OS=Rattus nor...890.000000000003     70.9     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27P79288    244   KLF9_PIG Krueppel-like factor 9 OS=Sus scrofa...590.007     42.4     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q13886    244   KLF9_HUMAN Krueppel-like factor 9 OS=Homo sap...590.008     42.4     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q01714    786   SP1_RAT Transcription factor Sp1 OS=Rattus no...620.003     44.7     32     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0032993; C:protein-DNA complex; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0035035; F:histone acetyltransferase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
30O89090    784   SP1_MOUSE Transcription factor Sp1 OS=Mus mus...590.003     44.7     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0035326; F:enhancer binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
31Q02446    784   SP4_HUMAN Transcription factor Sp4 OS=Homo sa...620.005     43.9     32     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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